Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392525 (nephrolithiasis)
2,669 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 160
parathyroid hormone 129
PTH 65
proximal tubule 50
insulin 42
chronic renal failure 38
CLCN5 36
X-linked 36
Mol 36
osteopontin 36
She 35
chloride channel 28
AMP 26
alkaline phosphatase 25
X-linked recessive 24
Pol 24
calcium-sensing receptor 23
ClC-5 23
collecting duct 22
SLC3A1 20
vitamin D receptor 20
albumin 20
gut 20
ATPase 18
CLC-5 17
SLC7A9 17
hypoxanthine-guanine phosphoribosyltransferase 17
GFR 17
lactate dehydrogenase 15
parathormone 15
CYP24A1 15
carbonic anhydrase 15
protease inhibitor 13
superoxide dismutase 12
renin 11
brush border 11
CLC 11
MRI 11
RTA 10
AGXT 10
SLC34A1 10
xanthine oxidase 9
SLC22A12 9
RST 9
C-reactive protein 9
SLC2A9 9
hemoglobin 9
osteocalcin 9
tap 8
megalin 8
SLC26A6 8
PH1 8
growth hormone 8
collagen 8
Claudin-16 8
reserved 8
SLC34A3 8
calcitonin 8
bikunin 8
OPN 7
CaSR 7
NKCC2 7
glycoprotein 7
ATP6V1B1 7
ROMK 7
catalase 7
TOF 7
alanine-glyoxylate aminotransferase 7
claudin-14 7
ClC-2 7
OCRL1 7
GLUT9 7
prothrombin 7
rBAT 6
OCRL 6
glucose transporter 6
FGF23 6
xanthine dehydrogenase 6
Mil 6
AE1 6
more...
Disease
nephrolithiasis 2669
hypercalciuria 409
nephrocalcinosis 268
urolithiasis 212
primary hyperparathyroidism 194
hypercalcemia 174
hypertension 158
hyperoxaluria 144
renal disease 143
renal failure 143
pyelonephritis 123
diabetes 116
hyperparathyroidism 106
obesity 105
proteinuria 99
renal tubular acidosis 98
cancer 83
osteoporosis 80
urinary tract infection 72
chronic renal failure 68
cystinuria 68
tumor 66
primary hyperoxaluria 65
gout 64
adenoma 63
hyperuricemia 61
hydronephrosis 60
metabolic syndrome 56
ureter 54
renal insufficiency 52
bone disease 49
acute renal failure 46
Dent's disease 45
rickets 44
carcinoma 42
cardiovascular disease 38
interstitial nephritis 34
sarcoidosis 32
sponge kidney 32
glomerulonephritis 30
HIV 29
type 2 diabetes 28
polycystic kidney 27
uropathy 26
nephritis 25
Fanconi syndrome 24
Fanconi 24
osteomalacia 24
arthritis 24
gallstones 23
renal cell carcinoma 23
malabsorption 23
sepsis 22
glomerulopathy 22
genetic disorder 22
renal impairment 22
sepsis 21
plaque 21
inflammatory bowel disease 21
dehydration 20
wasting 20
Idiopathic hypercalciuria 20
renal cancer 20
oxalosis 20
multiple endocrine neoplasia 19
atherosclerosis 19
Bartter's syndrome 19
hypoparathyroidism 19
tuberculosis 18
pancreatitis 18
metabolic disorder 18
immunodeficiency 18
Crohn's disease 17
depression 17
tophi 16
Lesch-Nyhan syndrome 16
Lowe syndrome 16
cirrhosis 16
vitamin D deficiency 15
AIDS 15
more...
Symptom
pain 71
renal colic 58
flank pain 51
abdominal pain 48
diarrhea 36
weakness 25
polyuria 25
overweight 22
fatigue 21
seizures 20
vomiting 17
bone pain 12
dysuria 11
colic 11
nausea 10
anesthesia 10
polydipsia 9
hypotonia 9
sleepiness 8
back pain 8
ataxia 7
constipation 6
angina 6
oliguria 6
paresthesia 6
discomfort 6
acidity 6
dizziness 6
discomfort 6
analgesia 6
hepatomegaly 5
headache 5
loin pain 5
dyspnea 4
anorexia 4
asthenia 4
lethargy 4
acute abdominal pain 4
livedo 4
hypothermia 4
chronic constipation 3
paresis 3
Ill 3
pelvic pain 3
low back pain 3
nausea and vomiting 3
renal pain 3
myalgia 3
decreased appetite 3
hyperemesis gravidarum 3
splenomegaly 2
shortness of breath 2
hyperemesis 2
tremor 2
tonic-clonic seizure 2
abdominal discomfort 2
urinary frequency 2
right lower quadrant pain 2
acute pain 2
chills 2
collapse 2
groin pain 2
spasticity 2
Decreased activity 1
cyanosis 1
swollen scrotum 1
night sweats 1
bladder pain 1
stridor 1
dystonia 1
syncope 1
nocturnal polyuria 1
Urge incontinence 1
Acute urinary retention 1
emaciation 1
dental pain 1
enuresis 1
ophthalmoplegia 1
arthralgia 1
productive cough 1
more...
