Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392525 (nephrolithiasis)
 2,669 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 160
parathyroid hormone 129
PTH 65
proximal tubule 50
insulin 42
chronic renal failure 38
osteopontin 36
Mol 36
CLCN5 36
X-linked 36
She 35
chloride channel 28
AMP 26
alkaline phosphatase 25
X-linked recessive 24
Pol 24
calcium-sensing receptor 23
ClC-5 23
collecting duct 22
vitamin D receptor 20
albumin 20
gut 20
SLC3A1 20
ATPase 18
SLC7A9 17
CLC-5 17
hypoxanthine-guanine phosphoribosyltransferase 17
GFR 17
carbonic anhydrase 15
lactate dehydrogenase 15
parathormone 15
CYP24A1 15
protease inhibitor 13
superoxide dismutase 12
MRI 11
CLC 11
renin 11
brush border 11
SLC34A1 10
RTA 10
AGXT 10
SLC22A12 9
C-reactive protein 9
SLC2A9 9
osteocalcin 9
RST 9
xanthine oxidase 9
hemoglobin 9
growth hormone 8
SLC26A6 8
SLC34A3 8
bikunin 8
calcitonin 8
megalin 8
tap 8
Claudin-16 8
reserved 8
collagen 8
PH1 8
NKCC2 7
OCRL1 7
ATP6V1B1 7
glycoprotein 7
TOF 7
catalase 7
ClC-2 7
GLUT9 7
alanine-glyoxylate aminotransferase 7
claudin-14 7
OPN 7
CaSR 7
ROMK 7
prothrombin 7
Mil 6
tumor necrosis factor 6
OCRL 6
IgA 6
glucose transporter 6
fused 6
Tamm-Horsfall glycoprotein 6
rBAT 6
FGF23 6
xanthine dehydrogenase 6
GRHPR 6
AE1 6
cubilin 6
San 5
hydroxypyruvate reductase 5
GSH 5
gastrin 5
uropontin 5
TRPV5 5
uromodulin 5
CD44 5
vasopressin 5
anion exchanger 5
HPT 5
cytokine 5
TNF 5
calcium sensing receptor 5
UTR 5
PH2 5
NHERF1 5
glutathione peroxidase 4
interleukin-6 4
peroxidase 4
Parathyroid hormone 4
CYP27B1 4
SMA 4
IL-6 4
glucagon 4
SLC4A1 4
barttin 4
NHE3 4
G protein-coupled receptor 4
BSC-1 4
monocyte chemoattractant protein-1 4
CAT 4
NCCT 4
phosphatase 4
ATP6V0A4 4
calcineurin 4
JAMA 4
E-cadherin 4
HSPG 4
ROS 4
solute carrier 4
Men 4
MCP-1 4
SLC34A2 4
HPRT 4
lectin 4
claudin 16 4
heparan sulfate proteoglycan 4
LC3 3
p38 3
Wilson disease 3
Pseudomonas 3
novel gene 3
LDH 3
ATP 3
HM3 3
non-functional 3
THP 3
transferrin 3
urate transporter 1 3
SAT-1 3
Bcl-2 3
p65 3
THC 3
matrix protein 3
NAG 3
inter-alpha-trypsin inhibitor 3
renal amyloidosis 3
PPAR 3
LDL receptor 3
SLC13A2 3
chloride channel 7 3
UTI 3
p53 3
more...
