Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392680 (shortness of breath)
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Human Gene/Protein
SS18/SSX2 fusion 11.0
DPCR1 10.0
Metalloelastase 9.8
odd-skipped related 1 9.4
succinate dehydrogenase complex subunit B 9.0
OSR2 8.8
RecA-like protein 8.6
V5-6 8.0
SLC34A2 7.8
IFT80 7.6
DNase X 7.6
Mulibrey nanism 7.5
RMI2 7.5
lifeguard 7.5
GCNT2 7.4
ETFA 7.4
TRIM37 7.3
Mast cell tryptase 7.3
CYB5R3 7.3
KLHL3 7.2
CMIP 7.1
BCORL1 7.1
Napsin-A 7.1
Ewing sarcoma breakpoint region 1 7.1
TTR protein 7.0
nrf 7.0
TBX4 7.0
SLC12A1 6.9
SPA2 6.8
voltage gated potassium channel 6.8
PELP1 6.7
NADE 6.7
Golgi alpha-mannosidase II 6.6
Ela 6.6
SSX1 6.6
ZIC3 6.6
MAPA 6.6
soxB 6.5
SLC29A3 6.5
metalloelastase 6.4
phosphodiesterase 5A 6.4
METS 6.4
PEF 6.4
ZFP36L2 6.3
P2Y13 6.2
PRNT 6.2
MHC class I protein 6.1
SMPD1 6.1
SF4 6.1
PTK7 6.1
double-stranded RNA adenosine deaminase 6.1
MYLK 6.1
UAP 6.1
PASP 6.0
She 5.9
Troponin T 5.9
placental-like alkaline phosphatase 5.9
napsin A 5.8
atopic) 5.7
TLE1 5.7
por 5.6
SARS 5.6
Acid sphingomyelinase 5.6
MUM-1 5.6
FEV 5.5
URI 5.5
OSCAR 5.5
troponin I 5.5
OSR1 5.5
ADAS 5.5
SRB 5.5
LITAF 5.4
COPD 5.4
MLK3 5.4
ASAP 5.4
SYT 5.3
Emerin 5.3
ABCA3 5.3
ASMA 5.3
PSN 5.3
more...
Disease
Cytomegalovirus pericarditis 12.6
Malignant chylothorax 12.6
Cervical herpes zoster 12.6
combined thymoma 12.6
Pleurisy/pleural effusion 12.6
Vanishing lung 11.4
Bronchocutaneous fistula 11.0
Chronic atelectasis 11.0
Cricoarytenoid joint arthritis 11.0
Bullous lung disease 10.6
Acute pulmonary histoplasmosis 10.6
Acute alveolitis 10.6
Desmoplastic mesothelioma 10.6
Serous surface papillary carcinoma 10.6
Cardiac fibroma 10.3
Multifocal micronodular pneumocyte hyperplasia 10.3
Giant bullous emphysema 10.3
Tuberculous enteritis 10.3
Nodular sarcoidosis 10.3
Secondary thrombocytopenia 10.3
Pleural endometriosis 10.3
Phagophobia 10.3
Hemorrhagic pleural effusion 10.3
Idiopathic arterial calcification of infancy 10.0
Infantile asthma 10.0
Streptococcus pyogenes pharyngitis 9.8
sinus problem 9.8
Congenital methemoglobinemia 9.7
Roaring 9.6
Intra-abdominal metastases 9.6
Mitral obstruction 9.6
Post-infectious glomerulonephritis 9.6
Laryngeal sarcoidosis 9.4
Pericardial cyst 9.4
Cardiovascular beriberi 9.4
Moraxella infection 9.3
Atypical measles 9.3
Laboratory animal allergy 9.3
Eosinophilic disorders 9.1
DIPNECH 9.1
Pulmonary alveolar microlithiasis 9.1
Renal vasculitis 9.0
Pulmonary congestion 9.0
Flash pulmonary edema 8.9
Catamenial pneumothorax 8.8
Peripheral pulmonary artery stenosis 8.8
Extraskeletal mesenchymal chondrosarcoma 8.8
Mediastinal fibrosis 8.8
Gastropleural fistula 8.8
Cholinergic urticaria 8.7
Aquagenic urticaria 8.7
CDFI 8.6
thymic neoplasm 8.6
Anaphylactoid reaction 8.6
Bronchial wall thickening 8.6
Pulmonary toxoplasmosis 8.6
Tracheopathia osteoplastica 8.5
Atopic disorders 8.4
stage IIIB NSCLC 8.4
Necrotizing sarcoid granulomatosis 8.3
metastatic follicular thyroid cancer 8.3
Stress cardiomyopathy 8.3
Aortitis syndrome 8.3
Diffuse panbronchiolitis 8.2
Eosinophilic pneumonia 8.2
stage IV renal cell carcinoma 8.1
Drug-induced immune hemolytic anemia 8.1
Giant cell carcinoma 8.1
Acute mitral regurgitation 8.1
Acquired methemoglobinemia 7.9
Thymolipoma 7.9
Omental infarction 7.9
Exercise-induced bronchospasm 7.9
allergic sinusitis 7.9
Phlegmonous gastritis 7.9
cervical arthritis 7.9
lung sarcoma 7.9
Pelvic endometriosis 7.8
Pulmonary vein thrombosis 7.8
pleural neoplasm 7.8
more...
