Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of bilateral, symmetric and synchronous cancer of the ureter. Diagnose, therapy and development are described. Finally follow the considerations concerning pathogenesis.
 ...
PMID:[Bilateral, synchronous and symmetric cancer of the ureter (author's transl)]. 77 11

Simple ureteroceles discovered in adults on excretory urography have long been regarded as congenital anomalies, usually innocuous. Pseudoureteroceles are acquired dilatations of the submucosal portion of the distal ureter that mimic simple ureteroceles. The authors compared 5 pseudoureteroceles and 13 simple ureteroceles and found that the former were distinguished by asymmetry of the dilated ureteral lumen, moderate to severe obstruction of the upper tract, and evidence of an acquired cause such as a calculus or abnormal vesical mucosal pattern. The distinction is important, since most pseudoureteroceles were related to malignancy involving the bladder.
 ...
PMID:Ureteroceles vs. pseudoureteroceles in adults. Urographic diagnosis. 83 Mar 58

Data on the occurrence of endemic nephropathy (EN) and urinary tract and other cancers in an endemic region of Vratza district, Bulgaria, for the years 1965-1974, are presented. In endemic villages a high incidence of urinary tract tumours, affecting in particular the renal pelvis and ureter, closely correlated with the EN incidence and mortality rates. In the villages with high and moderate EN incidences urinary tract tumours are the most common neoplasms. They account for 25% of all tumour sites in males and 30% in females. In hyperendemic villages age-adjusted incidences in EN and urinary tract tumours were 506/10(5) and 104/10(5) in females, and 315/10(5) and 89/10(5) in males respectively. EN mortality in these villages accounted for over 40% of all deaths in females and about 30% in males. Both diseases displayed peculiar geographic clustering. Females and middle-aged persons were most often affected. Urinary tract neoplasms were often multiple and nearly 90% of them originated in the uro-epithelium. In endemic and non-endemic villages of the region studied, the frequency and pattern of non-urinary tract cancers were rather similar, with statistical values close to those of the rural population of Vratza District and Bulgaria as a whole.
Int J Cancer 1977 Jan
PMID:Geographic correlation between the occurrence of endemic nephropathy and urinary tract tumours in vratza district, Bulgaria. 83 16

A total of 481 cases of retroperitoneal fibrosis (RPF) presented in the literature have been reviewed. Ten additional cases from this hospital have been added. One etiological factor, methysergide, has been implicated in 12.4 percent of cases, but the majority remain unexplained. Characteristically, the patient will be male (2:1 ratio), in his 50's (30.9 percent), with vague lower back pain (34.2 percent) or possibly flank pain (34.0 percent). Physical examination usually will be unrevealing. The patient's serum chemistry probably will show some degree of azotemia (55.4 percent) and perhaps anemia (13.6 percent). The intravenous pyelogram characteristically shows bilateral hydroureteronephrosis (67.6 percent) or unilateral hydroureteronephrosis (20.3 percent) associated with medial deviation of the ureter due apparently to external compression of the ureter. Methysergide should be discontinued if implicated. Laparotomy for ureteral compression characteristically will reveal a dense, rubbery plaque in the retroperitoneum. Generous frozen section biopsies show fibrosis, usually with some chronic inflammation, suggestive of RPF. Careful inspection of retroperitoneal nodes and liver may reveal the presence of malignancy in 7.9 percent of patients. In the absence of malignancy, the ureters should lyse fairly freely and peristasis may return. If no malignancy is present on permanent sections of biopsy material, the patient can be given a fairly optimistic prognosis (cumulative mortality rate, 9 percent). Suboptimal improvement probably is an indication for steroid therapy and surgical re-exploration may become indicated. In these cases further search for malignancy should be undertaken.
 ...
PMID:The clinical significance of retroperitoneal fibrosis. 84 63

