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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Our 14-year experience with the use of isolated ileal segments for replacement of the bilharzial ureter is analyzed retrospectively. Of 52 patients subjected to this procedure followup data were available for 38, in whom 52 ureters were repaired. The results generally were unsatisfactory: the morbidity and mortality rates were high and the percentage of functional improvement was low. The risk was higher for patients with low creatinine clearance. Therefore, we recommend that this operation be avoided when possible. If the operation is unavoidable, tapering of the ileal segment with antireflux ileovesical anastomosis may improve the outcome. Further clinical study must be done.
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PMID:Ileal replacement of the bilharzial ureter: is it worthwhile? 687 68

There is debate concerning the time course and degree of recovery possible after relief of complete unilateral ureteric obstruction. This study in dogs investigates these features. One ureter was occluded for varying periods, and then reimplanted into the bladder. Recovery was monitored by Tc-Sn-labelled diethylene triamine penta acetic acid (D.T.P.A.) scans and renograms together with creatinine clearance studies. The morphological changes were also studied. There was found to be a progressive loss of functional recovery with increasing periods of obstruction, though this was dramatically improved by contralateral nephrectomy once recovery had stabilized. Increased radial scarring developed in the kidney following increasing periods of obstruction.
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PMID:Renal impairment and its reversibility following variable periods of complete ureteric obstruction. 692 68

Partial flap ureteroneocystostomy was applied for the management of bilharzial strictures of the lower ureter for 30 ureters (24 patients). Follow-up excretory urography (IVP) showed improvement or stabilization in 83.3 per cent of renoureteral units. Creatinine clearance improved or remained stable in 79 per cent of cases. Postoperative reflux occurred in 30 per cent of renoureteral units. We recommend partial flap ureteroneocystostomy for the management of bilharzial strictures if submucosal tunnel ureteroneocystostomy is not applicable.
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PMID:Partial flap ureteroneocystostomy for bilharzial strictures of lower ureter. 712 14

Creatinine and [14C]inulin clearance values were nearly the same during stop-flow and free-flow conditions in the cat. We conclude that glomerular filtration is the sole factor in renal excretion of creatinine in this species. Anatomic (bladder vs kidney) and dynamic (slow vs fast urine flow rate) studies indicated insignificant changes occurred in creatinine content of urine as it traversed the ureter and bladder of cats. We conclude that the cat ureter and bladder under conditions of moderate distension are relatively impermeable to creatinine.
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PMID:Mechanism of urinary excretion of creatinine by the cat. 716 66

In order to investigate the renal handling of 3,5,3'-triiodothyronine (T3), we studied the clearance of T3 (CT3) in dogs and the site of tubular secretion and reabsorption of T3 in dog kidney using the stopflow technique (Malvin et al.). Four female dogs, weighing between 12.2 and 17.8 kg, were used for CT3 measurement. Fourteen anesthetized dogs, weighing between 7.8 and 17.5 kg, were used for the stopflow study. After the catheter was inserted into the left ureter, 15% mannitol solution and isotonic saline containing both 0.2% PSP and 0.5% creatinine or 0.1% inulin, were infused and then 10-30 micrograms/kg of T3 or 100 micrograms/kg of T4 was injected as a bolus. When the urine flow reached a stable state of at least 5 ml/min about one-hr after T3 or T4 injection, the ureteral catheter was clamped shut for 10 min. After the release of the clamp, 20 fractions of urine, 1 ml each, were collected sequentially. The changes in pH and PSP concentrations were used as indices of urine from the distal and proximal tubules, respectively. Urinary T3 was determined by RIA. CT3 was obtained by calculating the ratio of the 24-hr urinary T3 excretion to the serum free T3 concentration. CT3, 51.9 +/- 12.3 ml/min, was greater than the clearance of creatinine (Ccr), 23.8 +/- 4.7 ml/min, suggesting that T3 is secreted at the tubules in dogs. Almost immediately after the release of the clamped ureter, the concentration of urinary T3, corrected with excreted urinary creatinine or inulin, was increased, reaching the maximum value at No. 2 or 3 fraction. This maximum urinary T3 value was followed by decreased concentrations of urinary T3, reaching the minimum around No. 13--15 fraction. The fraction with the highest urinary T3 concentration was close to the one with the lowest pH, and the fraction with the lowest urinary T3 concentration was close to the one with the highest PSP concentration. These data suggest that T3 might be reabsorbed or metabolized at the level of the proximal tubules and secreted into the urine at the level of the distal tubules.
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PMID:[Renal handling of 3,5,3'-triiodothyronine (T3) in the dog studied by stopflow analysis]. 718 75

