Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0403608 (ureter)
9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

During the 5 years from January, 1985 to December, 1989, 88 patients with transitional cell carcinoma of the renal pelvis and/or ureter were operated curatively in the Department of Urology, Nara Medical University and the affiliated hospitals. There were 66 males and 22 females (3:1) and the mean age was 66.0 years old ranging from 34 to 82. Staging of the renal pelvic and ureteral cancer of each patient was determined by General Rule for Clinical and Pathological Studies on Renal Pelvic and Ureteral Cancer established jointly by Japanese Urological Association and The Japanese Society of Pathology in 1990. The over-all survival rates at 1 and 3 years were 91.2% and 74.0%, respectively. The 3 year survival rates of TS and TE were 80.5% and 41.7%. As for grading, the 3-year survival rates were 75.0% for G1, 70.1% for G2, and 75.2% for G3, respectively. The stage of the tumors affected the prognosis. Of 88 patients 26 (Group 1) received cisplatin based combination chemotherapy as a postoperative adjuvant therapy, and the remaining 62 (Group 2) received no such cytotoxic adjuvant chemotherapy. The 3-year survival rates were 63.3% in Group 1 and 78.9% in Group 2, however mean age of Group 1 was significantly younger than that of Group 2. In spite of the age matched trial, there were no significant differences in survival rates between both groups. Adverse effects of cisplatin based combination chemotherapy included gastrointestinal symptom, fatigue, alopecia and leukopenia, however no serious toxicity was seen. These results suggest that prospective randomized trial would be clarified the efficacy of postoperative adjuvant chemotherapy for patients with renal pelvic and/or ureteral cancer.
...
PMID:[Investigation of postoperative adjuvant chemotherapy in patients with transitional cell carcinoma of the upper urothelium. Nara Urooncology Research Group (NUORG)]. 192 Oct 19

We report a case of metastatic ureteral tumor resulting from gastric cancer in a 56-year-old female. She had undergone distal gastrectomy for gastric cancer in our hospital 3 years earlier, on the histological diagnosis of poorly differentiated adenocarcinoma with absolute curative resection. In March, 1987, she visited our hospital complaining of microscopic hematuria and lumbago. Intravenous pyelography and left retrograde pyelography revealed the stenotic change of the left ureter and hydronephrosis. Endoscopic ureteral biopsy was performed, and the histological diagnosis was an inflammatory change of the ureter. But the hydronephrosis increased, so partial ureterectomy was performed. The histological examination confirmed adenocarcinoma in the left ureter resulting from gastric cancer. From the 340th postoperative day, she complained of general fatigue and vomiting, and gastroscopy revealed recurrent gastric cancer.
...
PMID:[A case of metastatic ureteral tumor]. 219 72

Surgical techniques can be refined and dexterity improved by using angulated needle holders and instruments. This allows the surgeon to place his or her hand in the position of function while suturing either retrograde or antegrade, thus permitting flexion, extension, abduction, adduction, pronation and supination with circumduction to occur without restriction. Under normal circumstances abduction, pronation and extension are limited by anatomic factors, such as the greater mulitangular abutting the longer styloid process of the radius and the stronger ulnar collateral ligament restricting abduction. The chief indication for using angulated needle holders is in retrograde suturing, such as placing posterior row sutures in anastomosing blood vessels, intestine and the ureter. These instruments are not substitutes for straight needle holders but are chiefly an adjunct that permit the surgeon to perform movements with his hand at the wrist joint that are not allowed with the use of straight needle holders which require greater torque in performing operative procedures. They allow better exposure by improving visibility to the area being sutured since the surgeon is not looking down the barrel of the needle holder and has a clear unobstructed view. The instruments permit clamping and suturing of tissues and vessels in small deep wounds that do not readily admit nonangulated hemostats and needle holders, such as those in urologic and gynecologic operations. Instrument tying is easily accomplished because of the short shaft of the instrument, especially in plastic or surface surgical procedures. Furthermore, with angulation, one is able to grasp the needle holder between the thumb and volar aspect of the second and third digits, thus allowing easy retrograde movements that one experiences in grasping a thumb forceps. From the standpoint of medical egonometrics, hand fatigue is reduced since the needle holder does not have to be locked by closing the rings and engaging the serations each time the needle is handed to the surgeon for placement of sutures.
...
PMID:Refinement of a surgical technique using angulated needle holders and surgical instruments. 351 34

