Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392674 (exhaustion)
13,658 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 866
CD8 765
PD-1 441
CD4 429
cytokine 401
insulin 386
ATP 279
Mol 256
IFN 224
PD-L1 217
hemoglobin 153
lymphoid 145
interferon 138
CO2 135
TNF 126
IL-2 113
IL-10 108
Tim-3 107
ANOVA 103
LAG-3 99
CD28 98
CTLA-4 81
IL-6 79
TCR 78
creatine kinase 77
PD1 75
superoxide dismutase 73
ADP 71
mucin 70
TIM-3 69
growth hormone 69
GSH 64
p53 62
glucagon 61
gut 61
T cell receptor 61
thymus 60
lactate dehydrogenase 58
RPE 56
citrate synthase 55
ATPase 54
catalase 53
tumor necrosis factor 53
renin 53
mTOR 52
perforin 51
Mot 48
ACTH 46
beta-endorphin 46
reserved 46
interleukin-6 46
T-bet 45
TIGIT 44
NADH 44
albumin 43
granzyme B 43
IFN-gamma 43
MHC 43
APA 43
prolactin 42
glutathione peroxidase 42
CD57 41
NAD 41
cage 40
endoplasmic reticulum 40
HLA 39
CD19 38
CD27 38
Pol 38
SARS 37
C-reactive protein 37
programmed cell death 1 37
4-1BB 36
fibrinogen 35
Pseudomonas 35
Gen 35
NMR 35
HLA-DR 35
NK1 34
AMP 34
more...
Disease
cancer 962
tumor 794
depersonalization 458
depression 417
HIV 348
stroke 263
diabetes 219
virus infection 197
cold 158
immunodeficiency 133
lymphocytic choriomeningitis 119
AIDS 118
hypertension 110
obesity 104
SEM 103
leukemia 101
tumor growth 95
dehydration 94
melanoma 92
hepatitis C 89
type 2 diabetes 87
anemia 86
ischemia 85
heart failure 85
chronic obstructive pulmonary disease 85
infectious diseases 83
myocardial infarction 73
hypoglycemia 70
hyperglycemia 69
hepatitis B 67
sepsis 67
viremia 65
GSH 64
cardiovascular disease 64
sepsis 63
hepatocellular carcinoma 58
cytomegalovirus 56
tuberculosis 54
Alzheimer's disease 54
tumor progression 54
chronic hepatitis 53
immunopathology 52
lymphoma 51
breast cancer 51
chronic fatigue syndrome 47
influenza 47
asthma 46
coronary heart disease 46
lung cancer 45
dementia 45
cirrhosis 45
cognitive impairment 44
SARS 44
mental illness 44
coronary artery disease 44
psychological distress 44
multiple sclerosis 42
type 1 diabetes 41
metastases 41
atherosclerosis 40
brucellosis 40
malnutrition 39
Mycobacterium 39
chronic lymphocytic leukemia 38
Blocking 38
myocardial ischemia 37
hyperinsulinemia 37
NAME 36
tumorigenesis 35
malaria 34
neuroticism 34
psychological stress 34
aggression 34
suicide 33
carcinoma 33
Duchenne muscular dystrophy 33
acute myeloid leukemia 33
violence 33
multiple myeloma 31
Hodgkin's disease 31
more...
Symptom
exhaustion 13658
fatigue 1281
pain 214
weakness 152
starvation 95
dyspnea 85
discomfort 66
discomfort 61
collapse 57
anesthesia 52
insomnia 50
headache 45
myalgia 42
hypothermia 41
seizures 37
nausea 35
angina 34
sleepiness 33
syncope 32
overweight 31
physical exhaustion 29
anorexia 27
hyperoxia 27
agitation 26
diarrhea 26
dizziness 24
hypercapnia 23
acute stress 22
mental fatigue 20
Ill 19
cough 16
vomiting 16
hopelessness 15
tremor 15
splenomegaly 15
respiratory distress 15
cachexia 15
analgesia 15
hunger 13
asthenia 13
arthralgia 13
stigma 12
chest pain 11
hypocapnia 11
back pain 11
tense 10
apathy 10
acidity 10
menopausal symptoms 9
lethargy 9
muscle cramps 9
low back pain 8
Depressive symptoms 8
colic 8
constipation 8
flushing 8
functional recovery 8
abdominal pain 8
spasticity 8
alexithymia 7
tachypnea 7
twitching 7
hot flushes 7
excessive sweating 6
paresis 6
shortness of breath 6
Muscle soreness 6
abdominal discomfort 6
emaciation 6
memory loss 6
chills 6
Exercise intolerance 5
dystonia 5
despair 5
Wind 5
nausea and vomiting 5
exertional dyspnea 5
catatonia 5
muscle rigidity 5
paresthesia 4
more...
