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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One hundred and twelve patients with evaluable genitourinary tumors were treated with cis-diamminedichloroplatinum (II) as a single agent under multi-institutional clinical trials. Most patients had extensive prior therapy. Of 30 patients with testicular tumors, 5 complete responses (16.7%) and 15 partial responses (50.0%), of 29 patients with bladder carcinoma, 2 CR (6.9%) and 7 PR (24.1%), of 34 patients with prostatic carcinoma, 6 PR (17.6%), and of 10 patients with pelvis and ureter carcinoma, 1 CR and 3 PR were obtained respectively. No responder was seen in eight patients with renal cell carcinoma and in one with urethral carcinoma. Adverse reactions were similar to those already reported including gastrointestinal reactions, nephrotoxicity and myelosuppression. Ototoxicity, peripheral neuropathies and transient elevation of GOT-GPT levels were occasionally encountered. Cis-diamminedichloroplatinum (II) appears to be highly active as a single agent in the treatment of advanced genitourinary tumors.
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PMID:[Phase II study of cis-diamminedichloroplatinum (II) in genitourinary cancer]. 676 7

An unusual case of localized amyloidosis of the ureter is described and a review of the 12 previously reported cases is presented. No case had been diagnosed prior to surgery. Loin pain, with or without haematuria, associated with a sterile pyuria and an abnormal pyelogram were the commonest clinical signs. In the case reported an incidental small renal cell carcinoma was also present and the association of amyloidosis and neoplasia is discussed.
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PMID:Localized amyloid of the ureter--case report and review of the literature. 688 3

On 138 patients with radiologic filling defects in the ureter and renal pelvis lavage cytology was done. With this method it was possible to recognize clearly 39 of 47 urothelial tumors of renal pelvis and ureter (81,3%). Lavage cytology failed in patients with hypernephroma. Severe cellular atypias could be seen in patients with urolithiasis and inflammation. The diagnostic reliability of lavage cytology with urothelial tumors of renal pelvis and ureter is far greater than that of exfoliative urinary cytology and reaches results as good as those from brush biopsy.
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PMID:[Lavage-cytology of the renal pelvis and ureter with special reference to tumors (author's transl)]. 704 57

Autopsy records of renal adenocarcinoma cases were analyzed to investigate the mode of metastatic spread in instances of a tumor thrombus in the renal vein and/or vena cava. In this series of 1,828 cases 137 (7.5 per cent) had a tumor thrombus. Analysis revealed no significant differences in the incidence of the tumor thrombus between sexes or sides of primary renal involvement, or whether nephrectomy had been performed. The cases with a tumor thrombus showed higher frequencies of metastases in the liver, hepatic hilar lymph nodes and ureter, while metastases in the bones, contralateral kidney and brain were less frequent. The results suggest that bypass routes or lymphogenous spread of the tumor might be facilitated in some cases with a tumor thrombus.
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PMID:Distant metastasis of renal adenocarcinoma in patients with a tumor thrombus in the renal vein and/or vena cava. 706 23

Muscle coat specimens from human calices, renal pelvis, pelvi-ureteric junction, upper, middle and lower ureter segments were examined under an electron microscope. These specimens were taken from 8 patients who had undergone nephroureterectomy: 6 for localized renal carcinoma and 2 for papillary tumor of the pelvis. Two types of smooth muscle cells were observed, "typical" muscle cells and "special" muscle cells. The latter are rich in agranular endoplasmic reticulum, have few myofilaments and are interconnected in numerous, extended, peculiar contact areas. The ratio between these two types of muscle cells differs as also does their innervation between the various segments examined. On the basis of our findings we propose that the "special" muscle cells perform a "pacemaking" function.
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PMID:Ultrastructure of the urinary tract muscle coat in man. Calices, renal pelvis, pelvi-ureteric junction and ureter. 720 55

The authors present a case of ureteral metastasis which appeared in the ureter stump after a nephrectomy as a result of an adenocarcinoma of the kidney. They stress the infrequency of this metastatic location. They present a series of considerations concerning the diagnostic doubts arising in connection with the kidney neoplasia which the patient presented, in spite of a complete, urological, physical, analytical, radiourographic as well as arteriographic exploration.
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PMID:[Probable metastasis of a hypernephroma, postnephrectomy in ureteral stump]. 744 7