Between June, 1987 and December, 1993, ten patients with solitary kidney after total nephroureterectomy for advanced upper urothelial transitional cell carcinoma were treated with chemotherapy (M-VAC or modified M-VAC). This series comprised 6 males and 4 females between 27 and 81 years of age (mean age: 58.5 years). The site of primary lesions was the renal pelvis in one case, ureter in 5 and renal pelvis and ureter in 4. Histologically, these extripated tumors were all identified as transitional cell carcinoma, the stage being pT3 and pT4 in 9 and grade being G3 in 8 of the 10 patients. Among the 13 cases including the 3 cases of recurrence after first line chemotherapy, 7 had lesions suitable for the evaluation. Two of the 7 cases achieved complete response and four achieved partial response, resulting in an 86% response rate. Of the 10 patients, 4 died of metastasis of carcinoma and the others are still alive. The average period after operation among 10 patients was 25 months. Side effects related to this chemotherapy were as follows: general fatigue, nausea or vomiting and alopecia 100%, leucocytepenia (< or = 1,000/mm3) 23%, anemia (RBC < or = 250 x 10(4)/mm3) 62%, thrombocytopenia (< or = 5 x 10(4)/mm3) 46%. However, nephrotoxicity in spite of solitary kidney was not noticed in any patients. From our experience, we suggest that M-VAC or modified M-VAC chemotherapy are safe against patients with a solitary kidney after nephroureterectomy for advanced transitional cell carcinoma of the upper urinary tract.
...
PMID:[Clinical studies of chemotherapy for patients with a solitary kidney after nephroureterectomy for advanced upper urothelial transitional cell carcinoma]. 774 Oct 70

A case of idiopathic retroperitoneal fibrosis is reported. The patient was a 63-year-old man with the complaint of right flank pain, general fatigue and weight loss. Intravenous pyelography revealed right hydronephrosis and peripelvic extravasation. Abdominal computed tomography showed subcapsular urinoma of the right kidney and mass lesion surrounding the aortic bifurcation. Retrograde pyelography demonstrated a narrow segment at the middle portion of the right ureter through which the ureteral catheter could be easily passed. Magnetic resonance imaging showed a low-intensity mass on T1 weighted images and a heterogeneous mass on T2 weighted images. Steroid therapy was selected under the diagnosis of idiopathic retroperitoneal fibrosis with subcapsular urinoma of the right kidney. Prednisolone was administered for 60 days, resulting in the complete disappearance of the urinoma.
...
PMID:[A case of idiopathic retroperitoneal fibrosis with renal subcapsular urinoma resolved by steroid therapy]. 1036 44

An appendiceal abscess was complicated with right hydronephrosis in a 76-year-old woman who complained of general fatigue and fever. Ultrasonography demonstrated right hydronephrosis, and retrograde pyelography confirmed the hydronephrosis and showed ureteral stenosis. Computed tomography scan revealed a low-density area measuring 38 x 35 mm in size, anterior to the right ureter. Ureteroscopy and the biopsy of the mucosa was carried out, but malignant cells were not found. An exploratory laparotomy was performed. The mass had developed from the cecum and involved the ureter, requiring ileocecal excision, left partial ureterectomy and ureteric substitution with a Boari's flap. The histological diagnosis was an appendiceal abscess. The postoperative course was uneventful.
...
PMID:[A case of hydronephrosis associated with appendiceal abscess]. 1199 8

