Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0406810 (
NAME
)
13,345
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
nitric oxide synthase
5046
CAR
2438
Sep
927
cyclooxygenase
549
inducible nitric oxide synthase
516
ATP
504
Mol
502
eNOS
464
guanylate cyclase
460
angiotensin II
409
superoxide dismutase
393
endothelial nitric oxide synthase
346
neuronal nitric oxide synthase
326
bradykinin
322
cytokine
312
lipopolysaccharide
306
catalase
295
PXR
280
insulin
276
endothelin-1
238
CD19
229
renin
215
soluble guanylyl cyclase
202
Ang II
194
guanylyl cyclase
184
GSH
177
vascular endothelium
160
substance P
159
collagen
155
NMDA receptor
155
nuclear receptor
153
phosphodiesterase
150
hemoglobin
150
LPS
149
DVB
147
TNF
144
constitutive androstane receptor
140
SNAP
133
xenobiotic
133
SIN
129
SOD
129
tumor necrosis factor
125
cytochrome P450
124
5-hydroxytryptamine
121
calcitonin
120
ATPase
119
albumin
118
NR1I3
115
caspase-3
111
COX-2
109
vasopressin
109
constitutive nitric oxide synthase
103
PKG
100
myeloperoxidase
98
A-I
98
muscarinic receptor
93
PI3K
88
DAF
86
vascular endothelial growth factor
86
pregnane X receptor
85
Gen
85
NADPH
85
ANG
83
glutathione peroxidase
83
ROS
82
ET-1
80
lactate dehydrogenase
78
AMP
78
tap
77
AT1
77
COX-1
77
gut
75
heme oxygenase-1
73
CO2
71
MAPK
69
IL-6
68
FXR
66
thrombin
66
calmodulin
65
ERK1
64
CYP3A4
64
polypeptide
64
calcium channel
64
ADP
64
adenylate cyclase
64
COX
63
ETA
62
Ah receptor
61
p38
60
tyrosine kinase
60
IFN
59
NO3
58
PGF
57
xanthine oxidase
56
ETB
55
endoplasmic reticulum
55
TNF-alpha
53
PD-1
53
opioid receptor
52
cyclooxygenase-2
52
MAP
52
GABA
52
CD8
51
adenylyl cyclase
51
CYP2B6
51
oxytocin
50
IFN-gamma
49
ERK
49
CA1
49
fused
48
estrogen receptor
48
PKC
48
Rho
48
NR1I2
47
EFS
47
VEGF
47
mast cell
47
reductase
46
atrial natriuretic peptide
46
adenosine receptor
46
PDE
46
interleukin-6
45
P450
45
phosphatidylinositol 3-kinase
45
Bcl-2
44
CYP
44
rat)
44
HO-1
43
PPAR
43
interferon
42
vasoactive intestinal peptide (VIP)
42
vasoactive intestinal peptide
42
CD28
42
CD4
42
p53
41
leptin
41
arginine vasopressin
41
NK1
41
EDRF
40
PGI
40
tumor necrosis factor alpha
40
glucagon
39
Endothelin-1
39
IL-10
39
CGRP
38
TCR
38
AT2
38
aryl hydrocarbon receptor
38
coxsackievirus and adenovirus receptor
38
interferon-gamma
37
IL-2
37
ACE
37
cage
36
4-1BB
36
ACTH
36
serum albumin
35
ARG
35
antioxidant enzyme
35
Pol
35
CYP3A
35
more...
