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Gene/Protein
Disease
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Drug
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Target Concepts:
Gene/Protein
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Query: UMLS:C0403608 (
ureter
)
9,655
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Capuchin monkeys exposed to 500-2000 Schistosoma haematobium cercariae were followed for up to 6 1/2 years after infection. Worm burdens decreased as infections became more chronic and decreasing numbers of eggs and active circumoval lesions were found in the bladder and elsewhere.
Nodular
and hyperplastic epithelial lesions of the urinary bladder were not seen during the first year of infection but occurred in 30% of monkeys examined 1-2 years after infection and in 23% of those examined between the second and third years; they were present in only 3% of monkeys studied 3-6 1/2 years after infection. These epithelial proliferative lesions were located near foci of egg deposition and occurred in the monkeys with the most intense active lesions in the bladder. The lesions regressed in animals followed sequentially. The lesions thus appear not to be neoplastic. Obstructive lesions of the
ureter
accompanied by hydronephrosis were present in a few animals. The obstructive uropathy did not appear to cause significant morbidity. Mortality was substantial among infected monkeys at most intervals after infection but was rare among uninfected controls.
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PMID:Pathology of Schistosoma haematobium infection in the capuchin monkey (Cebus apella). 314 Apr 39
The incidence of prostate disease is high. However, accurate assessment of pathological conditions is still difficult. Although CT, MRI, and TRUS imaging methods provide useful information, each has specific drawbacks. Our work examines the potential and utility of 3D trans-urethral ultrasound (TUUS) for improved imaging of the prostate. Four normal canines were examined with TUUS. The catheter was placed in the urethra and used to image the prostate, rectum, bladder,
ureter
, neuro-vascular bundles, arteries, and surrounding tissue. 2D and 3D datasets were acquired and digitized. The 2D data provides useful visualization of the tissue. The clinician was also able to watch urine enter the bladder and perform a digital rectal exam in real-time. 3D data visualization required torodial reconstruction. The algorithm was optimized to provide very fast 3D reconstructions of the prostate. Segmentation of the data proved challenging, but 3D visualization, including volume rendered data and surface rendered data, were well accepted by clinicians. Clinicians and researchers determined a number of potential applications of these new techniques, including: prostate cancer diagnosis and staging, assessment of Benign
Nodular
Enlargement, assessment of physiologic function of the bladder, evaluation of morphologic properties of the prostate, and image guided biopsy and therapy.
...
PMID:Trans-urethral ultrasound (TUUS) imaging for visualization and analysis of the prostate and associated tissues. 1097 25