Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0409974 (lupus)
22,386 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fluorescent treponemal antibody absorption tests were performed on serum samples from 43 patients with lupus erythematosus (LE). Seven borderline and three reactive results were obtained from patients who had no evidence of syphilis, and Treponema pallidum immobilization (TPI) tests were nonreactive. These probable nonsyphilitic reactions were associated with discoid LE (DLE) as frequently as with systemic LE (SLE). Three of these serum samples were reactive in the microhemagglutination assay for T pallidum antibodies (MHA-TP), but titers were low. Reactive FTA-ABS tests were also obtained from four patients with LE with evidence of syphilis. All four serum samples were highly reactive in the MHA-TP test. These findings suggest that nonsyphilitic FTA-ABS fluorescence is (1) common with both DLE and SLE, (2) frequently not "beaded" in pattern, and (3) often detectable when MHA-TP tests are performed.
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PMID:Borderline and reactive FTA-ABS. Results in lupus erythematosus. 83 21

Sera of patients with lupus erythematosus can produce false-positive reactions in most serologic tests for syphilis, including the FTA-ABS test. False-positive reactions in the FTA-ABS test can exhibit beaded, borderline or reactive patterns of fluorescence. Beaded fluorescence is commonly associated with anti-DNA antibody and other correlates of lupus activity. Borderline and reactive results are common in both systemic and discoid lupus erythematosus, and are usually not associated with increased clinical activity. TPI and MHA-TP tests appear helpful in detecting false-positive FTA-ABS results.
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PMID:Lupus erythematosus and reactive tests for syphilis: update. 101 53

A 41-year old male who presented for blood donation for the first time was rejected on the grounds of a positive reaginic serological test (VDRL and RPR) and a specific antitrepomena test (FTA) for syphilis. Later studies revealed the existence of a lupus anticoagulant and this was made responsible for the positive serology. Our observation suggests the need to search for the existence of a lupus anticoagulant in blood donors with non-specific or specific positive antitrepenema test.
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PMID:Lupus anticoagulant and false positive serological tests for syphilis. 311 73

We report on a false reactive 19 S (IgM) FTA-Abs test in a case of lupus erythematosus discoides. We are not aware of any similar case described in the literature so far.
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PMID:[Lupus erythematosus simulating syphilis II]. 379 94