Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0392525 (
nephrolithiasis
)
2,669
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
160
parathyroid hormone
129
PTH
65
proximal tubule
50
insulin
42
chronic renal failure
38
CLCN5
36
X-linked
36
Mol
36
osteopontin
36
She
35
chloride channel
28
AMP
26
alkaline phosphatase
25
X-linked recessive
24
Pol
24
calcium-sensing receptor
23
ClC-5
23
collecting duct
22
SLC3A1
20
vitamin D receptor
20
albumin
20
gut
20
ATPase
18
CLC-5
17
SLC7A9
17
hypoxanthine-guanine phosphoribosyltransferase
17
GFR
17
lactate dehydrogenase
15
parathormone
15
CYP24A1
15
carbonic anhydrase
15
protease inhibitor
13
superoxide dismutase
12
renin
11
brush border
11
CLC
11
MRI
11
RTA
10
AGXT
10
SLC34A1
10
xanthine oxidase
9
SLC22A12
9
RST
9
C-reactive protein
9
SLC2A9
9
hemoglobin
9
osteocalcin
9
tap
8
megalin
8
SLC26A6
8
PH1
8
growth hormone
8
collagen
8
Claudin-16
8
reserved
8
SLC34A3
8
calcitonin
8
bikunin
8
OPN
7
CaSR
7
NKCC2
7
glycoprotein
7
ATP6V1B1
7
ROMK
7
catalase
7
TOF
7
alanine-glyoxylate aminotransferase
7
claudin-14
7
ClC-2
7
OCRL1
7
GLUT9
7
prothrombin
7
rBAT
6
OCRL
6
glucose transporter
6
FGF23
6
xanthine dehydrogenase
6
Mil
6
AE1
6
more...
Disease
nephrolithiasis
2669
hypercalciuria
409
nephrocalcinosis
268
urolithiasis
212
primary hyperparathyroidism
194
hypercalcemia
174
hypertension
158
hyperoxaluria
144
renal disease
143
renal failure
143
pyelonephritis
123
diabetes
116
hyperparathyroidism
106
obesity
105
proteinuria
99
renal tubular acidosis
98
cancer
83
osteoporosis
80
urinary tract infection
72
chronic renal failure
68
cystinuria
68
tumor
66
primary hyperoxaluria
65
gout
64
adenoma
63
hyperuricemia
61
hydronephrosis
60
metabolic syndrome
56
ureter
54
renal insufficiency
52
bone disease
49
acute renal failure
46
Dent's disease
45
rickets
44
carcinoma
42
cardiovascular disease
38
interstitial nephritis
34
sarcoidosis
32
sponge kidney
32
glomerulonephritis
30
HIV
29
type 2 diabetes
28
polycystic kidney
27
uropathy
26
nephritis
25
Fanconi syndrome
24
Fanconi
24
osteomalacia
24
arthritis
24
gallstones
23
renal cell carcinoma
23
malabsorption
23
sepsis
22
glomerulopathy
22
genetic disorder
22
renal impairment
22
sepsis
21
plaque
21
inflammatory bowel disease
21
dehydration
20
wasting
20
Idiopathic hypercalciuria
20
renal cancer
20
oxalosis
20
multiple endocrine neoplasia
19
atherosclerosis
19
Bartter's syndrome
19
hypoparathyroidism
19
tuberculosis
18
pancreatitis
18
metabolic disorder
18
immunodeficiency
18
Crohn's disease
17
depression
17
tophi
16
Lesch-Nyhan syndrome
16
Lowe syndrome
16
cirrhosis
16
vitamin D deficiency
15
AIDS
15
more...
Symptom
pain
71
renal colic
58
flank pain
51
abdominal pain
48
diarrhea
36
weakness
25
polyuria
25
overweight
22
fatigue
21
seizures
20
vomiting
17
bone pain
12
dysuria
11
colic
11
nausea
10
anesthesia
10
polydipsia
9
hypotonia
9
sleepiness
8
back pain
8
ataxia
7
constipation
6
angina
6
oliguria
6
paresthesia
6
discomfort
6
acidity
6
dizziness
6
discomfort
6
analgesia
6
hepatomegaly
5
headache
5
loin pain
5
dyspnea
4
anorexia
4
asthenia
4
lethargy
4
acute abdominal pain
4
livedo
4
hypothermia
4
chronic constipation
3
paresis
3
Ill
3
pelvic pain
3
low back pain
3
nausea and vomiting
3
renal pain
3
myalgia
3
decreased appetite
3
hyperemesis gravidarum
3
splenomegaly
2
shortness of breath
2
hyperemesis
2
tremor
2
tonic-clonic seizure
2
abdominal discomfort
2
urinary frequency
2
right lower quadrant pain
2
acute pain
2
chills
2
collapse
2
groin pain
2
spasticity
2
Decreased activity
1
cyanosis
1
swollen scrotum
1
night sweats
1
bladder pain
1
stridor
1
dystonia
1
syncope
1
nocturnal polyuria
1
Urge incontinence
1
Acute urinary retention
1
emaciation
1
dental pain
1
enuresis
1
ophthalmoplegia
1
arthralgia
1
productive cough
1
more...
