Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cyclic AMP and cyclic GMP phosphodiesterase (PDE) activities and calmodulin levels were determined in ureters from guinea pigs of the following ages: 50 and 56 days fetuses, three, 10, 21, 50, and 90 days, and three years old. While there is little change in ureteral cyclic AMP-PDE with age, cyclic GMP-PDE increases with age. Activity of cyclic GMP-PDE in supernatants prepared from three-year-old guinea pig ureter homogenates is 462% and 216% higher than that from 50-day fetus and three-day animals, respectively. Calmodulin levels have a bimodal distribution with age; values are highest in supernatants from 10 and 21 day ureters, but also increase in the three-year ureters when compared to 50 and 90-day values.
 ...
PMID:Ontogeny of cyclic AMP and cyclic GMP phosphodiesterase activities and of calmodulin levels in guinea pig ureter. 283 69