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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of Na(+),K(+),2Cl(-) cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 microM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 microM histamine, 10 microM mesatone, 5 mM tetraethylammonium, and 100 microM sodium nitroprusside. Our findings suggest that test substances modulate Na(+),K(+),2Cl(-) cotransport in smooth muscle cells.
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PMID:Effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on electrical and contractile activity of smooth muscle cells in guinea pig ureter. 1463 95