Disease
nephrolithiasis 2669
hypercalciuria 409
nephrocalcinosis 268
urolithiasis 212
primary hyperparathyroidism 194
hypercalcemia 174
hypertension 158
hyperoxaluria 144
renal disease 143
renal failure 143
pyelonephritis 123
diabetes 116
hyperparathyroidism 106
obesity 105
proteinuria 99
renal tubular acidosis 98
cancer 83
osteoporosis 80
urinary tract infection 72
cystinuria 68
chronic renal failure 68
tumor 66
primary hyperoxaluria 65
gout 64
adenoma 63
hyperuricemia 61
hydronephrosis 60
metabolic syndrome 56
ureter 54
renal insufficiency 52
bone disease 49
acute renal failure 46
Dent's disease 45
rickets 44
carcinoma 42
cardiovascular disease 38
interstitial nephritis 34
sponge kidney 32
sarcoidosis 32
glomerulonephritis 30
HIV 29
type 2 diabetes 28
polycystic kidney 27
uropathy 26
nephritis 25
Fanconi 24
Fanconi syndrome 24
osteomalacia 24
arthritis 24
malabsorption 23
gallstones 23
renal cell carcinoma 23
renal impairment 22
sepsis 22
genetic disorder 22
glomerulopathy 22
sepsis 21
inflammatory bowel disease 21
plaque 21
wasting 20
oxalosis 20
renal cancer 20
dehydration 20
Idiopathic hypercalciuria 20
Bartter's syndrome 19
atherosclerosis 19
hypoparathyroidism 19
multiple endocrine neoplasia 19
pancreatitis 18
immunodeficiency 18
tuberculosis 18
metabolic disorder 18
Crohn's disease 17
depression 17
Lesch-Nyhan syndrome 16
Lowe syndrome 16
tophi 16
cirrhosis 16
vitamin D deficiency 15
squamous cell carcinoma 15
AIDS 15
stroke 15
peptic ulcer 14
epilepsy 14
uremia 14
amyloidosis 13
urinary tract obstruction 13
aminoaciduria 13
liver disease 13
ischemia 13
SEM 13
Distal renal tubular acidosis 12
failure to thrive 12
bacteriuria 12
anemia 12
osteitis 12
glomerulosclerosis 12
ureterolithiasis 12
ulcerative colitis 12
APRT deficiency 12
recurrent urinary tract infection 11
dyslipidemia 11
Parathyroid 11
Xanthogranulomatous pyelonephritis 11
pyonephrosis 11
Autosomal dominant polycystic kidney disease 11
myocardial infarction 11
renal cyst 11
staghorn calculus 11
cystic fibrosis 10
azotemia 10
IgA nephropathy 10
diabetic nephropathy 10
incontinence 10
Parathyroid carcinoma 10
nephrotic syndrome 10
chronic renal insufficiency 10
calcinosis 10
dysplasia 9
cystitis 9
rare disease 9
deafness 9
prostate cancer 9
PDB 9
infectious diseases 9
adenocarcinoma 9
endocrine disorder 9
rheumatoid arthritis 9
appendicitis 9
hypothyroidism 8
metastases 8
glucose intolerance 8
colitis 8
urethra 8
bowel obstruction 8
preeclampsia 8
parathyroid hyperplasia 8
peritonitis 8
heart failure 8
neurogenic bladder 7
uricosuria 7
mental retardation 7
urosepsis 7
West 7
pyuria 7
coronary artery disease 7
coronary heart disease 7
pneumonia 7
incontinence 7
metabolic alkalosis 7
ventricular hypertrophy 7
mental retardation 7
tetany 7
prostatitis 7
Proteus 7
rash 7
chronic glomerulonephritis 6
malnutrition 6
steatorrhea 6
glycogen storage disease 6
more...