Disease
NAME
13345
hypertension
1179
cancer
816
tumor
599
ischemia
490
diabetes
296
GSH
177
depression
146
atherosclerosis
127
stroke
115
leukemia
115
cardiovascular disease
102
pulmonary hypertension
102
acute lymphoblastic leukemia
95
sepsis
94
obesity
89
sepsis
89
Evans
87
preeclampsia
85
cerebral ischemia
84
myocardial ischemia
83
ATM
81
myocardial infarction
81
heart failure
80
lymphoma
79
multiple myeloma
75
proteinuria
73
tumor growth
67
cold
65
B-cell lymphoma
61
epilepsy
56
ventricular hypertrophy
56
melanoma
56
hyperglycemia
54
renal disease
54
hematologic malignancies
51
B-ALL
48
PDE
46
hepatocellular carcinoma
46
cholestasis
46
breast cancer
46
fits
44
SEM
44
asthma
42
Hodgkin's disease
42
carcinoma
41
type 2 diabetes
41
uterus
39
erectile dysfunction
39
hypercholesterolemia
39
acute myeloid leukemia
36
solid tumor
35
gastric ulcer
35
glomerulosclerosis
34
HIV
34
infectious diseases
34
chronic lymphocytic leukemia
33
carcinogenesis
33
metastases
33
cirrhosis
32
renal failure
31
pulmonary edema
30
plaque
30
glioma
30
Endothelial dysfunction
30
vascular disease
29
sickle cell disease
29
pertussis
29
Alzheimer's disease
29
chronic lymphocytic leukemia
28
colitis
28
metabolic syndrome
28
Blocking
28
neuroblastoma
27
graft-versus-host disease
26
Adenovirus
25
adenocarcinoma
25
coronary occlusion
25
virus infection
25
Parkinson's disease
24
tumorigenesis
24
ventricular fibrillation
23
minimal residual disease
23
prostate cancer
23
SCH
22
memory impairment
22
acute renal failure
22
multiple endocrine neoplasia
22
schizophrenia
22
coxsackievirus
21
portal hypertension
21
pancreatic cancer
21
tumor progression
21
renal ischemia
21
Infection
21
cognitive impairment
20
Placenta
20
hyperinsulinemia
20
arthritis
20
coronary artery disease
19
immunodeficiency
19
endotoxic shock
19
liver cancer
19
encephalopathy
18
non-Hodgkin's lymphoma
18
dyslipidemia
18
glioblastoma
18
celiac disease
18
Brown
18
malaria
17
colorectal cancer
17
lung cancer
17
diabetic nephropathy
17
genetic hypertension
17
hypoglycemia
17
PCP
16
essential hypertension
16
coronary heart disease
16
retinopathy
16
ovarian cancer
16
hyperhomocysteinemia
16
intraocular pressure
16
liver cancer
15
squamous cell carcinoma
15
CTX
15
Leukemia
15
hyperlipidemia
15
thrombocytopenia
15
migraine
15
fatty liver
15
Frey
14
SDS
14
oral cancer
14
cardiomyopathy
14
anemia
14
gastric lesion
14
pheochromocytoma
14
AIDS
14
glucose intolerance
14
anaphylaxis
14
Thoracic
14
neuropathy
13
malnutrition
13
lymphoblastic leukemia
13
acute pancreatitis
13
hyperphagia
13
urethra
13
catalepsy
13
MRS
13
suicide
13
arteriosclerosis
13
colon cancer
13
NOD
13
aggression
13
chronic renal failure
13
type 1 diabetes
12
West
12
congestive heart failure
12
myocarditis
12
Tumour necrosis
12
more...