Symptom
shortness of breath 12.6
Gait deviation 12.6
Chronic wheezing 11.6
Multiple symptomatology 11.6
Increasing breathlessness 11.6
feeling feverish 11.0
chest tightness 10.2
Upper back pain 10.0
circulatory problem 9.8
Gastrointestinal signs and symptoms 9.8
Neck swelling 9.6
Rhonchi 9.6
radiating back pain 9.6
pleuritic chest pain 9.5
feeling dizzy 9.5
feeling of choking 9.3
calf cramps 9.3
rib pain 9.1
abnormal breath sounds 9.0
burning on urination 9.0
feeling faint 9.0
sinus congestion 8.8
orthopnea 8.8
cold sweats 8.8
non-productive cough 8.8
throat irritation 8.7
wheezing 8.6
Cardiac pain 8.6
productive cough 8.6
pedal edema 8.5
lightheadedness 8.4
Stable angina pectoris 8.4
cracked lips 8.4
Platypnea 8.4
cough 8.2
night sweats 8.2
stuffy nose 8.1
carpopedal spasm 8.1
chest pain 8.0
rales 8.0
difficulty with urination 7.8
Multiple symptoms 7.8
Lung hyperinflation 7.8
feeling sick 7.7
persistent cough 7.7
General symptoms 7.7
Respiratory symptoms 7.6
Acute dyspnea 7.6
exertional chest pain 7.6
vaginal itching 7.5
chronic cough 7.4
nocturnal cough 7.3
Air trapping 7.3
hemoptysis 7.3
stridor 7.3
voice change 7.3
feeling tired 7.3
lassitude 7.2
dry throat 7.2
sore throat 7.1
Ortner's syndrome 7.1
chills 7.1
generalized abdominal pain 7.0
koilonychia 6.9
hoarseness 6.9
cardialgia 6.9
loss of taste 6.8
clubbing 6.8
atypical chest pain 6.7
Spasmodic dysphonia 6.7
presyncope 6.7
jaw pain 6.6
leg edema 6.6
cyanosis 6.6
arm pain 6.6
dyspnea 6.6
dizziness 6.5
tachypnea 6.4
diastolic murmurs 6.4
Sister Mary Joseph's nodule 6.3
more...
Drug
Xopenex 11.6
Fursultiamine 10.3
Fadrozole hydrochloride 9.3
Micronomicin sulfate 8.9
Vanceril 8.9
Tilade 8.5
Terbutaline sulfate 8.3
Histoplasmin 8.1
Zosyn 8.0
Clinoril 7.9
Warfarin sodium 7.2
Regadenoson 7.0
Flunisolide 7.0
1-Deoxynojirimycin 6.9
Bactrim 6.9
Singulair 6.8
Biltricide 6.7
Nedocromil sodium 6.6
Beraprost sodium 6.6
Hyoscyamine 6.3
Relenza 6.3
CDX 6.2
Rasburicase 6.1
Prograf 6.1
Becotide 6.1
Doxapram 5.9
Epoetin alfa 5.9
Ventolin 5.9
Alteplase 5.8
Coumadin 5.8
CDX 5.7
Dalbavancin 5.6
Alteplase 5.6
Trimethoprim-sulfamethoxazole 5.6
Chlorothiazide 5.5
Axitinib 5.5
Alteplase 5.5
Apixaban 5.4
Epoetin alfa 5.3
Zileuton 5.3
Vena 5.3
Vena 5.3
Fondaparinux 5.2
Panitumumab 5.2
Swainsonine 5.2
Diphenhydramine 5.1
Casodex 5.0
Bivalirudin 4.9
Bosentan 4.9
Bosentan 4.8
Tarceva 4.8
Asthma 4.8
Pirfenidone 4.7
Encore 4.7
Rasburicase 4.6
Piperacillin 4.6
Oxacillin 4.6
EMB 4.5
Cidofovir 4.5
GNA 4.5
Prednisolone 4.4
Premarin 4.3
CPZ 4.3
EDR 4.2
Tacrolimus 4.2
Omeprazole 4.2
Salbutamol 4.2
Optison 4.1
Filgrastim 4.1
Erlotinib 4.0
Allergen 4.0
Filgrastim 3.9
Pemetrexed 3.9
Ipilimumab 3.9
Rituximab 3.9
Botox 3.9
Tocilizumab 3.8
Moxifloxacin 3.7
CTA 3.7
PFT 3.6
more...