Drug
PTH 65
Nephron 26
Nephron 26
Potassium citrate 22
Dial 17
Indinavir 12
ascorbate 9
lysine 8
Dermatol 8
ROC 6
citric acid 6
Cinacalcet 5
Monit 5
lactose 4
Zonisamide 4
Cardiovasc 4
ROS 4
Tenofovir 4
Indomethacin 4
PMPA 4
vitamin E 4
DMSA 3
caffeine 3
CTX 3
NAG 3
Hydrochlorothiazide 3
Rasburicase 3
Topamax 2
Growth hormone 2
ampicillin 2
Gabapentin 2
Leaf 2
Rasburicase 2
Coral 2
Fragment 2
Growth hormone 2
Fluconazole 2
Zonegran 2
Tiopronin 2
Crixivan 2
Benazepril hydrochloride 1
Nitisinone 1
Dyazide 1
Plavix 1
Isradipine 1
Infliximab 1
Rimonabant 1
ADR 1
Infliximab 1
Meropenem 1
Rosiglitazone 1
Oseltamivir 1
Rituximab 1
CTX 1
CTT 1
Spectrum 1
Coumadin 1
THF 1
Angiotensin II 1
Glycyrrhiza 1
Vitamin B 1
Denosumab 1
CaCl2 1
NVP 1
Gel 1
Teriparatide 1
CTA 1
NH3 1
Carboxyatractyloside 1
Beta-2 1
Indapamide 1
Albumin 1
pyridoxal phosphate 1
Metolazone 1
Felbatol 1
Amiloride 1
CTC 1
Estrogens 1
Lotrel 1
Colombo 1
more...
Enzyme
alkaline phosphatase 25
ATPase 18
lactate dehydrogenase 17
superoxide dismutase 15
carbonic anhydrase 15
urease 14
urease 14
hypoxanthine-guanine phosphoribosyltransferase 11
renin 11
catalase 11
xanthine oxidase 10
AGT 9
adenine phosphoribosyltransferase 8
xanthine dehydrogenase 7
gamma-glutamyl transpeptidase 6
reverse transcriptase 6
peroxidase 5
NADPH oxidase 5
ACE 5
NADPH oxidase 5
uricase 5
calcineurin 4
glutathione peroxidase 4
glyoxylate reductase 4
glyoxylate reductase 4
HK2 3
mitogen-activated protein kinase 3
luciferase 3
creatine kinase 3
focal adhesion kinase 3
thromboplastin 2
homogentisate 1,2-dioxygenase 2
glycolate oxidase 2
pyruvate dehydrogenase 2
PNL 2
thrombin 2
caspase-3 2
hydroxypyruvate reductase 2
pyruvate dehydrogenase 2
caspase-9 2
ERK 2
endonuclease 2
protein kinase 2
hydroxypyruvate reductase 2
lysozyme 2
hexosaminidase 2
pyruvate dehydrogenase 2
protein kinase C 2
acid phosphatase 1
PAT 1
DCF 1
nucleotide pyrophosphatase 1
hyaluronidase 1
cystathionine beta-synthase 1
leucine aminopeptidase 1
alanine aminopeptidase 1
ceruloplasmin 1
RNase 1
FAST 1
alpha-glucosidase 1
phospholipase A2 1
glutathione reductase 1
CD13 1
oxalate oxidase 1
RNase 1
hyaluronidase 1
urokinase-type plasminogen activator 1
oxalate decarboxylase 1
alanine aminotransferase 1
AMP-activated protein kinase 1
PRPP synthetase 1
cathepsin K 1
oligopeptidase B 1
paraoxonase 1
lactic acid dehydrogenase 1
4-hydroxyphenylpyruvate dioxygenase 1
glucose-6-phosphatase 1
1-hydroxylase 1
citrate lyase 1
adenylate cyclase 1
more...
Compound
calcium 1013
oxalate 557
phosphate 254
Clin 251
Dec 180
sodium 179
creatinine 157
potassium 145
water 114
vitamin D 95
ammonium 65
PEG 55
PEG 52
salt 49
phosphorus 49
oxalic acid 42
carbonate 39
DNA 36
sulfate 35
His 34
urea 32
glucose 29
Uric acid 28
CIT 23
hydrogen 22
oxygen 19
nitrogen 18
Dial 17
arginine 17
Vitamin D 16
cAMP 16
sodium chloride 14
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
ammonia 13
oxalic acid 13
aldosterone 13
oxalic acid 13
oxalic acid 13
Topiramate 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
HPP 12
AMP 12
Indinavir 12
lysine 11
galactose 10
Mg2+ 9
Thiazide 8
proline 8
hydroxide 7
Melamine 7
25-dihydroxycholecalciferol 7
TOF 7
ornithine 7
Cystine 7
ornithine 7
ornithine 7
DHA 7
ornithine 7
zinc 7
ornithine 7
DHA 6
DHA 6
Cystine 6
8-OHdG 6
nitric oxide 6
HCO 6
MDA 6
bromide 5
TNF 5
more...