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Query: UMLS:C0403608 (ureter)
 9,655 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of a forty-five-year-old woman with fused kidneys and intercommunicating pelves drained by a single ureter crossing the midline is reported. A review of the literature is presented.
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PMID:Combined renal and pyelic fusion with crossed ectopia of single ureter. 353 95

We present a case of primary ureteral carcinoma in the duplicated renal pelvis and ureter diagnosed by transurethral uretero-renoscopy. The case was of a 78-year-old man with the complaint of sudden asymptomatic macrohematuria. An excretory urogram strongly suggested the presence of duplication of the right collecting system, and cystoscopy revealed a gross hematuria from the right ureteral orifice. A retrograde ureteropyelogram revealed incomplete duplication of the right renal pelvis and ureter fused at about the ureter crossing over the iliac vessels, and a polyp-like filling defect in the lower segment of duplicated ureter at about 4 cm from the fusion of the ureters. Transurethral uretero-renoscopy was employed to investigate the filling defect, and a papillary tumor extended into the lower segment of duplicated ureter was revealed. Tumor was resected by a rigid operating instrument under transurethral uretero-renoscopy. The pathological diagnosis was grade I-transitional cell carcinoma of the ureter, so that right total nephroureterectomy with partial cystectomy was carried out subsequently. Surgical specimen after right total nephroureterectomy with partial cystectomy showed no other tumor in the pelvis or ureter macroscopically, and histopathological studies of surgical specimens were no evidence of malignancy. We believe that transurethral uretero-renoscopy significantly increases the diagnostic accuracy in determining the nature of upper urinary tract lesions, and this procedure is indispensable in the diagnosis of ureteral tumors. The present case was the 7th case of primary ureteral carcinoma in the duplicated renal pelvis and ureter in the Japanese literature.
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PMID:[A case of primary ureteral carcinoma in the duplicated renal pelvis and ureter diagnosed by transurethral uretero-renoscopy]. 372 47

French research on Latimeria published before 1972 is first briefly recalled. After the Anglo-Franco-American Expedition of 1972, the material obtained enabled us to focus attention on the histology of the kidney and ureter and on ultrastructural aspects of the postnatal gland. Ovarian eggs of unusual volume have been collected, measured and weighed. Kinematic analysis of the intracranial articulation was carried out in 1973 on a frozen coelacanth that reached Paris. Studies in 1974 of a 41 cm specimen, the smallest known at that time and estimated to be 3 1/2 years old, showed that the brain still filled the cranial cavity: thus, it is later that allometric growth of the cranial cavity relegates the brain to the posterior part of the skull. In the same specimen, radiographed after injection with colloidal barium oxide, we were able to specify the likely role of the contractile organs fused to the branchial arteries: they may serve to regulate arterial pressure in the head during sudden movements of the jaws, and thus of the anterior cranium, as prey is captured. Lastly, the structural characteristics of the teeth, scale denticles, and spines on the lepidotrichia have been revealed, as also has the lamellar structure of the scales, in which there is a crossed orientation of the fibres in the different layers.
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PMID:[Review of French literature on Latimeria, notably since 1972]. 610 97

We studied 58 case reports of patients with supernumerary kidneys to determine the morphology, vagaries and embryogenesis of this rare and poorly documented anomaly. The supernumerary kidney usually was located caudal to the ipsilateral kidney when subserved by a bifid ureter and cranially when the ureters were separate. The Weigert-Meyer law for duplex fused kidneys was obeyed by the supernumerary ureter in most fully documented cases of double ureters. Pathologic conditions of the upper urinary tract occurred in more than 50 per cent of the patients with a bifid system, who were prone to have hydronephrosis and calculous disease, and with a double system, who were prone to have complications resulting from supernumerary ureteral ectopia. Double tails to the nephrogenic cords, each induced by a branch of a bifid bud or by 1 of 2 separate buds as opposed to tandem inductions of a single metanephros, were regarded as the probable embryogenesis.
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PMID:Supernumerary kidney. 688 91

The authors studied hydronephrosis characteristics for horseshoe kidney in 170 patients aged 15-70. Basing on anatomic and functional features and urethral condition in each patient 136 operative interventions on one or two parts of the fused kidney in 125 patients were conducted. 26 heminephrectomies were carried out in hydronephrosis stage III, pyonephrosis and acute purulent focal pyelonephritis. 110 stage I-II hydronephrosis patients underwent an original reconstructive combined surgery on the fused kidney ending in formation of two separate organs. High incidence of hydronephrosis in horseshoe kidney against that in normal kidney (64 and 7%, respectively) and not infrequent bilateral involvement (63%) can be explained by anomalous structure of the organ conducive to obstruction of the urinary tracts. In 136 surgical cases the obstruction was due to: peripelvic compression of the ureter above the isthmus of the kidney (128 cases), high branching of the ureter from the renal pelvis with formation of the "spur" (114 cases), periurethritis and the fixed peripelvic ureteral kink by the adhesions (64 cases), congenital stricture of the peripelvic ureter (42 cases) or its compression by the accessory vessel (12 cases). To correct these abnormalities, it is reasonable to employ reconstructive surgery proposed by E. M. Shimkus. The procedure implies the isthmus resection with renal segment part, resection of the lower calyx, pelvic plasty according to Anderson-Hines technique, pyelolithotomy and nephropexy. This surgery abolishes all the underlying causes of fused kidney hydronephrosis and reestablishes urodynamics. It secured positive results by 2-28-year follow-up in 95% of the patients and is recommended as a method of choice.
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PMID:[Hydronephrosis in a horseshoe kidney]. 794 Nov 67