Enzyme
MSAS 6.7
macrophage elastase 5.4
dissimilatory sulfite reductase 5.4
APS reductase 5.3
DD-carboxypeptidase 5.2
BAL 4.6
CDR 4.6
angiotensin-converting enzyme 2 4.6
NADH-cytochrome b5 reductase 4.5
mannosidase II 4.0
chymopapain 3.9
chymopapain 3.8
sulfite oxidase 3.8
sulfite oxidase 3.7
3C protease 3.6
Hageman factor 3.6
SPT 3.5
CCS 3.4
CPM 3.2
CEP 3.0
creatine kinase 3.0
FAST 3.0
lactic acid dehydrogenase 3.0
ACE 2.9
SPT 2.8
tryptase 2.7
nitrite reductase 2.7
lactate dehydrogenase 2.5
CEP 2.5
aldolase 2.4
diamine oxidase 2.3
xanthine dehydrogenase 2.3
tissue plasminogen activator 2.3
TPP 2.2
transketolase 2.2
MDP 2.2
TPP 2.1
alpha-mannosidase 2.0
CD10 1.9
papain 1.9
alpha-galactosidase 1.8
ornithine transcarbamylase 1.8
AOR 1.8
urokinase-type plasminogen activator 1.8
gamma-glutamyl transpeptidase 1.8
nitrite reductase 1.7
PAM 1.7
PCP 1.7
nitrite reductase 1.7
TdT 1.7
botulinum neurotoxin 1.7
aspartate aminotransferase 1.6
phytase 1.6
phytase 1.6
AST 1.6
CAD 1.5
CAD 1.5
ADH 1.4
CAD 1.4
CPT 1.4
transcriptase 1.4
APC 1.2
alanine aminotransferase 1.0
renin 1.0
plasmin 1.0
isocitrate dehydrogenase 1.0
thyroid peroxidase 1.0
CPT 0.9
thromboplastin 0.9
isocitrate dehydrogenase 0.8
CPT 0.8
prostate-specific antigen 0.8
CD13 0.8
phosphofructokinase 0.7
glucose-6-phosphate dehydrogenase 0.6
heme oxygenase 0.5
alpha-glucosidase 0.5
MMP 0.5
glutamate dehydrogenase 0.5
glutamate dehydrogenase 0.5
more...
Compound
Coprine 10.3
Iodoquinol 9.1
Cinobufagin 7.6
Chlorozotocin 7.4
Capreomycin 7.4
Cresol 7.3
Carbimazole 7.3
Flunisolide 7.0
Beclomethasone 6.7
Flucloxacillin 6.6
Mesalamine 6.6
Phentermine 6.5
EPB 6.4
Cantril 6.3
Trifluorothymidine 6.1
Prilocaine 6.1
Sanguinarine 6.0
Bicalutamide 5.8
Edrophonium 5.7
Ifosfamide 5.5
Sulfamethoxazole 5.5
MCNU 5.5
Ritodrine 5.5
Pantoprazole 5.5
Chlorpheniramine 5.5
A 71 5.5
Chlorpheniramine 5.4
A 42 5.4
Hydroxychloroquine 5.3
Cyclone 5.2
Diphenhydramine 5.2
Sarin 5.0
Labetalol 5.0
Swainsonine 5.0
ANCA 4.9
Lopinavir 4.9
Daptomycin 4.9
Asbestos 4.9
SVC 4.7
BNP 4.7
Cortisone 4.7
Cabergoline 4.6
Omeprazole 4.6
Nisoldipine 4.6
Terfenadine 4.6
Cidofovir 4.6
Piperacillin 4.6
Cyproterone acetate 4.6
Oxacillin 4.6
Ethylene oxide 4.6
Cefoperazone 4.5
Ethambutol 4.4
Montelukast 4.4
Prednisolone 4.4
Paeoniflorin 4.4
Hydralazine 4.3
Loperamide 4.3
Oxacillin 4.3
Succinylcholine 4.3
Pyrimethamine 4.3
Premarin 4.3
TDI 4.3
Alprazolam 4.3
TEG 4.2
Sulindac 4.2
Cefepime 4.2
His 4.2
BAL 4.2
MME 4.1
Salbutamol 4.1
Sildenafil 4.1
Praziquantel 4.1
CPZ 4.1
2,3-dimercaptosuccinic acid 4.0
Voriconazole 4.0
PCI 4.0
o,p'-DDD 3.9
Terbutaline 3.9
PPF 3.9
Ritonavir 3.9
more...