Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0403608 (
ureter
)
9,655
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Twenty-two female children with complete ureteric duplication and ectopic
ureter
(two bilateral) were seen in a 15-year period. The most common clinical presentation was dribbling urinary incontinence with "normal" micturition. Other presentations included urinary infection and vaginal discharge. Four cases were diagnosed after antenatal recognition of ureterohydronephrosis. The clinical diagnosis was supported by various radiological investigations but ultrasonography (US) proved to be particularly reliable in diagnosing ectopic
ureter
. The most common sites of opening of the ectopic
ureter
were the urethral margin or the urethrovaginal septum, although in seven cases the site was not identified. Twenty-one kidneys were managed by upper pole heminephrectomy and three by ureteropyelostomy, removing as much of the ectopic
ureter
as possible via the renal approach. The distal ectopic
ureter
was removed via a separate suprapubic incision at the initial operation in four cases, and in two cases, delayed excision of the distal ectopic
ureter
was necessary. All surgical specimens were examined histologically and only two heminephrectomy specimens showed features of renal dysplasia.
Dribbling
urinary incontinence was cured in all cases, although in one patient the entire kidney was lost after heminephrectomy. Ectopic
ureter
should be suspected in girls with dribbling urinary incontinence. The diagnosis is best supported by US together with conventional radiology. The majority of cases can be managed by heminephrectomy, but when adequate function is demonstrated in the upper pole, ureteropyelostomy is recommended.
...
PMID:Ectopic ureter with complete ureteric duplication in the female child. 147 9