Symptom
pain 71
renal colic 58
flank pain 51
abdominal pain 48
diarrhea 36
polyuria 25
weakness 25
overweight 22
fatigue 21
seizures 20
vomiting 17
bone pain 12
colic 11
dysuria 11
nausea 10
anesthesia 10
polydipsia 9
hypotonia 9
back pain 8
sleepiness 8
ataxia 7
constipation 6
acidity 6
angina 6
oliguria 6
paresthesia 6
dizziness 6
analgesia 6
discomfort 6
discomfort 6
loin pain 5
headache 5
hepatomegaly 5
dyspnea 4
anorexia 4
asthenia 4
acute abdominal pain 4
hypothermia 4
lethargy 4
livedo 4
chronic constipation 3
paresis 3
Ill 3
pelvic pain 3
nausea and vomiting 3
hyperemesis gravidarum 3
decreased appetite 3
renal pain 3
myalgia 3
low back pain 3
splenomegaly 2
shortness of breath 2
hyperemesis 2
tremor 2
tonic-clonic seizure 2
collapse 2
urinary frequency 2
right lower quadrant pain 2
acute pain 2
chills 2
abdominal discomfort 2
groin pain 2
spasticity 2
Decreased activity 1
cyanosis 1
swollen scrotum 1
night sweats 1
bladder pain 1
stridor 1
dystonia 1
syncope 1
nocturnal polyuria 1
Urge incontinence 1
Acute urinary retention 1
emaciation 1
dental pain 1
enuresis 1
arthralgia 1
fever of unknown origin 1
ophthalmoplegia 1
memory loss 1
respiratory distress 1
insomnia 1
heartburn 1
productive cough 1
hemiplegia 1
frequent urination 1
hyperosmia 1
regurgitation 1
astasia 1
hepatosplenomegaly 1
prostatism 1
erythema 1
partial seizure 1
athetosis 1
hypoproteinemia 1
vertigo 1
urethralgia 1
rales 1
physical symptom 1
muscle cramps 1
dark urine 1
chest pain 1
thinning 1
pleuritic chest pain 1
acute abdomen 1
apathy 1
left lower quadrant pain 1
exhaustion 1
No adverse effect 1
tense 1
Drug
PTH 65
Nephron 26
Nephron 26
Potassium citrate 22
Dial 17
Indinavir 12
ascorbate 9
Dermatol 8
lysine 8
citric acid 6
ROC 6
Monit 5
Cinacalcet 5
Indomethacin 4
Cardiovasc 4
PMPA 4
Zonisamide 4
ROS 4
lactose 4
Tenofovir 4
vitamin E 4
NAG 3
DMSA 3
caffeine 3
Hydrochlorothiazide 3
CTX 3
Rasburicase 3
Topamax 2
Fluconazole 2
ampicillin 2
Gabapentin 2
Leaf 2
Tiopronin 2
Fragment 2
Growth hormone 2
Rasburicase 2
Coral 2
Growth hormone 2
Zonegran 2
Crixivan 2
Benazepril hydrochloride 1
Nitisinone 1
Dyazide 1
Plavix 1
Isradipine 1
Infliximab 1
Rimonabant 1
ADR 1
Infliximab 1
Meropenem 1
Rosiglitazone 1
Oseltamivir 1
Rituximab 1
CTX 1
PMEA 1
Gabitril 1
Diamox 1
THF 1
Angiotensin II 1
CTC 1
PTC 1
Denosumab 1
CTX 1
NH3 1
Indapamide 1
Carboxyatractyloside 1
Gabitril 1
Gel 1
Teriparatide 1
CTA 1
Activin 1
Beta-2 1
Indapamide 1
Metolazone 1
Spectrum 1
CTT 1
ATV 1
Coumadin 1
Albumin 1
pyridoxal phosphate 1
CSF 1
Keppra 1
Pyridoxamine 1
Dilantin 1
Glycyrrhiza 1
Amiloride 1
Vitamin B 1
NVP 1
CaCl2 1
Felbatol 1
CTC 1
lomefloxacin hydrochloride 1
Tuberculin 1
Estrogens 1
Colombo 1
Calcium chloride 1
Captopril 1
Ammonium chloride 1
EHDP 1
LFLX 1
Amiloride 1
Lotrel 1
Asthma 1
Clopidogrel 1
DPA 1
Meropenem 1
Oxaprozin 1
Phenytoin 1
Alanine 1
URF 1
Enzyme
alkaline phosphatase 25
ATPase 18
lactate dehydrogenase 17
superoxide dismutase 15
carbonic anhydrase 15
urease 14
urease 14
hypoxanthine-guanine phosphoribosyltransferase 11
renin 11
catalase 11
xanthine oxidase 10
AGT 9
adenine phosphoribosyltransferase 8