Unilateral ureterosigmoidostomy (U.S.S.) was performed on 15 rabbits and then the animals were sacrificed after 3, 8 and 15 months. The gross appearance of the kidney and radiological investigations revealed enlargement of the pelvis and of the ureter on the operated side although the anastomosis was patent in all cases. In rabbits sacrificed 8 months after U.S.S. an adenomatous polyp was present at the site of anastomosis. Histological examination of the affected kidney showed pyelonephritis secondary to obstruction and immunopathological studies revealed in some rabbits glomerular and tubular deposition of immunoglobulins and complement. The contralateral kidney was always normal. Biochemical investigations showed only a moderate increase in blood urea nitrogen and plasma creatinine values.
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PMID:Renal lesions after unilateral ureterosigmoidostomy in the rabbit: preliminary results. 725 27

The long term result after the operative treatment of 29 ureteral strictures by various methods in 19 patients treated radically for a malignant tumor of the uterus was evaluated an average of 50 months after the urologic reconstructive surgery. Four patients died of repeat carcinoma and one patient died of a pulmonary embolism before the follow-up examination. In the other patients, a clinical examination, isotopic nephrography, intravenous pyelography, midstream culture and sediment as well as serum creatinine assay demonstrated that transureteroureterostomy resulted in a good, or satisfactory, outcome in patients with a unilateral stricture. A similar outcome was obtained by ileal replacement of the ureter, provided renal function had not been impaired preoperatively. The results obtained with the bladder flap operation, ureterolysis and cutaneous ureterostomy were poor. The significance of early detection and active therapy for strictures is emphasized. Nonradiated tissue should be used for the reconstructive procedure.
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PMID:Treatment of ureteral strictures after therapy for carcinoma of the uterus. 741 56

Use of the ileum as a substitute for the ureter should be taken into consideration when urinary tract continuity cannot be restored by using urinary tract tissue. Another important indication for this procedure is recurrent renal calculi, to permit the free passage of stones. It is essential to reserve this operation for those patients whose renal function is relatively adequate. Chronic renal insufficiency with a serum creatinine level above 2.0--2.2 mg% is a contraindication for the operation. Another prerequisite for the operation is that the patient is able to empty his bladder; otherwise deterioration of renal kidney function may occur. The present article gives a review on the ileal ureter, with emphasis on the indications and operative technique.
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PMID:Ileal ureter: current status. 746 Sep 79

In the development of a reliable model for chronic rejection in rat renal allografts, the effect of modifying the ureteric anastomosis was tested. Rats, tolerized by pretreatment with two donor blood transfusions under Cyclosporin A, received renal allografts with either sewn or stented ureter. Control groups received isografts or underwent uninephrectomy with insertion of ureteric stents. For the first 6 days after transplantation, serum creatinine and urea values were lower in allograft recipients with stented ureters than in the group with sewn ureters. The method of ureteric anastomosis did not affect the long-term incidence of abnormal function. Allograft morphology was extremely variable from minor to extensive tubular atrophy, interstitial fibrosis, glomerular hypertrophy, focal and segmental glomerulosclerosis as well as vascular changes. Glomerulosclerosis was absent in controls and increased with time in the allografts. Two hundred days after transplantation all allograft recipients with sewn ureters exhibited some glomerulosclerosis, in half of these kidneys more than 25% of glomeruli were affected. Only 33% recipients of allografts with stented ureters exhibited some glomerulosclerosis and less than 20% of glomeruli were affected. The stented ureteric anastomosis provides a reliable method, a reduction of the technical failure rate, a reduction of the incidence of hydronephrosis, allows more accurate assessment of early renal function and may be of importance in reducing the occurrence and prevalence of glomerulosclerosis in the long-term allografts.
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PMID:The effect of ureteric stenting on the function and morphology of long-term rat renal allografts. 761 71

A fistula between the ureter and the acetabular space developed in a woman 69 years of age after revision surgery for a total hip arthroplasty. Symptoms were intermittent macrohematuria and swelling of the leg. The diagnosis was confirmed by arthrography and an elevated creatinine level in the aspirated fluid. After nephroureterectomy, symptoms disappeared. We conclude that the differential diagnosis of persisting unusual symptoms after total hip replacement has to include a fistula between the total hip prosthesis and urinary tract, even in the absence of open sinuses.
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PMID:Ureteroarticular fistula after total hip replacement. A case report. 769 46


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