Leucine arylamidase (LAA) excretion in circadian urine of 79 patients suffering from nephroureterolithiasis was measured before and after the session of remote impulse lithotripsy (RIL) to investigate the effect of the impulse on renal function. The stones were localized in the calyces, pelvis and upper third of the ureter. The patients were divided into 2 groups: 43 patients with noncomplicated nephroureterolithiasis (group 1) and 36 patients with complicated one including 12 subjects exposed to the second RIL (group 2). The enzyme excretion was significantly reduced in group 1 patients. Its activity recovered in group 1 within 6-7 days, in group 2 for 10-14 days. After the second RIL procedure LAA activity in the urine enhanced more rapidly, especially in group 2 patients. In calyceal, intrarenal pelvic and fused kidney location of the stone, LAA activity got more elevated than in the extrarenal pelvis or in the upper third of the ureter. It is demonstrated that RIL exhibits a short-term effect on the kidneys which depends on the presence of inflammation, the number of sessions, stones location and the number of impulses.
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PMID:[The effect of remote-controlled shock-wave lithotripsy on kidney function]. 816 Mar 15

Metanephric mesenchyme gives rise to both the epithelial cells of the nephron and the stromal cells of the mature kidney. The function of the stroma. in kidney morphogenesis is poorly understood. We have generated mice with a null mutation in the Winged Helix (WH) transcription factor BF-2 to examine its function during development. BF-2 expression within the developing kidney is restricted to the stromal cell lineage. Homozygotes die within the first 24 hr after birth with abnormal kidneys. Mutant kidneys are small, fused longitudinally, and rotated 90 degrees ventrally. Histological examination reveals a smaller collecting system, numerous large condensations of mesenchyme, and a decrease in the number of nephrons. Using molecular markers we show that induction and condensation of the nephrogenic mesenchyme occurs normally in mutant. The disruption of BF-2 reduces the rate of differentiation of the condensed mesenchyme into tubular epithelium, as well as the rate of growth and branching of the ureter and collecting system. Our findings demonstrate that BF-2 and stromal cells have essential functions during kidney morphogenesis. Furthermore, they suggest that BF-2 controls the production, by the stroma, of signals or factors that are required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system.
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PMID:Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. 866 31

A 32-year-old man consulted Osaka National hospital with chief complaints of dysuria and macrohematuria. DIP and CT revealed that the right kidney deviated to the lower pole of the left kidney and they fused together. The right ureter crossed over the supine. The calcified shadow existed in the lower end of the left ureter with cobra head image. He had no external anomalies. Under diagnosing crossed fused kidney (inverted L shaped) complicated the left ureterocele with a stone, transurethral incision of ureterocele (TUI) was performed. We made transverse incision and extracted stone, 7 mm in size (calcium oxalate 96% and calcium phosphate 4%). Three months later after the operation, IVP, CG and VCG revealed the down-sized ureterocele and no VUR. Crossed renal ectopia complicated many anomalies about 50%. Among them anomalies of the urinary tract was most frequent about 30%. But crossed renal ectopia with ureterocele wasn't reported so far in Japanese literature.
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PMID:[A case of crossed fused kidney with simple ureterocele]. 1065 64

A 5-year-old girl with a rare anomaly of a single system ectopic ureter draining into the mesonephric duct cyst and ipsilateral crossed fused kidney is presented. Both ureters were catheterized and three dimensional (3-D) images of the urinary tract were reconstructed with helical computed tomographic (CT) data. A mesonephric duct cyst, the right ureter draining into the cyst and an ectopic orifice were well depicted with these images, especially with inferior projection images. 3-D display of helical CT data with a retrograde contrast study is a promising method of obtaining anatomical detail of an ectopic ureter.
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PMID:[Crossed fused kidney with ectopic ureter: a case report]. 1080 77

The myelin basic proteins (MBPs) are a family of polypeptides that are predominantly expressed in the nervous system where they play a major role in myelination. We have generated four lines of transgenic mice carrying a transgene in which 1.34 kb of the 5'-flanking sequence of the mouse MBP gene was fused upstream of the coding region of the Escherichia coli lac Z gene in order to investigate developmental and tissue-specific expression of the MBP gene. Expression of both the lacZ transgene and the endogenous MBP gene followed a common developmental pattern in mouse brain. Transgene expression was detected in primary oligodendrocytes, but not in type 2 astrocytes. In addition, the lacZ gene product was expressed in epithelial cells of certain nonneural tissues, namely kidney, epididymis, ureter, and seminal vesicles. The ectopic expression of the transgene was associated with the development of DNase I hypersensitive sites at the site of insertion which was found to be within the intron 1 region of the endogenous MBP gene. The results reported here strongly suggest that the 1.34-kb 5'-flanking region of the MBP gene contains cis-regulatory elements that confer developmental regulation of the MBP gene, although this region appears to lack elements that restrict its expression to the nervous system.
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PMID:The specificity of the myelin basic protein gene promoter studied in transgenic mice. 1168 80


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