Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0393754 (
HSA
)
2,996
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In this work, a novel and convenient strategy for synthesis of a well-defined polymer containing both aldehyde and ferrocene functional groups by grafting
4-hydroxybenzaldehyde
and ferrocenecarboxylhydrazide onto linear poly (vinylbenzyl chloride) was developed. The designed polymer film (polymer CAF) could be used as a new support matrix for fabrication of a label-free electrochemical immunosensor with high sensitivity, good stability and repeatability. With human IgG as an analyte model, the proposed electrochemical immunosensor showed a linear concentration range from 0.1 to 20ngmL
-1
with a detection limit of 0.07ngmL
-1
(S/N=3). Moreover, interfering proteins including
HSA
, IgM, and IgE were added into the analyte, the developed immnnosensor can detect human IgG with high specificity.
...
PMID:A label-free electrochemical immunosensor based on a new polymer containing aldehyde and ferrocene groups. 2810 62
