Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An antiserum against human epidermal keratins was used to detect keratins in frozen sections of various rabbit and human tissues by indirect immunofluorescence. Strong staining was observed in all stratified squamous epithelia (epidermis, cornea, conjunctiva, tongue, esophagus, vagina, and anus), in epidermal appendages (hair follicle, sebaceous gland, ductal and myoepithelial cells of sweat glands), as well as in Hassall's corpuscles of the thymus, indicating that all contain abundant keratins. No staining by the antiserum was observed in fibroblasts, muscle of any type, cartilage, blood vessel, nerve tissue, iris or lens epithelium, or the glomerular or tubular cells of the kidney. In contrast, the antiserum stained the cells of most epithelia of the intestinal tract, urinary tract (urethra, bladder, ureter, collecting ducts of kidney), female genital tract (cervix, cervical glands, uterus, and oviduct), and respiratory tract (trachea and bronchi). Epithelial cells of the fine ductal system in the pancreas and submaxillary gland also stained well. When primary cultures of epithelial cells derived from bladder, intestine, kidney, and trachea were grown on glass coverslips and stained with anti-keratin, fiber networks similar to those of cultured keratinocytes were observed. These results show that keratins constitute a cytoskeleton in epithelial cells of diverse morphology and embryological origin. The stability of keratin filaments probably confers the structural strength necessary for cells covering a free surface. Keratin staining can be used to obtain information about the origin of cell lines.
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PMID:Keratin cytoskeletons in epithelial cells of internal organs. 11 Dec 42

A study was made of 32 cases of single ectopic ureters (without duplication) to assess the abnormalities observed in the corresponding renal parenchyma and to correlate renal status with location of the ectopic uretic opening. Specimens were obtained from 26 nephrectomies and renal dysplasia was found in 22 cases. There was a close relationship between renal anomalies and location of the ureteric opening. The more remote the ectopic orifice from its normal position, the more severe were the associated renal lesions. Dysplasia was always present when the ectopic ureter opened outside the urinary tract (vagina, Gartner's duct, vestibule, seminal tract). Am embryological concept is proposed to explain the association of renal dysplasia with abnormal location of the ureter opening. It is based on the abnormal--premature or late--appearance of the ureteral bud on the Wolffian duct resulting in the abnormal positioning of the bud on the Wolffian duct with the ureter growing into nephrogenic tissue lacking the potential for normal renal development and leading to renal dysplasia.
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PMID:[Ureter malformations and renal dysplasia--an embryological concept (author's transl)]. 56 40

Excision of the vagina during an operation involving the pelvic ureter or the lower part of the bladder may result in the development of a urinary fistula into the vagina. This risk would seem to be little known, though perfectly explicable on the basis of the close proximity of the structures involved. Certain procedures on the lower urinary tract, including both the pelvic ureter as well as the trigone of the bladder, which may be combined with unfavourable gynaecological circumstances, natural or acquired, may explain such damage to the bladder, with fistula formation. The treatment of these fistulae will be curative, 0ut attention must also be paid to prevention, i.e., cautions and accurate surgical technique adapted to the difficulties encounterd in this region.
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PMID:[The vaginal risk in hypogastric surgery of the pelvic ureter and the trigone of the bladder (author's transl)]. 63 49

The seventh case of a female subject with a single, unilateral ectopic ureter draining to the vagina is reported. The renal unit was located in the renal fossa, wheras in 3 of the 7 cases reported it was within the pelvis. Although ectopia with ureteral duplication is not an uncommon anomaly the single ectopic ureter in the female subject is the rarest form of ureteral ectopia. Use of phenazopyridine hydrochloric acid as an excertory marker was most helpful in locating the vaginal orifice.
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PMID:Single vaginal ectopic ureter: a case report. 70 74

A case of avulsion of a ureter from the pelvioureteral junction and its discharge through the vagina during an attempt to interrupt pregnancy by suction is presented. The preoperative and operative findings are described, as well as the mechanism that caused this kind of trauma. The proposed management of such a case is discussed.
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PMID:Avulsion of the ureter from both ends as a complication of interruption of pregnancy with vacuum aspirator. 87 77

