Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0392674 (
exhaustion
)
13,658
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
866
CD8
765
PD-1
441
CD4
429
cytokine
401
insulin
386
ATP
279
Mol
256
IFN
224
PD-L1
217
hemoglobin
153
lymphoid
145
interferon
138
CO2
135
TNF
126
IL-2
113
IL-10
108
Tim-3
107
ANOVA
103
LAG-3
99
CD28
98
CTLA-4
81
IL-6
79
TCR
78
creatine kinase
77
PD1
75
superoxide dismutase
73
ADP
71
mucin
70
TIM-3
69
growth hormone
69
GSH
64
p53
62
glucagon
61
gut
61
T cell receptor
61
thymus
60
lactate dehydrogenase
58
RPE
56
citrate synthase
55
ATPase
54
catalase
53
tumor necrosis factor
53
renin
53
mTOR
52
perforin
51
Mot
48
ACTH
46
beta-endorphin
46
reserved
46
interleukin-6
46
T-bet
45
TIGIT
44
NADH
44
albumin
43
granzyme B
43
IFN-gamma
43
MHC
43
APA
43
prolactin
42
glutathione peroxidase
42
CD57
41
NAD
41
cage
40
endoplasmic reticulum
40
HLA
39
CD19
38
CD27
38
Pol
38
SARS
37
C-reactive protein
37
programmed cell death 1
37
4-1BB
36
fibrinogen
35
Pseudomonas
35
Gen
35
NMR
35
HLA-DR
35
NK1
34
AMP
34
more...
Disease
cancer
962
tumor
794
depersonalization
458
depression
417
HIV
348
stroke
263
diabetes
219
virus infection
197
cold
158
immunodeficiency
133
lymphocytic choriomeningitis
119
AIDS
118
hypertension
110
obesity
104
SEM
103
leukemia
101
tumor growth
95
dehydration
94
melanoma
92
hepatitis C
89
type 2 diabetes
87
anemia
86
ischemia
85
heart failure
85
chronic obstructive pulmonary disease
85
infectious diseases
83
myocardial infarction
73
hypoglycemia
70
hyperglycemia
69
hepatitis B
67
sepsis
67
viremia
65
GSH
64
cardiovascular disease
64
sepsis
63
hepatocellular carcinoma
58
cytomegalovirus
56
tuberculosis
54
Alzheimer's disease
54
tumor progression
54
chronic hepatitis
53
immunopathology
52
lymphoma
51
breast cancer
51
chronic fatigue syndrome
47
influenza
47
asthma
46
coronary heart disease
46
lung cancer
45
dementia
45
cirrhosis
45
cognitive impairment
44
SARS
44
mental illness
44
coronary artery disease
44
psychological distress
44
multiple sclerosis
42
type 1 diabetes
41
metastases
41
atherosclerosis
40
brucellosis
40
malnutrition
39
Mycobacterium
39
chronic lymphocytic leukemia
38
Blocking
38
myocardial ischemia
37
hyperinsulinemia
37
NAME
36
tumorigenesis
35
malaria
34
neuroticism
34
psychological stress
34
aggression
34
suicide
33
carcinoma
33
Duchenne muscular dystrophy
33
acute myeloid leukemia
33
violence
33
multiple myeloma
31
Hodgkin's disease
31
more...
Symptom
exhaustion
13658
fatigue
1281
pain
214
weakness
152
starvation
95
dyspnea
85
discomfort
66
discomfort
61
collapse
57
anesthesia
52
insomnia
50
headache
45
myalgia
42
hypothermia
41
seizures
37
nausea
35
angina
34
sleepiness
33
syncope
32
overweight
31
physical exhaustion
29
anorexia
27
hyperoxia
27
agitation
26
diarrhea
26
dizziness
24
hypercapnia
23
acute stress
22
mental fatigue
20
Ill
19
cough
16
vomiting
16
hopelessness
15
tremor
15
splenomegaly
15
respiratory distress
15
cachexia
15
analgesia
15
hunger
13
asthenia
13
arthralgia
13
stigma
12
chest pain
11
hypocapnia
11
back pain
11
tense
10
apathy
10
acidity
10
menopausal symptoms
9
lethargy
9
muscle cramps
9
low back pain
8
Depressive symptoms
8
colic
8
constipation
8
flushing
8
functional recovery
8
abdominal pain
8
spasticity
8
alexithymia
7
tachypnea
7
twitching
7
hot flushes
7
excessive sweating
6
paresis
6
shortness of breath
6
Muscle soreness
6
abdominal discomfort
6
emaciation
6
memory loss
6
chills
6
Exercise intolerance
5
dystonia
5
despair
5
Wind
5
nausea and vomiting
5
exertional dyspnea
5
catatonia
5
muscle rigidity
5
paresthesia
4
more...