xanthine dehydrogenase 7
gamma-glutamyl transpeptidase 6
reverse transcriptase 6
uricase 5
ACE 5
peroxidase 5
NADPH oxidase 5
NADPH oxidase 5
glyoxylate reductase 4
calcineurin 4
glutathione peroxidase 4
glyoxylate reductase 4
HK2 3
mitogen-activated protein kinase 3
creatine kinase 3
luciferase 3
focal adhesion kinase 3
thromboplastin 2
homogentisate 1,2-dioxygenase 2
glycolate oxidase 2
thrombin 2
caspase-3 2
pyruvate dehydrogenase 2
pyruvate dehydrogenase 2
caspase-9 2
ERK 2
endonuclease 2
hydroxypyruvate reductase 2
hexosaminidase 2
protein kinase 2
hydroxypyruvate reductase 2
PNL 2
lysozyme 2
pyruvate dehydrogenase 2
protein kinase C 2
acid phosphatase 1
PAT 1
DCF 1
nucleotide pyrophosphatase 1
hyaluronidase 1
cystathionine beta-synthase 1
leucine aminopeptidase 1
alanine aminopeptidase 1
ceruloplasmin 1
RNase 1
FAST 1
alpha-glucosidase 1
phospholipase A2 1
glutathione reductase 1
CD13 1
4-hydroxy-2-oxoglutarate aldolase 1
oxalate oxidase 1
RNase 1
prolyl endopeptidase 1
hyaluronidase 1
urokinase-type plasminogen activator 1
oxalate decarboxylase 1
AMP-activated protein kinase 1
PRPP synthetase 1
alanine aminotransferase 1
cathepsin K 1
oligopeptidase B 1
paraoxonase 1
lactic acid dehydrogenase 1
4-hydroxyphenylpyruvate dioxygenase 1
glucose-6-phosphatase 1
1-hydroxylase 1
complex I 1
citrate lyase 1
adenylate cyclase 1
IMP dehydrogenase 1
DNA polymerase 1
diacylglycerol kinase 1
MsrA 1
aldolase 1
CGT 1
phosphodiesterase 1
Compound
calcium 1013
oxalate 557
phosphate 254
Clin 251
Dec 180
sodium 179
creatinine 157
potassium 145
water 114
vitamin D 95
ammonium 65
PEG 55
PEG 52
salt 49
phosphorus 49
oxalic acid 42
carbonate 39
DNA 36
sulfate 35
His 34
urea 32
glucose 29
Uric acid 28
CIT 23
hydrogen 22
oxygen 19
nitrogen 18
Dial 17
arginine 17
Vitamin D 16
cAMP 16
sodium chloride 14
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
aldosterone 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
Topiramate 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
oxalic acid 13
ammonia 13
HPP 12
Indinavir 12
AMP 12
lysine 11
galactose 10
Mg2+ 9
Thiazide 8
proline 8
TOF 7
hydroxide 7
zinc 7
Cystine 7
ornithine 7
ornithine 7
ornithine 7
ornithine 7
DHA 7
Melamine 7
ornithine 7
25-dihydroxycholecalciferol 7
DHA 6
8-OHdG 6
DHA 6
HCO 6
nitric oxide 6
MDA 6
Cystine 6
bromide 5
TNF 5
methionine 5
GSH 5
HPT 5
acetate 5
GSH 5
Ceftriaxone 5
Salix 5
leucine 5
alanine 5
CO2 5
aluminum 5
iron 5
PH2 5
nicotinamide 5
Hydrochlorothiazide 4
methanol 4
cysteine 4
CAT 4
Xanthine 4
Asp 4
Insulin 4
CAT 4
phosphoric acid 4
Zonisamide 4
cadmium 4
CAT 4
Salt 4
N-acetylcysteine 3
THP 3
PPi 3
EDTA 3
Sodium 3
aspartic acid 3
COS 3
CTX 3
6-12 3
EDTA 3
glutamate 3
tyrosine 3
aspartic acid 3
ALP 3
aspartic acid 3
THP 3
aspartic acid 3
Indomethacin 3
cyanide 3
caffeine 3
copper 3
serine 3
MTT 3
ethanol 3
tryptophan 3
Triamterene 3
Ile 3
ATP 3
Parenteral 2
Formal 2
SDA 2
DTPA 2
Collagen 2
superoxide radical 2
aldehyde 2
hyaluronic acid 2
selenium 2
Neu5Ac 2
Ritonavir 2
Taurine 2
SCC 2
MgO 2
ACTH 2
TAR 2
silver 2
aldehyde 2
DSM 2
PGE2 2
boron 2
Gly 2
Tannin 2
Indinavir sulfate 2
Glyoxylate 2
more...