Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty-two patients with extensive pelvic irradiation underwent supravesical urinary diversion using a transverse colon conduit. Primary diseases were most often carcinoma of the cervix and urinary bladder. Indications for diversion included original treatment planning, radiation cystitis, vesicovaginal fistula, and ureteral obstruction. Operative mortality was low (4 per cent), and most complications were managed by further surgery. Normal upper urinary tracts usually remained normal after diversion; relief of existing hydroureteronephrosis was seen in a majority of patients. Stomal problems have been minimal, and renal function has remained normal or stable. The method affords the use of nonirradiated transverse colon as well as the ureter high above the field of pelvic irradiation and is the preferred diversion in such patients.
 ...
PMID:Transverse colon conduit for supravesical urinary tract diversion. 99 48

Between January 1959 and December 1986, 10 of 328 patients (3%) treated with curative intent using primary radiation therapy for carcinoma of the cervix developed obstructive ureteropathy due to fibrosis. The mean age of the patients with obstructive ureteropathy was 45 years and the median time to obstruction was 26 months. The obstruction was unilateral in 8 cases and involved the parametrial portion of the ureter in at least 5 cases. No predisposing risk factor was found to be associated with the development of obstructive ureteropathy. After corrective surgery, renal function remained normal in 8 patients, and resolution of the hydronephrosis occurred in 4 patients.
 ...
PMID:Obstructive ureteropathy following radiation therapy for carcinoma of the cervix. 270 84

The dosage of radiations delivered during gynaecological brachytherapy is usually calculated for the bladder and the rectum. A new technical approach is described in order to known the dose of radiation received by the terminal portion of the ureter. During placement of the Fletcher suit one of the ureters is catheterized by a special stent which appears on the X-rays control used for dosimetry. Data of 16 pre-operative brachytherapies for carcinoma of the cervix were studied. In half of the cases, the dose debit was higher on the ureter than on the bladder and the rectum. In 7 cases, the dose delivered was also higher on the ureter rather than on the bladder and the rectum. And in 3 cases this dose was higher than 50 grays. It is concluded that the ureter is frequently the most irradiated organ in the pelvis during brachytherapy for carcinoma of the cervix. This may be a physiopathologic explanation for some ureterovaginal fistulas occurring after radical hysterectomy.
 ...
PMID:[Ureteral dosimetry during gynecological curietherapy. Possible effects on the occurrence of postoperative ureteral complications]. 362 84

Thirty-five patients with stage Ia epidermoid microinvasive carcinoma of the cervix were treated surgically by vaginal semiradical hysterectomy. The primary features of this new surgical procedure are the removal of an approximately 1-cm portion of vaginal cuff, partial resection of the vesico-uterine ligament for isolation of the ureter, and resection of approximately 2 cm of parametrial tissue. The extent of resection is almost the same as that of the abdominal modified radical hysterectomy. Operation time and blood loss were almost the same as those for simple hysterectomy. No postoperative complications were observed. From these results it is concluded that the method is an adequate, safe, and low-risk operative therapy for patients with microinvasive carcinoma of the cervix.
 ...
PMID:Vaginal semiradical hysterectomy: a new operative procedure for microinvasive carcinoma of the cervix. 650 24

A new method to determine ureteral motility by means of radioisotopes is presented. After administration of 99m-Tc-MDP or 99m-Tc-DTPA urine transport within the ureter is documented by functional way-time-matrices. The special resolution results of a series of 7 to 12 regions of interest covering the ureter out of which the information about its motility is extracted from a series of 300 to 480 single pictures. The time resolution is 1 to 2.5 seconds. The observation period varies between 5 and 20 minutes. Urine transport is outlined as an declined stripe in the matrix. Retroperistaltic waves or dyskinesies can also be detected with this method. 31 patients in whom radical surgery was performed for carcinoma of the cervix were examined by the described functional ureter test. The results show that changes in ureteral function like frequency or quality or even retroperistaltic contractions of the ureter can be observed by the urokinetogram, changes which can be traced neither by isotope renogram nor by intervenous pyelography. Similar observations could be made in 10 patients treated by radiotherapy. In 26 patients the influence of sympathico- and parasympathicomimetic agents on the ureteral motility was studied. The results show that an increase of contraction frequency can be obtained by alpha- and betamimetics and also by cholinesterase inhibitors. These results which are in consistance with the available literature will be analysed and discussed in detail. The urokinetogram opens new possibilities to get insights into the physiology of urine transport and is therefore of great interest as an addition to radiologic and urodynamic methods.
 ...
PMID:[New aspects of registration and drug influence of ureteral motility ]. 675 Sep 29

