Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Neurofibromatosis of the urinary tract is estimated to account for 20 per cent of the visceral manifestations of the generalized disease. Among its urological forms involvement of the bladder is the most common. Clinically, neurofibromatosis resembles a tumour, therefore, its early histologic diagnosis is of utmost importance. In the present case a tumour involving the posterior bladder wall was found in a 6 years old boy subjected to examination because of a terminal haematuria. First the tumour was resected, later cystectomy with implantation of the distended ureter into the sigmoid was undertaken because of progression of the tumour. Postoperative hypokalaemia responded to the usual medication. Ureteral distension was reversed by the operation. Though neurofibromatosis (NF) is histologically a benign process, it tends to recur, is invasive, and impairs urinary functions. Therefore, it may endanger life and thus requires cystectomy with surgery for urinary diversion.
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PMID:Neurofibromatosis of the bladder. 392 10

Early and reliable diagnosis is obtained by cultural methods.Pyelographic evidence of renal destruction is necessary as a rule to supplement the positive laboratory findings before resorting to nephrectomy.Bilateral renal tuberculosis should not be diagnosed on the findings of cystoscopy alone.Nephro-ureterectomy is the ideal operation. It prevents the prolongation of the bladder symptoms and the breaking-down of the operation wound and the risk of another operation for the removal of the ureter, not forgetting the danger of infection of the other kidney.Bad results are probably due, in the case of poor patients, to economic and sociological factors which interfere with restoration to health after operation.Genito-urinary tuberculosis is to be regarded not as a localized disorder but as a manifestation of a generalized disease, a fact which necessitates a guarded prognosis and prolonged after-treatment.
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PMID:Observations on Genito-urinary Tuberculosis: (Section of Urology). 1999 Dec 79