Ureteral abnormalities following excision of the rectum are similar to those found in retroperitoneal fibrosis. Their frequency is surprisingly high (45 out of 53 patients under close supervision approximately equal to 85%). Medial deviation of the lumbar ureter was regularly encountered on one or both sides (most pronounced at L5). Narrowing of the lumen occurred in 31 patients combined with impaired urinary excretion in 12 cases, among these hydronephorosis in 2 cases. As reason for this secondary retroperitoneal fibrosis the retarded healing of the sacral cavity has mainly to be considered. Furthermore, the surgical trauma itself seems to be of importance in this regard. Following surgery for cancer differential diagnosis of ureteral abnormalities should include malignant retroperitoneal infiltration.
 ...
PMID:[Secondary retroperitoneal fibrosis of scars following rectum exstirpation]. 86 75

A study of three families living in villages with endemic nephropathy (EN) in Vratza district, Bulgaria, revealed 9 members with urinary system tumors (UST), 7 with UST and EN, and 7 with EN. Most cases were registered from 1962 to 1976. The predominant form was transitional cell neoplasms of the kidney pelvis and ureter in patients 40-60 years old. In about 40% of the patients more than one site in the urinary system was involved. One ovarian carcinoma was also registered in these families during this period. Persons related by marriage and coming from nonendemic families and villages were also affected by both diseases. In other branches of the three families living in other households or villages, only one case of EN was found.
J Natl Cancer Inst 1977 Nov
PMID:Families with multiple cases of urinary system tumors: brief communication. 90 2

An analysis of 5 patients with an acquired dilatation of the distal ureter, simulating a simple ureterocele, is herein reported. Radiologically, pseudoureteroceles are more likely to be associated with ipsilateral upper tract obstruction and have asymmetric intravesical dilatation. The urologist should be aware of this urographic deformity, for the majority of pseudoureteroceles are related to malignancy involving or invading the bladder.
 ...
PMID:Pseudoureterocele: a uroradiologic entity. 91 47

A retrospective analysis of 74 cases of transitional cell carcinoma of the renal pelvis and ureter treated at this institution over the past 30 years is presented. When nephrectomy alone or incomplete nephroureterectomy was performed, subsequent transitional cell carcinoma developed in 30% of the ureteral stumps. Subsequent bladder carcinoma occurred in 25% of the patients with primary upper urinary tract carcinoma. The type of initial surgery performed did not appear to influence this incidence of subsequent bladder tumors. Contralateral upper urinary tract carcinoma developed in only one patient. When nephroureterectomy is performed for carcinoma of the renal pelvis and ureter, a cuff of bladder that includes the ureteral orifice should be removed to obviate recurrent disease in the ureteral stump. Since single-incision nephroureterectomy did not include the intramural ureter in 50% of the cases in which it was performed, a second incision may be required for adequate exposure.
Cancer 1976 Nov
PMID:Recurrent urothelial tumors following surgery for transitional cell carcinoma of the upper urinary tract. 99 Nov 30

An attempt was made to produce damage to the ureter of the dog with external irradiation in the high therapeutic ranges in the absence of surgery or cancer. No significant changes were apparent on excretory urography and only minimal changes were seen on histologic study. In another series of dogs, one ureter was reimplanted before the administration of maximal irradiation and the other ureter was reimplanted after the irradiation. The reimplanted ureter tolerated later irradiation very well. The postirradiated ureter tolerated similar surgery very poorly.
 ...
PMID:Irradiation injury to the ureter and surgical tolerance. An experimental study. 99 76

Fourty-one patients with primary invasive carcinomas of the ureter were seen at Memorial Hospital from 1947 to 1972. Overall survuval patterns were similiar in 19 patients with and 22 patients without prior or concomitant urothelial cancers elsewhere in the urinary tract, with 5-year survival rates, as estimated by the product-limit methos, of41% for both groups. Prognosis was determined primarily by anatomical stage of ureteral cancer. In 11 Stage A (submucosal) patients, 7 Stage B (muscular), 12 Stage C (periureteric fat), and 9Stage D (extraureteral), the similarly estimated 5-year survival rates were 91%, 43%, 23%, and nil, respectively. None of Stage A cases had metastases for periods ranging from 5 to 11 years after surgery alone. Seventy-eight percent of patients with more advanced stages died within 3 years of treatment, withmetastases mainly in pelvic and para-aortic lymph nodes.
Cancer 1975 Jun
PMID:Primary carcinoma of the ureter: a prognostic study. 114 96


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>