We report on a rare form of bicornuate uterus with simple vagina and isolated hematocervix on right without connection of the right uterus to the vagina. Besides we found an aplasia of the right kidney and ureter. The case specially the isolated hematocervix and therapeutic problems of this double anomaly are discussed.
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PMID:[Unusual form of genital malformation with aplasia of the right kidney]. 93 22

Six cases of uretero-vaginal fistula are presented. Five patients developed this complication after gynaecological surgery and one after Caesarian section. Constant urinary incontinence combined with normal voiding is typical of this lesion. Excretory urography revealed a stricture in the distal part of the ureter in 5 cases, while in one patient the urographic findings were normal. Accumulation of contrast medium in the vagina was seen on urography in 2 patients. Surgical correction is the treatment of choice, and all patients were successfully treated by resection of the distal part of the ureter with reimplantation of the ureter into the bladder.
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PMID:Uretero-vaginal fistula. 102 Sep 7

Contribution of one case of supernumerary kidney with ureter ectopically opened to vagina associated to horseshoe kidney. Supernumerary kidneys are extremely unusual entities, there being only about 70 cases described in the international literature. This is the first case where it is found associated to horseshoe kidney.
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PMID:[Supernumerary kidney with ectopic ureteral opening to the vagina associated with horseshoe kidney]. 128 24

In order to understand the pathology of incontinence, it is important to investigate urinary symptoms, urological and neurological examinations and urodynamics. There are two kinds of incontinence. One is true incontinence in which urine passes through urethra, and the other is false incontinence due to the ectopic opening of the ureter, for example to the vagina. The former includes stress incontinence, urge incontinence, reflex incontinence, overflow incontinence and total incontinence. Stress incontinence occurs with the sudden increase of abdominal pressure such as cough, running and exertion. The cause of stress incontinence is thought to be weakening of pelvic floor muscles after delivery or aging. In these patients, the bladder base and urethra move downwards and backwards, which make the posterior vesico-urethral angle more than 120 degrees. Treatment of stress incontinence includes pelvic floor exercise, administration of alpha-stimulants which increase the tonus of the internal sphincter and surgery to elevate the urethra. Urge incontinence is observed when detrusor instability occurs. It is also seen in patients with neurological diseases such as multiple cerebral infarction or with benign prostatic hypertrophy (BPH). Treatment of urge incontinence includes administration of anticholinergics to decrease bladder hyperreflexia. Reflex incontinence is seen in patients with spinal cord disorders. It occurs due to reflex contraction of detrusor and the treatment involves administration of anti-cholinergics. Overflow incontinence is seen in patients with voiding difficulties due to BPH. It occurs when residual urine increases and when the intravesical pressure exceeds urethral pressure on body movement. Treatment for this is intended to improve voiding difficulties. Total incontinence occurs when total sphincter function is damaged.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[The pathology and treatment of incontinence]. 159 84

Total Hysterectomy has been until non performed by extracervical "enucleation" of the fascia of the uterine corpus with amputation of the vagina. The new method leaves the extrafascial highly vascularised vascular stem, the corresponding nerves and the topography of the ureter untouched. It is limited to an intrafascial cylindriform enucleation of the cervix. The diameter of the cervical cylinder can be determined beforehand by vaginal sonography. Punching-out is effected from a new instrument C.U.R.T. (= calibrated uterine resection tool) of 10-20 mm diameter. A cervicohaemostaser provides for safe transvaginal haemostasis in the residual cervix. The transvaginal sexual sensations of the patient are not impaired due to the fact that the cardinal ligaments are preserved as well as the nerve supply of the cervical fascia. Suspension of the cervical fascia at the supporting ligaments of the uterus can be performed in an ideal manner. Pelviscopic extirpation of the uterus is done in the classical way used in abdominal hysterectomy with ligature and suture. Morcellated cylinders of 2-3 cms in diameter, of the cervix and corpus uteri and even of myomas up to the size of a child's head, will suffice for relevant histological examination. The physical stress to which the patient is exposed is about the same as in routine surgical pelviscopy. The abdominal space remains practically unopened in pelviscopic transabdominal hysterectomy. Pelviscopic transabdominal hysterectomy with and without adnexae according to the CASH technique corresponds to surgery performed with a minimum of invasiveness. It is fully sufficient as regards cancer prophylaxis with respect to cervical or endometrial cancer.
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PMID:[Hysterectomy via laparotomy or pelviscopy. A new CASH method without colpotomy]. 183 98


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