Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0409974 (
lupus
)
22,386
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Lichen planus pemphigoides
(
LPP
) is an autoimmune disease characterised by evolution of subepidermal blisters on normal and lichen planus affected skin. We describe a case of
LPP
in a 54-year-old Chinese woman. The patient presented with psoriasiform plaques and was diagnosed with guttate psoriasis. Narrowband ultraviolet B (NBUVB) therapy was commenced, and she experienced a generalised eruption of violaceous papules, bullae over the lower limbs, and Wickham's striae over the buccal mucosa. Histology from a plaque revealed interface dermatitis, while a specimen from a blister showed subepidermal bulla. Direct immunofluorescence showed linear deposition of IgG and C3 along the basement membrane. A diagnosis of
LPP
was made on clinicopathological grounds. This is the first case report of NBUVB alone in unmasking
LPP
. In this case report, we describe the pathological mechanism of NBUVB in the development of
LPP
and key features distinguishing
LPP
from bullous
lupus erythematosus
, bullous lichen planus, bullous pemphigoid, and psoriasis.
...
PMID:Narrowband UVB-induced lichen planus pemphigoide. 2538 95