Lavage cytology was done in 101 patients with radiological filling defects in the ureter and renal pelvis. This simple and inexpensive technique is valuable in the preoperative diagnosis of tumors of the ureter and renal pelvis. In our series it was possible to recognize clearly 29 of 36 such tumors (80.5 per cent) through preoperative lavage cytology. No falsely positive diagnoses were made. Lavage cytology failed in 6 patients with hypernephroma. The diagnostic reliability of lavage cytology with urothelial tumors is far greater than that of exfoliative urine cytology and reaches almost equally good results as brush biopsy.
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PMID:Lavage of cytology of the renal pelvis and ureter with special reference to tumors. 745 79

The incidence and mortality rate of urogenital cancers in Japan are both low compared to those in western countries. However, the incidence and mortality patterns of cancer in Japan are currently becoming closer to those of western countries, and the importance of urogenital cancers is increasing. We conducted an analysis of urogenital cancers in Gunma Prefecture. The subjects were newly detected urogenital cancer patients living in Gunma Prefecture diagnosed between 1985 and 1992. Details were as follows: prostate cancer 1411, bladder cancer 1253 (male 937, female 316), renal cell carcinoma 411 (male 287, female 124), renal pelvic and ureter cancer 187 (male 127, female 60) and testicular cancer 162. Incidence rate was calculated by year, district and age, and was expressed per 100,000/year and was adjusted to world population. Regarding the incidence rate per year for males, that of prostate cancer and renal cell carcinoma increased dramatically from 8.3 to 13.6 and from 1.1 to 3.2, respectively. Incidence rate of other cancers in males showed a slight increase or remained almost stable. Incidence rate by year for females showed a slight increase or remained almost stable as a whole. Gunma Prefecture was divided into 10 districts by the range of daily life of people and the incidence rates of prostate cancer, bladder cancer and renal cell carcinoma for each district were calculated. Incidence rate of prostate cancer tended to be higher in the northern parts of the prefecture, while that of bladder cancer showed no detectable trend.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[An epidemiological study of urogenital cancer in Gunma Prefecture]. 786 47

A total of 37 patients with various renal and adrenal diseases underwent laparoscopic nephrectomy, radical nephrectomy and adrenalectomy since July 1991. The underlying diseases included renal calculi, vesicoureteral reflux, ureteropelvic junction obstruction, ureteral stenosis, ectopic ureter, vascular disease, renal cell carcinoma and adrenal tumors. Twenty-nine kidneys (including 5 with renal cell carcinoma) and 5 adrenal glands were removed successfully. Three cases failed because of dense adhesion to the surrounding structures, hemorrhage from the renal vein and hemorrhage from the vena cava, respectively. Of the remaining 34 patients 3 required additional open laparotomy to control bleeding or remove lost calculi. Mean operating time was 265 minutes for nephrectomy, 383 minutes for radical nephrectomy and 199 minutes for adrenalectomy, and mean estimated blood loss was 455 ml., 430 ml. and 80 ml., respectively. Average hospital stay was 10 days for the 31 patients without open laparotomy and convalescence was completed by postoperative day 21. These results indicate that laparoscopic surgery for renal and adrenal disease is a feasible, minimally invasive procedure. In the case of laparoscopic radical nephrectomy, however, longterm followup is necessary to confirm the efficacy.
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PMID:Laparoscopic nephrectomy, radical nephrectomy and adrenalectomy: Nagoya experience. 796 50

Renal cell carcinoma uncommonly metastasizes to the ureter, with only rare reports of metastatic lesions developing in the contralateral side. Recently at our institution, two patients presented with contralateral ureteral metastases from a primary renal adenocarcinoma; one was synchronous and the second metachronous. Following extensive metastatic evaluations, both lesions were believed to be solitary metastases. The involved ureters were managed with total ureterectomy and construction of an ileal ureter. We report these two cases and review the literature.
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PMID:Metastatic renal cell carcinoma to the contralateral ureter. 804 8


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