Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0392680 (
shortness of breath
)
5,217
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hypoglycaemic activity of a petroleum ether extract of the root bark of Salacia oblonga Wall. (Celastraceae) (
SOB
) was studied in streptozotocin (STZ) hyperglycaemic rats. In addition, the anti-lipid peroxidative activity of
SOB
was studied in hyperglycaemic rats. The extract showed significant hypoglycaemia ( p < 0.001), which was supported by an insulin assay. A detailed biochemical study (thiobarbituric acid reactive substances, hydroperoxides, conjugated dienes, glutathione, superoxide dismutase, catalase, glutathione peroxidase, and
glutathione reductase
) in the renal tissue of diabetic animals treated with
SOB
demonstrated promising anti-lipid peroxidative activity. These results suggest that S. oblonga root bark possesses anti-diabetic and anti-peroxidative principles, and may be of value in the treatment of diabetes and associated renal complications.
...
PMID:Anti-peroxidative and hypoglycaemic activity of salacia oblonga extract in diabetic rats. 2121 47
