Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: UMLS:C0409974 (
lupus
)
22,386
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The authors report the observation of a young woman 22 years of age having presented the clinical and biological manifestations of disseminated
lupus
erythematosis, followed more than one year later by the appearance of Hodgkin's disease. Several etiopathological hypothesis concerning this association have been discussed but the experimental work of Schwartz has permitted the finding of a common denominator for these two diseases: a RNA virus, type C.
Sem
Hop
PMID:[The association of lupus and Hodgkin's disease. A case history (author's transl)]. 624 72
The study of 36 published cases of adult Still's disease shows the following features: the onset takes place usually during the third decade of life, most often as a polyarthralgia characterized by sometimes starting fever, evanescent rash, neutrophil leukocytosis, negativity of the serological tests for rheumatoid arthritis and systemic
lupus
; lymphadenopathy and splenomegaly are frequent but not constant; serous cavities, particularly pericardium, are rather frequently involved; evolution is characterized by a succession of relapses and remissions, the far prognosis being rather good (1/3 of cures, 1/3 of mild articular relapses, 1/3 of articular sequelae, involving chiefly neck and hips); corticosteroids and heavy doses of aspirin seem to give the best therapeutic results, the usefulness of a maintenance treatment is debatable.
Sem
Hop
PMID:[Adult Still's disease (author's transl)]. 625 65
Acute glomerulopathy due to pneumococcal infection occurred in a patient with chronic discoid
lupus
. The onset of renal involvement in this context suggested that cutaneous
lupus
may have developed into systemic lupus erythematosus. Renal biopsy established the correct diagnosis. The physiopathology of glomerular involvement in
lupus
and infections is discussed. Attention is drawn to the significance of complement activation, either by the classical or the alternative pathways according to the etiology.
Sem
Hop
1982 May 20
PMID:[Proliferative glomerulopathy in pneumococcal septicemia in a patient with lupus (author's transl)]. 628 6
Lupus panniculitis usually affects the hypodermis and the dermis profundus (Irgang's
lupus
profundus). In our case, the systemic lupus erythematosus was preceded by an intraabdominal panniculitis, occurring as a voluminous tumor. Histological examination showed the usual picture of panniculitis, but there were also severe fibrinoid necrotic lesions, which should have alerted us.
Lupus
must be included among the etiologies of intraabdominal panniculitis.
Sem
Hop
1982 Dec 30
PMID:[Pseudo-tumorous panniculitis of the mesentery. An unusual initial stage of acute lupus erythematosus in a 10-year-old girl]. 630 53
Plasma exchange, used since 1979 in the treatment of severe rheumatoid arthritis, has been the subject of numerous publications in the recent years. According to data from a review of the literature and from our personal experience, this therapy cannot be advocated in the usual forms of rheumatoid arthritis. Because of the side-effects, the complicated technical equipment required and the short duration of therapeutic results, plasma exchange should, for the time being, be restricted to malignant forms of rheumatoid arthritis, polyvisceral exacerbations in
lupus
and scleroderma, and hyperviscosity syndromes in globulinopathies.
Sem
Hop
1983 Apr 21
PMID:[Plasma exchange in rheumatology. Technical problems, tolerance, indications]. 630 2
The authors report on a case of hip osteonecrosis caused by
lupus
which necessitated a complete hip prosthesis. 3 years after the intervention, on the occasion of an induced abortion done without preventive antibiotic therapy, a severe infection of the prosthesis was noted, complicated by streptococcal bacteriosis. Being that
lupus
is very sensitive to all forms of infection, it is important to take all possible precautions to avoid secondary infections, which are common among people who wear prostheses, and which usually develop years after initial surgery.
Sem
Hop
Paris 1977 Mar 09
PMID:[Hip prosthesis and post-abortion streptococcal infection in lupus]. 1226 Sep
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