A 72-year-old man was admitted to another hospital because of general fatigue and dyspnea secondary to renal insufficiency. Abdominal computed tomography (CT) and magnetic resonance imaging showed left atrophic kidney, right hydronephrosis, and an intra-pelvic mass of soft-tissue density located anterior to the sacrum, involving the right ureter at the level between the 5th lumber vertebra and the sacrum. He was referred to our hospital after percutaneous nephrostomy was constructed into right kidney. CT-guided needle biopsy revealed the idiopathic retroperitoneal fibrosis, leading us to give him steroid therapy. Three weeks later, radiographic findings showed a remarkable reduction of the mass and the improvement of the right ureteral stricture.
...
PMID:[Idiopathic retroperitoneal fibrosis diagnosed by CT-guided needle biopsy: a case report]. 1869 96

We report a rare case of lung cancer with cavitation that was caused by metastasis of urothelial carcinoma. A 73-year-old woman was admitted to our hospital with macrohematuria and general fatigue in September 2003. Computed tomography revealed a left ureter tumor, which was removed by left nephroureterectomy in October 2003. However, a part of the ureter could not be resected because of the adhesion that had occurred after a previous operation. The patient was diagnosed with sigmoid colon cancer, and she underwent sigmoidectomy and resection of the remaining part of the ureter in August 2004. Subsequently, transurethral resection was performed several times for bladder tumor. The pathological diagnosis in February 2005 was pT2. Cisplatin-based intra-arterial chemotherapy was performed because it was not possible to perform a cystectomy due to the poor performance status. In March 2006, computed tomography of the chest revealed a mass shadow with a cavity in the left lower lung field. This was diagnosed as primary or metastatic lung cancer and was treated by left lower lobectomy in November 2006. On the basis of the pathological findings, we diagnosed the mass as metastatic tumor secondary to the urothelial carcinoma. Despite general chemotherapy, the patient's condition deteriorated, and the patient died 1 year later.
...
PMID:[A case of metastatic lung cancer with cavitation due to urothelial carcinoma]. 2051 25

In healthy population, uric acid comprises the major component of 10-20% of renal stones. Extreme hiperuricaemia is seen in cancer patients with tumour lysis syndrome (TLS) which is classically associated with haematological malignancies with rapid tumour growth rates such as acute lymphoid leukaemia and high grade lymphomas. Primary melofibrosis (Agnogenic myeloid metaplasia-AMM) is a chronic myeloproliferative disease characterized by splenomegaly, a leukoerythroblastic blood picture, teardrop poikilocytosis and varying degrees of marrow fibrosis. Due to the increased extramedullary haematopoiesis, hiperuricemia may occur. However, TLS in patients with AMM is, according to the available literature, described just in one patient. In this paper we present a case of a 47-year-old male patient who was admitted to the hospital with symptoms of fatigue and small amount of urine, and clinical signs of plethora and enlarged spleen. The laboratory findings showed leuko-and erythrocytosis, increased levels of urea-BUN (32 mmol/l) and creatinine (766 mmol/l) as well as uric acid (920 mmol/l). The immediate abdominal ultrasound confirmed extreme splenomegaly, but also showed bilateral hydronephrosis of grade II-III with two stones in proximal part of right ureter and one in proximal part of left ureter as well as empty bladder. Stones were not seen on plain film. Since the patient was in complete anuria, with further rapid elevation of BUN and creatinine levels, bilateral ureteral stents were applicated together with extensive hydration, urine alkalization and administration of allopurinol which resulted in the complete recovery of kidney function. The bone marrow biopsy was also performed and histopathological diagnosis was: Hypercellulary phase of AMM.
...
PMID:Bilateral ureteral obstruction due to primary myelofibrosis caused hyperuricaemia. 2094 7

Reported is the case of a patient who had an appendiceal abscess revealed by right renal colic with fever and general fatigue. The abdominal computed tomography scan showed hydronephrosis and an appendiceal abscess surrounding and compressing the ureter. The appendix contained a stercolith and was perforated.
...
PMID:Appendiceal abscess revealed by right renal colic and hydronephrosis. 2182 29


1 2 Next >>