Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0393754 (
HSA
)
2,996
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The synthesis of a novel PS conjugated with bovine and human serum albumin (BSA and
HSA
) and a monoclonal antibody anti-
CD104
is reported, as well as their biological potential against the human bladder cancer cell line UM-UC-3. No photodynamic effect was detected when the non-conjugated porphyrin was used. Yet, when it was coupled covalently with the mAb anti-
CD104
, BSA and
HSA
, the resulting photosensitizer conjugates demonstrated high efficacy in destroying the cancer cells, the mAb anti-
CD104
efficacy overruling the albumins.
...
PMID:Porphyrin conjugated with serum albumins and monoclonal antibodies boosts efficiency in targeted destruction of human bladder cancer cells. 2451 83
