Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The oral administration of N-bis(2-hydroxypropyl)nitrosamine (DHPN) in drinking water induced lung tumors in high incidence in rats at 25 weeks. Histologically, they were adenoma, adenocarcinoma, squamous cell carcinoma, and combined squamous cell and adenocarcinoma. Metastases of adenocarcinoma were observed in regional lymph nodes. The development of tumors in other sites was seen in the liver, thyroid, kidney, ureter, urinary bladder, and pancreas. The incidence of lung tumor was distinctly higher than that of other sites. These results indicate that the target organ of DHPN was the lung and that oral administration of this chemical carcinogen was responsible for the development of lung carcinomas in rats.
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PMID:Lung carcinomas induced by oral administration of N-bis(2-hydroxypropyl)nitrosamine in rats. 102 5

The patient was a 63-year-old women who visited our hospital with the chief complaints of swelling, chills, fever and right lumbago. Fifteen years ago, she received surgical exploration for right renal stones at another department of urology. A large, soft and round kidney was palpable from the right upper quadrant of abdomen to the right lower abdomen. The parenchyma of the right kidney was thinned and inside the kidney there was a huge amount of yellowish mucin. The histological diagnosis was mucin-producing cyst-adenoma (borderline malignancy) of the renal pelvis and ureter. Mucin-producing cystadenoma of the renal pelvis and ureter origin was very rare, and only 4 similar cases to our patient were so far reported.
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PMID:[Mucin-producing cystadenoma (borderline malignancy) of the renal pelvis and ureter. A case report]. 220 48

A case of multicentric papillary adenocarcinoma arising in the renal pelvis and proximal ureteral mucosa of a 35-year-old man is presented. The left nephrectomy specimen demonstrated multiple, fungating, papillary tumors. The largest tumor measured 10 X 9 X 6 cm and invaded the renal parenchyma. Smaller tumors with long stalks were found. Microscopically, the papillary fronds of each neoplasm were lined by a single layer of cuboidal to low columnar epithelium admixed with a few areas of invasive tubular adenocarcinoma. The adjacent pelvic mucosa was the site of cuboidal epithelial metaplasia. The ultrastructure of both the papillary tumor and the pelvic mucosa suggested that they originated from the nonmucigenic metaplastic epithelium with a partial similarity to the lining of the proximal convoluted tubule. The growth pattern and the multicentric development of this unusual neoplasm suggest that this is a case of the malignant counterpart of the nephrogenic adenoma in the kidney and ureter, and reflect a biologic behavior corresponding to ordinary urothelial papillary tumors.
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PMID:Multicentric papillary adenocarcinoma of the renal pelvis and ureter. Report of a case with ultrastructural study. 317 58

Nephrogenic adenoma is a rare, benign lesion of the bladder, occurring as an epithelial response to infection or trauma. Characteristically, it presents as a papillary lesion resembling a low grade, low stage transitional cell carcinoma. Although usually occurring in adults, there have been 5 reports in children, in whom the adenoma occurred following either surgery or localized inflammation. We report on 2 additional children with nephrogenic adenoma, including one who presented with a bladder mass and total occlusion of the ipsilateral ureter, while in the other it was found incidentally during closure of a vesicovaginal fistula. Successful treatment consisted of transurethral resection and low dose suppressive antibiotics. Nephrogenic adenoma, while rare in children, appears to be a uroepithelial metaplastic response to trauma or inflammation and is treated best by conservative management.
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PMID:Nephrogenic adenoma in children. 396 88

A 44-year old women with 8 years of analgesic abuse developed bilateral ureteral stenosis with urine congestion and manifestations of renal insufficiency. The resected parts of the ureters were affected by chronic productive inflammation with pronounced capillarosclerosis characteristic of analgesic abuse and largely responsible for the stenosis of the lumina. In addition there was a nephrogenic adenoma in the left ureter, so far almost exclusively described in the urinary bladder and prostatic urethra. Its relation to the analgesic abuse is under discussion.
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PMID:Chronic sclerosing ureteritis and nephrogenic adenoma of the ureter in analgesic abuse. 408 Jun 41

Concurrent primary renoparenchymal or renal pelvic neoplasms of different histology in the same kidney appear to be unusual. We herein report on a 75-year-old man in whom a tiny renal adenoma, a transitional cell carcinoma of the renal pelvis, ipsilateral ureter papillomas and transitional carcinoma of the urinary bladder were found. The clinicopathologic findings of this patient as well as the oncogenesis of renal tumours are discussed.
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PMID:Renal adenoma incidentally found in removed kidney in a patient with transitional cell carcinoma of the renal pelvis. 408 36

A urodynamic study of patients with prostatic adenoma or other types of cervicoprostatic obstructions demonstrate that ureteral stasis is not a consequence of a direct compression of the intramural ureter by the adenoma but is secondary to dynamic disturbances.
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PMID:Ureteral stasis in cervicoprostatic obstructions. 615 59

Nephrogenic adenoma a rare bladder, ureter, or urethral lesion, is of disputed pathogenesis, metaplastic and congenital etiologies both being implicated in its development. Since light and electron microscopy have been unable to fully resolve the lesion's pathogenesis, the authors used biotinylated lectins as probes and avidin-biotin peroxidase complex (ABC) as a visualant to study cases of nephrogenic adenomas and compared their lectin binding patterns with those of normal transitional epithelium, human embryonic kidneys, and cases of cystitis cystica and glandularis and squamous metaplasia of the bladder in an effort to clarify this issue. Only the epithelial lining of the luminal surface and tubuli in nephrogenic adenoma and tubules in embryonic kidney exhibited free PNA receptor sites. The striking staining similarities between the epithelial components of nephrogenic adenomas and mesonephric and metanephric tubules complement previous findings concerning the origin of nephrogenic adenoma.
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PMID:Nephrogenic adenoma and embryonic kidney tubules share PNA receptor sites. 620 99

We report a case of nephrogenic adenoma in the left ureter. The patient presented with lumbago on the left side. A small calculus was incarcerated in the left ureter 4 cm. from the ureteropelvic junction and an adenoma, which resembled histologically the renal tubules, was observed in the ureter. A search of the world medical literature revealed 58 cases of nephrogenic adenoma, although only 1 case in the ureter has been reported previously.
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PMID:Nephrogenic adenoma of the ureter. 636 52

This report presents three cases of colon tumors which developed after an ureterosigmoidostomy. In a checkup, four years after the operation, an inflamed polyp was found in one patient. The second patient developed an adenoma in the section of the colon where the ureter had been implanted. The last patient died of adenocarcinoma of the colon 26 years after her operation. Possible reasons for the development of the tumors, specifically the cancerous ones, are discussed. The risk of developing colon carcinoma is 500 times higher in those who have had an ureterosigmoidostomy than in healthy people. In the case that the ureters are rediverted the section of the colon where they were previously attached must be excised; since there is a strong possibility of cancerous development. To detect the early development of tumors in the colon, we suggest that patients have their stool tested for blood at regular intervals starting 3 years post operatively. If no problems arise barium enema and coloscopy are recommended every five years.
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PMID:[Tumors of the colon following ureterosigmoidostomy]. 668 45


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