Drug
PTH
65
Nephron
26
Nephron
26
Potassium citrate
22
Dial
17
Indinavir
12
ascorbate
9
lysine
8
Dermatol
8
ROC
6
citric acid
6
Cinacalcet
5
Monit
5
lactose
4
Zonisamide
4
Cardiovasc
4
ROS
4
Tenofovir
4
Indomethacin
4
PMPA
4
vitamin E
4
DMSA
3
caffeine
3
CTX
3
NAG
3
Hydrochlorothiazide
3
Rasburicase
3
Topamax
2
Growth hormone
2
ampicillin
2
Gabapentin
2
Leaf
2
Rasburicase
2
Coral
2
Fragment
2
Growth hormone
2
Fluconazole
2
Zonegran
2
Tiopronin
2
Crixivan
2
Benazepril hydrochloride
1
Nitisinone
1
Dyazide
1
Plavix
1
Isradipine
1
Infliximab
1
Rimonabant
1
ADR
1
Infliximab
1
Meropenem
1
Rosiglitazone
1
Oseltamivir
1
Rituximab
1
CTX
1
CTT
1
Spectrum
1
Coumadin
1
THF
1
Angiotensin II
1
Glycyrrhiza
1
Vitamin B
1
Denosumab
1
CaCl2
1
NVP
1
Gel
1
Teriparatide
1
CTA
1
NH3
1
Carboxyatractyloside
1
Beta-2
1
Indapamide
1
Albumin
1
pyridoxal phosphate
1
Metolazone
1
Felbatol
1
Amiloride
1
CTC
1
Estrogens
1
Lotrel
1
Colombo
1
more...
Enzyme
alkaline phosphatase
25
ATPase
18
lactate dehydrogenase
17
superoxide dismutase
15
carbonic anhydrase
15
urease
14
urease
14
hypoxanthine-guanine phosphoribosyltransferase
11
renin
11
catalase
11
xanthine oxidase
10
AGT
9
adenine phosphoribosyltransferase
8
xanthine dehydrogenase
7
gamma-glutamyl transpeptidase
6
reverse transcriptase
6
peroxidase
5
NADPH oxidase
5
ACE
5
NADPH oxidase
5
uricase
5
calcineurin
4
glutathione peroxidase
4
glyoxylate reductase
4
glyoxylate reductase
4
HK2
3
mitogen-activated protein kinase
3
luciferase
3
creatine kinase
3
focal adhesion kinase
3
thromboplastin
2
homogentisate 1,2-dioxygenase
2
glycolate oxidase
2
pyruvate dehydrogenase
2
PNL
2
thrombin
2
caspase-3
2
hydroxypyruvate reductase
2
pyruvate dehydrogenase
2
caspase-9
2
ERK
2
endonuclease
2
protein kinase
2
hydroxypyruvate reductase
2
lysozyme
2
hexosaminidase
2
pyruvate dehydrogenase
2
protein kinase C
2
acid phosphatase
1
PAT
1
DCF
1
nucleotide pyrophosphatase
1
hyaluronidase
1
cystathionine beta-synthase
1
leucine aminopeptidase
1
alanine aminopeptidase
1
ceruloplasmin
1
RNase
1
FAST
1
alpha-glucosidase
1
phospholipase A2
1
glutathione reductase
1
CD13
1
oxalate oxidase
1
RNase
1
hyaluronidase
1
urokinase-type plasminogen activator
1
oxalate decarboxylase
1
alanine aminotransferase
1
AMP-activated protein kinase
1
PRPP synthetase
1
cathepsin K
1
oligopeptidase B
1
paraoxonase
1
lactic acid dehydrogenase
1
4-hydroxyphenylpyruvate dioxygenase
1
glucose-6-phosphatase
1
1-hydroxylase
1
citrate lyase
1
adenylate cyclase
1
more...
Compound
calcium
1013
oxalate
557
phosphate
254
Clin
251
Dec
180
sodium
179
creatinine
157
potassium
145
water
114
vitamin D
95
ammonium
65
PEG
55
PEG
52
salt
49
phosphorus
49
oxalic acid
42
carbonate
39
DNA
36
sulfate
35
His
34
urea
32
glucose
29
Uric acid
28
CIT
23
hydrogen
22
oxygen
19
nitrogen
18
Dial
17
arginine
17
Vitamin D
16
cAMP
16
sodium chloride
14
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
ammonia
13
oxalic acid
13
aldosterone
13
oxalic acid
13
oxalic acid
13
Topiramate
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
oxalic acid
13
HPP
12
AMP
12
Indinavir
12
lysine
11
galactose
10
Mg2+
9
Thiazide
8
proline
8
hydroxide
7
Melamine
7
25-dihydroxycholecalciferol
7
TOF
7
ornithine
7
Cystine
7
ornithine
7
ornithine
7
DHA
7
ornithine
7
zinc
7
ornithine
7
DHA
6
DHA
6
Cystine
6
8-OHdG
6
nitric oxide
6
HCO
6
MDA
6
bromide
5
TNF
5
more...