A woman suffering from carcinoma of the cervix went through radical hysterectomy and radiotherapy. The treatment was complicated by obstruction of the lower left ureter which was dealt with by transureteroureterostomy. Eighteen months later she was admitted with severe stricture of the common pelvic ureter and massive retroperitoneal fibrosis. The afflicted ureteral segment was successfully reformed by intubated ureterotomy.
 ...
PMID:Intubated ureterotomy for ureteral obstruction following radiotherapy and radical hysterectomy. Case report. 849 64

Eleven patients with stage IA2-IIA carcinoma of the cervix have been treated by combined laparoscopic-vaginal radical hysterectomy and bilateral pelvic lymphadenectomy (3-Stage IA2, 5-stage IB, 3-Stage IIA). The patients were unselected. Three patients had bulky (&gte; 5 cms) tumors, one of whom weighed 239 lbs; one had prior anterior-posterior repair, was apareunic and had significant vaginal narrowing; two patients had extensive pelvic adhesions, one of whom also had a 480 gram uterus. Pelvic lymph node metastases were present in one patient and paracervical lymph node metastases in one. The technique used has undergone significant modification. The laparoscopic phase of the procedure contributes much more to the operation than the lymphadenectomy for it allows a symbiotic partitioning of the operation into the laparoscopic and vaginal components. Only those steps of the operation are carried out vaginally that are easier to perform from below (division of the uterosacral and cardinal ligaments, unroofing of the ureter), and they are made much easier by the preceding laparoscopic phase of the operation. Laparoscopic development of the para-vesical and para-rectal spaces makes vaginal entry into these spaces very straightforward, and laparoscopic division of the uterine artery facilitates vaginal unroofing of the ureter. By allowing the proximal ureter to be freed from the medial leaf of the broad ligament, and the proximal attachments and blood supply of the uterus to be divided, the laparoscopic phase of the operation also permits the cervical ligaments to be divided before the ureters are freed from the vesico-cervical ligament, which helps to avoid a Schuchardt incision in most patients.
 ...
PMID:Laparoscopic-Vaginal Radical Hysterectomy 907 93

The Laparoscopic Assisted Surgery Program began in 1991 at The Graduate Hospital. Initially, traditional laparoscopic gynecologic procedures were performed including laparoscopic oophorectomy, hysterectomy, and adhesiolysis. We then began staging patients with ovarian and endometrial cancer laparoscopically. Next, a series of patients who underwent laparoscopic extrafascial hysterectomy with lymph node sampling for endometrial cancer was attempted. In June of 1992, we performed what we believe to be the first completely laparoscopic radical hysterectomy and bilateral pelvic and common iliac lymphadenectomy for a stage IB squamous carcinoma of the cervix. To date fourteen of these procedures have been performed with few complications. The complications encountered thus far include narrowing of a right ureter detected by an intravenous pyelogram obtained on postoperative day 10 and a small vesicovaginal fistula. The narrowed right ureter had a retrograde stent placed as a precaution. It would appear that laparoscopic radical hysterectomy in selected patients offers significant advantages in terms of hospitalization, incision size, and wound, pulmonary, and intestinal complications. In addition to the clinical advantages, laparoscopic radical hysterectomy appears to be more cost effective than traditional laparotomy.
 ...
PMID:Laparoscopic Radical Hysterectomy: A Preliminary Report 907 51

Two patients with invasive carcinoma of the cervix treated with radical hysterectomy developed total unilateral ureteric obstruction postoperatively. A temporary percutaneous nephrostomy was inserted. Because both patients needed adjuvant radiotherapy, intended reimplantation of the ureter was postponed. During this period spontaneous passage through the ureter was observed after 5 and 14 weeks, respectively. It is emphasized that a 'wait and see' policy may be justifiable in the case of ureteric obstruction of unclear etiology after radical hysterectomy for at least 3 months, as long as renal function is preserved by percutaneous nephrostomy drainage of the affected kidney side.
 ...
PMID:Ureteric obstruction after radical hysterectomy. 1157 49

Eighty-three cases of carcinoma of the cervix presenting over a 5-year period, 1997 to 2001 were considered for evaluation of the effects of Irradiation on the urinary tract. Ultrasound scans were used to detect ureteric obstructions in the follow-up period. Significant progressive ureteric obstruction occurred in 6 patients (7.2%), all of whom had malignant strictures. The diagnoses of these strictures were made between 8 months and five years after the Initial treatment. Patients having malignant stricture tend to be in a higher original stage of tumour. The lower ureter was the site of ureteric obstruction in 4 patients while 2 had lesions in middle ureter. The latency period between primary treatment of the tumour and diagnosis of uropathy is significantly shorter for malignant strictures. The site of occurrence of the strictures had no discernible significance but the absence of a bilateral obstruction in spite of all of them being malignant lesions is in disagreement with the published data.
 ...
PMID:Obstructive uropathy following radiation therapy in carcinoma of the uterine cervix. 2111 88


1