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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Previous studies have shown a significant decrease of heparin sulfate proteoglycan (HSPG) in the basement membrane of the glomerulus and the mucosa of the ureter/renal pelvis in patients with calcium nephrolithiasis. In this study, we looked at the localization of another influential proteoglycan, chondroitin sulfate (CSPG), using similar study groups by indirect immunofluorescence staining. Microscopic images were digitized and image analysis was used to quantitate the staining intensity of CSPG present in the basement membrane of the nephron. Our data showed significant loss of CSPG in the Bowman's capsule and the basement membrane of the mucosa of the ureter/renal pelvis using Mann-Whitney U-Wilcoxon Rank Sum W test with P-values of 0.0043 and 0.0041, respectively. However, absence of staining was noted in the basement membrane of the glomerulus and no significant change in the basement membrane of the tubular epithelium was observed. In conclusion, our results showed changes in the localization of CSPG in the basement membrane of the nephron, accompanied with HSPG, which may contribute to the pathological condition of calcium nephrolithiasis.
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PMID:Quantitative analysis on the localization of chondroitin sulfate proteoglycan in renal tissues of patients with calcium nephrolithiasis. 976 1

Therapy for obstructive uropathy is largely determined by whether the obstruction involves one or both kidneys, and by the age of the patient. In the infant and child, obstructive uropathy is almost always due to a congenital malformation of the ureter, bladder, or urethra. Ultrasonographic prenatal diagnosis has permitted early detection and even fetal intervention for posterior urethral valves, although this form of treatment must be considered experimental at present. More important to the affected infant than optimal renal development is the prevention of pulmonary hypoplasia, which is a consequence of fetal oliguria and oligohydramnios. Congenital ureteropelvic junction (UPJ) obstruction is generally unilateral, and although there is controversy regarding the timing of surgical correction, current evidence favors early pyeloplasty. In the adult, obstructive nephropathy is often acquired, with ureteral obstruction usually a consequence of nephrolithiasis. Removal of the stone can be accomplished surgically or by lithotripsy. Bladder outlet obstruction is usually secondary to prostatic hyperplasia, which may progress slowly, allowing a delay in surgical intervention. Neurogenic bladder may require intermittent catheterization or cholinergic therapy; those with hypertonic bladder may benefit from anticholinergics. Regardless of the patient's age, prompt and accurate diagnosis is essential to planning an optimal strategy for the management of obstructive uropathy.
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PMID:Therapeutic approaches in obstructive uropathy. 981 56

Nephrectomy is a radical operation successfully used over more than a century. It should be resorted to only in exceptional situations whenever an organ salvaging operation is precarious for the patient's health (T Patrashkov, 1980). The indications for nephrectomy depend on the type of disease, extent of renal damage, state of the second kidney and the patient's general condition, established by the basic examination methods in urology (T Patrashkov 1982). The study covers 388 nephrectomies in cases presenting diverse diseases of the kidney and ureter, diagnosed and treated in the Department of Urology--University Hospital "Alexandrovska" in the period 1990 to 1995. The commonest causes leading to nephrectomy comprise: 1. Neoplasms of kidney and ureter--134 (34.54%). 1.1. Parenchymal tumors--116 (29.90%)/ 1.2. Papillary tumors--18 (4.64%). 2. Pyonephrosis--88 (22.68%). 3. Nephrolithiasis (presence of renal calculi)--53 (13.66%). 4. Secondary operations of the kidney and ureter--46 (11.86%). 5. Hydronephrosis--38 (9.80%). 6. Anomalies (hypoplasia)--8 (2.06%). 7. Cystic diseases--7 (1.80%). 8. Tuberculosis of kidney--6 (1.55%). 9. Renovasal hypertension--4 (1.02%). 10. Nephrectomy for other diseases--4 (1.02%). As shown by the results the rate of nephrectomy undertaken for renal malignancy is still the highest which is by no means considered as a favourable diagnostic sign.
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PMID:[Kidney diseases most often considered as indications for nephrectomy]. 1148 42

The authors report a case of a male patient with urate nephrolithiasis aggravated with postrenal anuria due to total obturation of the single kidney's ureter with multiple calculi located as a path. The outcome was satisfactory.
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PMID:[A case of total ureteral obturation of a single kidney with urate calculi]. 1243 45

We report a rare case of a retrocaval ureter associated with a left inferior vena cava transposition and with concomitant nephrolithiasis in a young woman already surgically treated during her first years of life for cardiovascular disease. Diagnosis and surgical procedure are described, including the use of a flexible ureterorenoscope to facilitate kidney stone removal.
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PMID:A rare case of retrocaval ureter associated with persistent left vena cava. 1274 May 5