Symptom
pain
186
seizures
131
anesthesia
125
hypothermia
45
analgesia
37
exhaustion
36
diarrhea
32
fatigue
32
hypercapnia
32
hyperoxia
29
functional recovery
19
collapse
15
acidity
15
headache
14
acute pain
12
acute stress
12
hepatomegaly
10
weakness
9
agitation
8
respiratory distress
8
orofacial pain
7
starvation
7
cough
6
erythema
6
vomiting
6
polyuria
5
tremor
5
twitching
5
nausea
5
discomfort
5
angina
4
arthralgia
4
incoordination
4
tonic seizure
4
colic
4
ataxia
4
clonus
4
spasm
4
pallor
4
nasal congestion
3
despair
3
dystonia
3
discomfort
3
memory loss
3
thinning
3
flushing
3
overweight
3
hypotonia
3
splenomegaly
3
exertional dyspnea
2
Welt
2
HSA
2
constipation
2
anorexia
2
Anoxia
2
motor symptom
2
sleepiness
2
dyspnea
2
Neuropathic pain
2
myoclonus
2
abnormal gait
2
Scratch
2
back pain
2
stigma
2
myalgia
2
hunger
2
Deafferentation
2
abdominal pain
2
cachexia
2
hypocapnia
2
chorea
1
physical appearance
1
eds
1
Decreased activity
1
Gasping
1
syncope
1
cyanosis
1
Excitability
1
infant diarrhea
1
dizziness
1
abnormal reflex
1
dental pain
1
rhinorrhea
1
Stiffness
1
intestinal bleeding
1
sciatica
1
ketonuria
1
tachypnea
1
Hyposensitivity
1
Spotting
1
dysuria
1
localized edema
1
bradykinesia
1
adipsia
1
distraction
1
rundown
1
insomnia
1
stomach distension
1
dry eye
1
Wind
1
Crushing
1
vertigo
1
abdominal cramps
1
masculinization
1
cancer pain
1
catarrh
1
hyperesthesia
1
asynergy
1
bone pain
1
urinary frequency
1
sneezing
1
renal colic
1
skin damage
1
chills
1
sinus pressure
1
nausea and vomiting
1
paresthesia
1
ENT
1
catatonia
1
Drug
Cardiovasc
268
Indomethacin
188
Nitric Oxide
151
Sodium nitroprusside
101
lysine
83
ROS
82
caffeine
65
nitroglycerin
65
Angiotensin II
63
MAP
59
ascorbate
58
ETA
58
Nephron
54
Methylene blue
48
IFN-gamma
46
Aminoguanidine
45
ICI
45
CaCl2
38
Atropine
38
CaCl2
38
CaCl2
38
IL-2
37
CTX
34
Histamine
28
Captopril
28
BH4
27
Ethanol
25
vitamin E
25
Bosentan
22
Bosentan
22
CSF
20
Phentolamine
19
Ringer's solution
18
PCP
16
NADH
15
CTX
15
CTX
15
7-Nitroindazole
15
Dermatol
15
Simvastatin
14
Ouabain
14
Photofrin
12
Nebivolol
12
EE2
11
Nephron
11
Clonidine
11
Heme
11
Portal
10
ABC
10
Glucagon
10
Vitamin E
9
Pravastatin
8
Fructose
8
Leaf
8
Molsidomine
8
Monit
8
Propofol
7
Forskolin
7
Tocilizumab
7
Dial
7
TTC
7
Salbutamol
7
Iloprost
7
Omeprazole
6
Rutin
6
Theophylline
6
APD
6
CAM
6
Glybenclamide
6
Rosuvastatin
6
Asn
6
Valsartan
5
EPA
5
Lovastatin
5
Pilocarpine
5
ampicillin
5
Asthma
5
Secretin
5
citric acid
5
CIA
5
Guanethidine
5
Lenalidomide
5
Glutathione
5
Castor oil
5
Ginger
5
Kainic acid
4
G-CSF
4
Dihydro
4
Gel
4
MgSO4
4
ROC
4
TAK
4
Rituximab
4
anti-CD33
4
ADM
4
Fluorescein
4
Rolipram
4
Ramipril
4
Nipradilol
4
Rosiglitazone
4
Cilostazol
4
CoCl2
3
CoCl2
3
Sorafenib
3
Raloxifene
3
Albumin
3
Orphan
3
balanced salt solution
3
PPA
3
Ginseng
3
Vitamin B
3
L-tyrosine
3
Silica
3
Mezlocillin
3
SNL
3
Ketorolac
3
Diphenhydramine
3
Ketotifen
3
TAT
3
Papaverine
3
CTC
3
GHRP
3
CTC
3
Gefitinib
3
Magnesium sulfate
3
Phosphoramidon
3
p75
3
IL-1ra
3
EPI
3
EDR
3
Gabapentin
3
VCR
3
Reserpine
3
DHT
3
DHT
3
pyridoxal phosphate
3
Estrogens
3
Bortezomib
2
Bupivacaine
2
ALA
2
PTH
2
Ciprofibrate
2
FLP
2
Ranitidine
2
Bevacizumab
2
Pregabalin
2
Glycerol
2
Emodin
2
Fluorescein
2
Glycyrrhiza
2
ENT
2
Bifidobacterium
2
Doxycycline
2
2-Methoxyestradiol
2
Enalapril maleate
2
DEX
2
-deoxyadenosine
2
Emodin
2
Cilnidipine
2
Lubeluzole
2
more...