Drug
IL-2
114
caffeine
100
NADH
44
IFN-gamma
40
Dermatol
27
CSF
24
Cardiovasc
24
lactose
21
vitamin E
20
ascorbate
19
lysine
18
Nephron
17
NH3
17
ROS
17
citric acid
15
MAP
13
Monit
12
PDL
11
Spectrum
11
Leaf
10
Glutathione
10
G-CSF
9
FAD
9
Glycerol
9
Salbutamol
8
Glucagon
8
Ethanol
8
Alanine
8
IL-1ra
8
CFS
7
Nephron
7
Diurnal
6
Nitric Oxide
6
ICI
6
nitroglycerin
6
Vitamin E
6
Growth hormone
5
HCH
5
Posture
5
Albumin
5
Dial
5
Captopril
5
Growth hormone
5
CaCl2
5
CaCl2
5
CaCl2
5
Ginseng
4
Check
4
VCR
4
Asthma
4
beta-Galactosidase
4
Histamine
4
Inderal
4
Oxycon
4
Gel
4
Atenolol
4
ACT
3
THF
3
Amiloride
3
Kenyan
3
Ranitidine
3
Ouabain
3
Fructose
3
p75
3
Frontal
3
Bifidobacterium
3
Lactose
3
EPA
3
Galactose
3
niacin
3
PTH
3
Angiotensin II
3
Prednisone
2
CTC
2
ETS
2
Portal
2
IL-11
2
Rituximab
2
Timolol
2
Modafinil
2
more...
Enzyme
creatine kinase
96
superoxide dismutase
95
lactate dehydrogenase
67
ATPase
66
catalase
58
citrate synthase
55
renin
53
ERK
48
glutathione peroxidase
44
mitogen-activated protein kinase
41
granzyme B
40
protein kinase
35
AMP-activated protein kinase
35
focal adhesion kinase
34
alanine aminotransferase
29
aspartate aminotransferase
28
peroxidase
28
phosphofructokinase
26
phosphorylase
25
pyruvate dehydrogenase
24
acetylcholinesterase
22
pyruvate dehydrogenase
20
cytochrome oxidase
20
pyruvate dehydrogenase
20
AMPK
20
glutathione reductase
19
thrombin
19
cholinesterase
18
AMPK
18
alkaline phosphatase
17
PRE
17
proteasome
17
caspase-3
15
ACE
15
succinate dehydrogenase
15
pyruvate kinase
15
hexokinase
15
glucose-6-phosphate dehydrogenase
14
APC
14
protein kinase C
14
beta-galactosidase
13
trypsin
13
calcineurin
12
isocitrate dehydrogenase
12
ACS
12
PARP
12
kallikrein
11
isocitrate dehydrogenase
11
aldehyde dehydrogenase
11
NADPH oxidase
10
reverse transcriptase
10
phosphoenolpyruvate carboxykinase
10
3-hydroxyacyl-CoA dehydrogenase
10
carbonic anhydrase
10
nitrogenase
10
lipase
9
xanthine oxidase
9
RNA polymerase
9
NO synthase
9
malate dehydrogenase
9
CFI
9
lysozyme
9
luciferase
9
phosphoenolpyruvate carboxykinase
9
phosphoenolpyruvate carboxykinase
9
AST
8
MAP
8
aldehyde dehydrogenase
8
aldehyde dehydrogenase
8
NADPH oxidase
8
3-hydroxyacyl-CoA dehydrogenase
8
glutathione S-transferase
8
tryptophan hydroxylase
8
aldehyde dehydrogenase
8
aldehyde dehydrogenase
8
PDK1
8
glyceraldehyde-3-phosphate dehydrogenase
8
AMP deaminase
7
phosphatidylinositol 3-kinase
7
ceruloplasmin
7
more...
Compound
oxygen
1884
glucose
968
Dec
907
water
588
Clin
477
DNA
348
ATP
280
CO2
268
calcium
220
phosphate
215
nitrogen
199
sodium
194
TNF
126
ammonia
120
glycerol
115
caffeine
100
iron
99
acetate
98
potassium
97
Cardiol
96
noradrenaline
94
nitrate
86
Lactate
85
phosphocreatine
83
ethanol
80
hydrogen
78
ADP
74
urea
72
ADP
71
ADP
71
GSH
69
GSH
69
nitric oxide
69
arginine
64
galactose
61
glutamine
54
ammonium
54
alanine
53
NAD
52
glutamate
52
salt
52
Insulin
50
phosphorus
48
ACTH
47
sulfate
46
tryptophan
45
NH2
45
NADH
44
Glycogen
44
creatinine
42
carbonate
41
NAD
41
aldosterone
40
tryptophan
40
copper
39
tyrosine
37
tryptophan
37
AMP
37
tryptophan
37
His
35
leucine
35
CoA
32
zinc
31
cyanide
31
methionine
31
cAMP
30
FFA
30
Cortisol
28
MDA
25
Phe
25
Mg2+
25
nicotinamide
24
acetic acid
23
Adrenal
23
lysine
23
threonine
23
5-HT
23
serine
22
silver
22
manganese
22
more...