Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Upper urinary tract cancer originates in the renal pelvis or ureter and is relatively uncom- mon. The predilection age is 65 to 79 years in Japan. Currently, a diagnosis is usually con- firmed using computed tomography urography. Although radical nephroureterectomy with bladder cuff excision is the gold standard treatment for localized disease, nephron-sparing surgery using a transureteroscopic approach has also been performed for unifocal, small, and low-grade tumors. For advanced disease, platinum-based combination chemotherapy is administered, but there is little known about its effect, unlike for bladder cancer, which is a lower urinary tract cancer. Although older age is reported as one of the prognostic factors in upper urinary tract cancer, age alone should not prevent curative treatment.
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PMID:Pathogenesis and treatment of upper urinary tract cancer. 3054 66