Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors report the case of a 13-year-old migrant girl with urinary tuberculosis, presenting with urinary tract infection, severe frequency and unexplained fever. Intravenous urography demonstrated a non-functioning left kidney and a small fibrotic bladder. Retrograde cystography revealed stage 4 right vesicoureteric reflux. The presence of the Koch bacillus was identified on urine culture. Medical treatment by Rifampicin and Isoniazid was instituted for 18 months. Surgical management, consisting of left nephroureterectomy, subtotal cystectomy with augmentation enterocystoplasty and resection of the pelvic part of the right ureter with ureterointestinal reimplantation, was performed. With a follow-up of 19 years, this patient has normal renal function and no urinary disorders. This case recalls the reality of urinary tuberculosis in children and confirms its insidious nature. The destructive course of urinary tuberculosis may require major urinary tract reconstruction, as in our case.
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PMID:[Urinary tuberculosis in children. Report of a severe form with a followup of 19 years]. 1246 28

A 26 years old Bangladeshi man experienced sudden gross haematuria for 10 days when he was working in Italy in June'07 that was resolved spontaneously. Six months' later he again developed haematuria and was admitted into an Italian hospital for its evaluation and management. In the mean time, he developed low grade fever, cough, back pain, spinal angulations, walking difficulty. His X-ray chest postero-anterior view revealed cavitary lesions in upper zones of both lung fields. Intravenous Urography (IVU) was done which revealed hydronephrosis and hydroureter of left kidney. Magnetic Resonance Imaging (MRI) of dorso-lumber spine revealed collapse of D10-12 and L4-5 vertebral bodies with perivertebral and epidural abscess. Sputum and urine smear for Acid-Fast-Bacilli (AFB) demonstrated the organisms on Z-N stain and AFB culture and sensitivity demonstrated that it was resistant to isoniazide, Rifampicin and streptomycin and diagnosed as primary disseminated multi-drug Resistant tuberculosis (MDR-TB). Second-line drugs were started in Italy on 15th January'08 and were continued thereafter in National Institute of Diseases of the Chest and Hospital (NIDCH). A ureteric stent which was given in Italy to get relief of hydro-ureter was removed in Dhaka. A neurosurgery (costo-transversectomy with decompression of spine) was done in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka and patient get relief of back pain paresthesia. Lastly, his sputum and urine AFB smear and AFB culture became negative. So, primary disseminated MDR-TB with renal, spinal and pulmonary involvement was diagnosed in this Bangladeshi man who had a sputum AFB culture and sensitivity during his initial diagnostic work-up in Italy. It's an alarming case that demonstrated necessity of sputum AFB culture and sensitivity during initial diagnostic work-up.
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PMID:Primary disseminated MDR-TB in a Bangladeshi man: a silent and emerging clinical problem for clinicians. 2208 Nov 96