Drug
IL-2 114
caffeine 100
NADH 44
IFN-gamma 40
Dermatol 27
CSF 24
Cardiovasc 24
lactose 21
vitamin E 20
ascorbate 19
lysine 18
Nephron 17
NH3 17
ROS 17
citric acid 15
MAP 13
Monit 12
PDL 11
Spectrum 11
Leaf 10
Glutathione 10
G-CSF 9
FAD 9
Glycerol 9
Salbutamol 8
Glucagon 8
Ethanol 8
Alanine 8
IL-1ra 8
CFS 7
Nephron 7
Diurnal 6
Nitric Oxide 6
ICI 6
nitroglycerin 6
Vitamin E 6
Growth hormone 5
HCH 5
Posture 5
Albumin 5
Dial 5
Captopril 5
Growth hormone 5
CaCl2 5
CaCl2 5
CaCl2 5
Ginseng 4
Check 4
VCR 4
Asthma 4
beta-Galactosidase 4
Histamine 4
Inderal 4
Oxycon 4
Gel 4
Atenolol 4
ACT 3
THF 3
Amiloride 3
Kenyan 3
Ranitidine 3
Ouabain 3
Fructose 3
p75 3
Frontal 3
Bifidobacterium 3
Lactose 3
EPA 3
Galactose 3
niacin 3
PTH 3
Angiotensin II 3
Prednisone 2
CTC 2
ETS 2
Portal 2
IL-11 2
Rituximab 2
Timolol 2
Modafinil 2
more...
Enzyme
creatine kinase 96
superoxide dismutase 95
lactate dehydrogenase 67
ATPase 66
catalase 58
citrate synthase 55
renin 53
ERK 48
glutathione peroxidase 44
mitogen-activated protein kinase 41
granzyme B 40
protein kinase 35
AMP-activated protein kinase 35
focal adhesion kinase 34
alanine aminotransferase 29
aspartate aminotransferase 28
peroxidase 28
phosphofructokinase 26
phosphorylase 25
pyruvate dehydrogenase 24
acetylcholinesterase 22
pyruvate dehydrogenase 20
cytochrome oxidase 20
pyruvate dehydrogenase 20
AMPK 20
glutathione reductase 19
thrombin 19
cholinesterase 18
AMPK 18
alkaline phosphatase 17
PRE 17
proteasome 17
caspase-3 15
ACE 15
succinate dehydrogenase 15
pyruvate kinase 15
hexokinase 15
glucose-6-phosphate dehydrogenase 14
APC 14
protein kinase C 14
beta-galactosidase 13
trypsin 13
calcineurin 12
isocitrate dehydrogenase 12
ACS 12
PARP 12
kallikrein 11
isocitrate dehydrogenase 11
aldehyde dehydrogenase 11
NADPH oxidase 10
reverse transcriptase 10
phosphoenolpyruvate carboxykinase 10
3-hydroxyacyl-CoA dehydrogenase 10
carbonic anhydrase 10
nitrogenase 10
lipase 9
xanthine oxidase 9
RNA polymerase 9
NO synthase 9
malate dehydrogenase 9
CFI 9
lysozyme 9
luciferase 9
phosphoenolpyruvate carboxykinase 9
phosphoenolpyruvate carboxykinase 9
AST 8
MAP 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
NADPH oxidase 8
3-hydroxyacyl-CoA dehydrogenase 8
glutathione S-transferase 8
tryptophan hydroxylase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
PDK1 8
glyceraldehyde-3-phosphate dehydrogenase 8
AMP deaminase 7
phosphatidylinositol 3-kinase 7
ceruloplasmin 7
more...
Compound
oxygen 1884
glucose 968
Dec 907
water 588
Clin 477
DNA 348
ATP 280
CO2 268
calcium 220
phosphate 215
nitrogen 199
sodium 194
TNF 126
ammonia 120
glycerol 115
caffeine 100
iron 99
acetate 98
potassium 97
Cardiol 96
noradrenaline 94
nitrate 86
Lactate 85
phosphocreatine 83
ethanol 80
hydrogen 78
ADP 74
urea 72
ADP 71
ADP 71
GSH 69
GSH 69
nitric oxide 69
arginine 64
galactose 61
glutamine 54
ammonium 54
alanine 53
NAD 52
glutamate 52
salt 52
Insulin 50
phosphorus 48
ACTH 47
sulfate 46
tryptophan 45
NH2 45
NADH 44
Glycogen 44
creatinine 42
carbonate 41
NAD 41
aldosterone 40
tryptophan 40
copper 39
tyrosine 37
tryptophan 37
AMP 37
tryptophan 37
His 35
leucine 35
CoA 32
zinc 31
cyanide 31
methionine 31
cAMP 30
FFA 30
Cortisol 28
MDA 25
Phe 25
Mg2+ 25
nicotinamide 24
acetic acid 23
Adrenal 23
lysine 23
threonine 23
5-HT 23
serine 22
silver 22
manganese 22
more...