Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392680 (shortness of breath)
 5,217 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Brain natriuretic peptide (BNP) is a cardiac neurohormone of increasing interest over recent years, with research applications expanding at a rapid rate and new data published on a monthly basis. Initially developed as a diagnostic aid for those with acute shortness of breath, clinical applications are now increasing, and this article reviews these clinical applications of BNP and the evidence for effectiveness of the synthetic BNP analogue nesiritide.
J Renin Angiotensin Aldosterone Syst 2004 Jun
PMID:The utility of BNP in clinical practice. 1529 15

Renin secreting juxtaglomerular cell tumors are extremely rare benign tumors of the kidney. In this case, we highlight the atypical presentation of a young male patient presenting with vague complaints of worsening dyspnea, shortness of breath and anxiety. Initial workup of troponinemia and elevated BNP was initially most suggestive of a major cardiac event. An ejection fraction of 20% confirmed that this patient presented with heart failure. However, only further workup with imaging and renin and aldosterone labs revealed a functional renal mass as the cause. Timely intervention was pursued and pathology of the tumor was consistent with a juxtaglomerular cell tumor.
 ...
PMID:Juxtaglomerular cell tumor in a young male presenting with new onset congestive heart failure. 3229 4