The Siemens Lithostar Litotriptor was used to treat 6 children with cystine nephrolithiasis, previously treated by open surgery. Five children had renal calculi (3 multiple caliceal, 2 pelvis) and one had ureteral calculus. Stone size ranged from 0.2-2.5 cm in diameter, and stone burden was from 0.24 to 10.81 cm3 per kidney. From one to 4 ESWL sessions per unit were applied, with a total of 1,800 to 12,000 shock waves. The stone free rate at 3 months was 50%. A complete elimination was obtained with cystine stones in renal pelvis and ureter, however, up to 4 ESWL treatments failed in caliceal stones. Rather location of cystine calculi than previous surgery was associated with ESWL success rate. Two patients with positive urine cultures were successfully treated with appropriate antibiotics before ESWL was attempted. Perirenal hematoma was major complication demonstrated by radionuclide scintigraphy in one patient, and resolved spontaneously by 3 months. In the combined treatment of cystine urolithiasis in children ESWL, as auxillary procedure, was safe and effective in pelvis stone but failed in caliceal stones. Medical dissolution for retained fragments was found effective.
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PMID:Extracorporeal shock wave lithotripsy for cystine urolithiasis in children: outcome and complications. 1457 84

The accurate diagnosis and quantitation of nephrolithiasis in patients with primary hyperoxaluria (PH) often directly impacts the medical and surgical management for individuals with both symptomatic and asymptomatic calculi. Traditionally, depiction of the size, location and appearance of urinary calculi has been provided by kidney, ureter and bladder plain film radiographs with or without tomography. Given advances in imaging technology there is a shift from conventional radiographs to cross-sectional imaging technology, namely unenhanced computed tomography (CT), CT urography, ultrasound and magnetic resonance imaging. These diagnostic techniques provide differing advantages and disadvantages for imaging stone disease. This review outlines imaging advances in the accurate diagnosis and quantitation of patients with metabolically active stone disease such as PH.
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PMID:Quantitation of stone burden: imaging advances. 1628 80

The aim of the study was to establish the usefulness of ultrasound examination for imaging of stones dislocation in urinary tract after lithotripsy treatment. The study group included 335 children with urolithiasis treated in our Clinic since 1994 until 2005y. In the group were 295 (88%) children with nephrolithiasis and 40 (12%) children with ureterolithiasis. In the whole group 335 children there were performed 619 lithotripsy procedures--545 kidney and 74 ureter units. The ultrasound examinations were performed in each patient before, on the first and second day of the treatment and two months after using the Hitachi EUB 315 with 5Mhz transducer. In the ultrasound examinations after lithotripsy treatment: in 596/619 (96,3%) cases imaging of stones dislocation in urinary tract and urinary retention was possible.
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PMID:[Ultrasound imaging of stones dislocation in urinary tract after lithotripsy treatment in children with urolithiasis]. 1689 10

The incidence of pelvic kidney has been approximated at between 1 in 2200 and 1 in 3000. The ectopic kidney is thought to be no more susceptible to disease than the normally positioned kidney, except for the development of calculi and hydronephrosis. Because of the greater risk of injuring aberrant vessels or overlying abdominal viscera and nerves, the pelvic kidney presents special treatment challenges. Alternative approaches to treating nephrolithiasis may yield better outcomes. The tortuous ureter often associated with a pelvic kidney hinders deflection of the flexible ureteroscope, potentially limiting access. Laparoscopy-guided intervention permits visual exposure of the kidney, enhancing safe puncture and tract placement integral to percutaneous nephrolithotomy. Laparoscopy-assisted anterior retrograde percutaneous nephroscopy involves percutaneous access using a Hunter-Hawkins retrograde nephrostomy needle with adjunctive laparoscopy to permit viewing and manipulation of overlying bowel. Ureteropelvic junction (UPJ) obstruction has been reported to occur in 22% to 37% of ectopic kidneys. Endoscopic incision presents difficulties beyond those of anatomically normal kidneys. The laparoscopic approach provides good surgical exposure, and operative times are comparable to those of laparoscopic pyeloplasty in anatomically normal kidneys. To date, only a handful of cases of malignancy in a pelvic kidney have been described. Like a nonfunctioning anatomically normal kidney, a nonfunctional pelvic kidney may require primary removal. There are a few reports of laparoscopic pelvic nephrectomy. Additional studies are needed to compare the various treatments for disease of the pelvic kidney in order to decide which options have the most beneficial outcomes.
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PMID:Pelvic kidney: associated diseases and treatment. 1817 44

The ureter which runs behind the main lower vein is the evolutionary fault of the vascular system. It is the result of the disorder of the foetal vein canals developments. The clinical symptoms resulting from this fault are: the pains in the lumbar region, hematuria, the recurrent pyelonephritis, nephrolithiasis and the arterial hypertension. Ultrasonography, tomography and magnetic resonans imaging are used in the diagnosis. The best treatment is the operation leading to the restoration of the ureter anatomic position. Nowadays the laparoscopic minimal invasive methods are used more and more often. In this study we described 3 patients. Each of them underwent the operation to correct the ureter position. The result was the improvement of the clinical condition.
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PMID:[Retrocaval ureter]. 1796 89


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