Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report here two new cases of ureteral diverticulosis. This condition is found usually in the man of the fifties who has most frequently an urinary tract infection or a prostatic adenoma. The roentgen findings are multiple out-poutchings of the lumbar ureter. Several factors are combined (constitutionnal, urinary tract infection, disordered ureteral-motility) to explain the creation of diverticules in the areas of weakness of ureteral wall, where penetrate the vessels.
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PMID:[Ureteral diverticulosis (author's transl)]. 41 16

A urodynamic study of patients with prostatic adenoma or other types of cervicoprostatic obstructions demonstrate that ureteral stasis is not a consequence of a direct compression of the intramural ureter by the adenoma but is secondary to dynamic disturbances.
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PMID:Ureteral stasis in cervicoprostatic obstructions. 615 59

Within the framework of perioperative prophylaxis against infections, serum and tissue concentrations were measured following an i. v. bolus injection of 2.0 g of cefotaxime in 25 patients with a prostatic adenoma. The mean serum concentrations were 64.9 microgram/ml, 56.6 microgram/ml, 45.2 microgram/ml, 18.2 microgram/ml and 19.9 microgram/ml 30, 60, 90, 120 and 150 minutes respectively following the injection. The corresponding concentrations in the prostatic adenoma tissue were 8.8 microgram/g, 15.3 microgram/g, 22.9 microgram/g, 4.3 microgram/g and 2.7 microgram/g respectively. The tissue concentrations in ten testes from six patients were measured in a similar way. The maximum concentration (5.4 microgram/g) was also found to occur 90 minutes after the injection. We found very different values, ranging from 0.3 microgram/g to 39.6 microgram/g, in eight kidneys as a result of greatly differing diagnoses and function. Average concentrations of 9.2 microgram/g to 0.8 microgram/g in the ureter, fatty tissue and muscle tissue were within the therapeutically effective range. The cefotaxime concentrations found in serum and tissue lead us to expect successful therapy when cefotaxime is used to treat bacterial infections with sensitive pathogens in the urogenital tract.
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PMID:[Diffusion of cefotaxime in different tissues of the urogenital tract (author's transl)]. 625 Sep 82

Within the framework of perioperative short-term prophylaxis against infections, serum and tissue concentrations were investigated after a single i.v. bolus injection of 2.0 g cefoperazone (Cefobis), a semisynthetic cephalosporin parenterally applicable, in 30 patients with a prostatic adenoma. The mean serum concentrations ranged from 82.0 micrograms/ml at 30 min to 41.9 micrograms/ml at 150 min following the injection decreasing continuously. The corresponding mean concentrations in the tissue of prostatic adenoma were 17.8 micrograms/g and 13.9 micrograms/g, the maximum concentrations were found 90 min after the injection with 21.6 micrograms/g. Most differing concentrations were found in 14 kidneys 90 min after injection. The individual values varied between 5.5 micrograms/g and 70.2 micrograms/g. These ranges of variation must be attributed to the differing clinical and histological diagnoses of the collected organs with highly differing degrees of function. Effective levels of 7.0 micrograms/g to 28.9 micrograms/g were found at different times in 13 testes of 14 patients undergoing plastic orchidectomy because of a carcinoma of the prostata. Average concentrations of 10.3 micrograms/g to 13.2 micrograms/g in the ureter, adipose tissue and muscle were within the therapeutically effective range. The high cefoperazone concentrations found in serum and different tissues lead us to expect successful therapy when cefoperazone is used to treat bacterial infections with sensitive pathogens in the urogenital tract.
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PMID:[Concentration of cefoperazone in various tissues of the urogenital system (author's transl)]. 645 99