Enzyme
NO synthase
2488
NOS
1042
guanylate cyclase
646
superoxide dismutase
473
catalase
315
protein kinase
260
renin
215
mitogen-activated protein kinase
183
phosphodiesterase
150
protein kinase C
148
NADPH oxidase
145
ATPase
122
NADPH-diaphorase
121
NADPH oxidase
115
peroxidase
115
ERK
115
PKG
100
caspase-3
92
ACE
89
lactate dehydrogenase
85
glutathione peroxidase
85
focal adhesion kinase
73
adenylate cyclase
66
CYP3A4
64
xanthine oxidase
64
thrombin
64
heme oxygenase
60
arginase
57
MAP
53
PDE
49
AMP-activated protein kinase
47
alanine aminotransferase
45
phosphatidylinositol 3-kinase
45
phospholipase A2
41
luciferase
40
creatine kinase
39
MEK
39
NQO1
38
AMPK
38
diaphorase
37
chymotrypsin
37
diaphorase
34
alkaline phosphatase
31
phospholipase C
31
lipoxygenase
30
nitrate reductase
29
AMPK
29
nitrate reductase
28
nitrate reductase
28
nitrate reductase
28
tyrosine hydroxylase
28
nitrate reductase
28
nitrate reductase
28
acetylcholinesterase
27
aspartate aminotransferase
24
reverse transcriptase
23
proteasome
22
caspase-9
21
kallikrein
20
PARP
20
calcineurin
18
phosphoinositide 3-kinase
17
glutathione reductase
17
ornithine decarboxylase
17
trypsin
17
cytochrome oxidase
16
glutathione S-transferase
16
UDP-glucuronosyltransferase
16
PCP
16
CD10
16
collagenase
14
monoamine oxidase
14
CaMKII
14
CPT
14
succinate dehydrogenase
13
CPT
13
CPT
13
SPT
13
cGMP phosphodiesterase
12
complex I
12
beta-galactosidase
12
SPT
12
xanthine dehydrogenase
11
adenosine deaminase
11
P-glycoprotein
11
adenosine deaminase
11
RNA polymerase
10
myosin light chain kinase
10
tissue plasminogen activator
10
AST
10
soluble epoxide hydrolase
10
RNase
9
caspase-8
9
aldehyde dehydrogenase
9
gamma-glutamyl transpeptidase
9
glyceraldehyde-3-phosphate dehydrogenase
9
CYP7A1
9
RNase
9
protein phosphatase 2A
9
ACS
8
transcriptase
8
DCF
8
GSK
8
PRA
7
lipase
7
apyrase
7
prostaglandin synthetase
7
citrate synthase
7
tissue kallikrein
7
pepsin
7
thromboxane synthase
7
thromboplastin
7
granzyme B
6
dimethylarginine dimethylaminohydrolase
6
choline acetyltransferase
6
acid phosphatase
6
glyceraldehyde-3-phosphate dehydrogenase
6
IKK
6
aldehyde dehydrogenase
6
MPP
6
aldehyde dehydrogenase
6
aldehyde dehydrogenase
6
aldehyde dehydrogenase
6
aldose reductase
6
ribonuclease
6
5'-nucleotidase
6
GTP cyclohydrolase I
6
firefly luciferase
6
ribonuclease
6
ascorbate peroxidase
5
lipoprotein lipase
5
glyceraldehyde-3-phosphate dehydrogenase
5
carbonic anhydrase
5
urease
5
HSD
5
thymidine kinase
5
PAH
5
urease
5
endothelin-converting enzyme
5
glyceraldehyde-3-phosphate dehydrogenase
5
glyceraldehyde-3-phosphate dehydrogenase
5
tyrosinase
5
cystathionine gamma-lyase
5
prostacyclin synthase
5
1-hydroxylase
5
SNO
5
glucose-6-phosphate dehydrogenase
5
cholinesterase
5
APC
4
PRE
4
pyruvate dehydrogenase
4
15-lipoxygenase
4
argininosuccinate synthetase
4
arginine decarboxylase
4
TSA
4
transglutaminase
4
alcohol dehydrogenase
4
CPR
4
diamine oxidase
4
elastase
4
more...
Compound
arginine
7245
nitric oxide
7188
sodium
1467
Dec
975
cGMP
970
water
866
calcium
853
oxygen
722
ATP
507
Clin
504
potassium
392
nitrate
389
glucose
345
noradrenaline
328
ACh
311
hydrogen
306
DNA
280
salt
264
ethanol
225
prostacyclin
209
Nitro-L-arginine
205
glutamate
201
THE
182
Indomethacin
180
GSH
179
GSH
179
acetate
177
GMP
163
cAMP
153
nitrogen
148
CO2
145
TNF
144
NMDA
127
5-HT
126
creatinine
124
Ang II
124
TEA
116
TEA
116
Cardiol
110
tyrosine
107
phosphate
106
lysine
96
Angiotensin II
95
H2O2
91
benzene
86
NADPH
86
NADPH
85
AMP
83
HCl
82
cysteine
80
PGE2
77
urea
77
ornithine
73
ornithine
73
ornithine
73
ornithine
73
ornithine
73
Phe
72
ADP
72
NO3
70
acetic acid
69
sulfate
68
Insulin
66
caffeine
66
ADP
65
CIT
65
aldosterone
64
zinc
64
ADP
64
N-acetylcysteine
63
COX
63
iron
63
nicotinamide
60
PGE
59
Nitrite
59
Nitrite
58
ETA
58
8-Br-cGMP
57
Methylene blue
57
Adenosine
56
diacetate
56
Off
53
PEG
53
GABA
53
methionine
53
galactose
53
GABA
53
MAP
52
DETA
52
Bradykinin
51
serine
50
leucine
48
MTT
48
threonine
46
alanine
46
Cereb
46
H2S
45
ICI
45
bromide
45
Losartan
45
Phenylephrine
44
methanol
42
Norepinephrine
42
4-AP
42
Morphine
42
MDA
41
Salt
40
Glibenclamide
38
PEG
38
Atropine
38
CaCl2
38
superoxide radical
37
Hearts
36
ACTH
35
Dexamethasone
35
iodine
34
Adrenal
34
CTX
34
Resveratrol
32
Sildenafil
32
barium
32
STZ
32
Tempol
32
Hearts
32
aminomethyl
31
Melatonin
31
Asp
31
Hoe
31
carbonate
31
prostaglandin F2alpha
31
homocysteine
31
DMSO
31
Isoproterenol
30
Capsaicin
29
MEK
28
phenol
28
CAT
28
Histamine
28
UTP
28
DEA
27
EDTA
27
DEA
27
aspartic acid
27
ammonium
27
CAT
27
EDTA
27
CAT
27
DEA
27
MK801
27
Luminal
26
cadmium
26
Gly
25
AMPA
25
NH2
25
androstane
25
gamma-aminobutyric acid
25
Glutamate
24
hydroxylamine
24
DOCA
24
sodium chloride
24
more...