Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0392326 (discomfort)
 22,423 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinically significant thromboembolic disease originating from the paralyzed leg of hemiplegic patients can occur unexpectedly and may affect morbidity and mortality in the rehabilitation setting. Impedance plethysmography (IPG), a simple, noninvasive technique, can accurately reveal deep vein thrombosis (DVT) in the large veins of the thigh. IPG studies were performed on the lower extremities of 20 hemiplegic patients considered at high risk for DVT. Each patient had one or several of the following potential risk factors: mild swelling, vague leg discomfort, loss of sensation, poor or absent muscle power at the ankle, at least one week of complete bedrest, repeated minor trauma. None of the patients had major signs or symptoms of DVT at the time of testing (ie, severe pain and tenderness, increased temperature or redness, a palpable venous cord, or positive Homans' sign). Seven patients had an abnormal IPG in the paralyzed lower limb and DVT was confirmed in each case by venography. After appropriate anticoagulation therapy, the seven patients resumed their rehabilitation programs. It was concluded that IPG can be successfully used in the early detection of DVT in high-risk hemiplegic patients, thus leading to prompt medical management, reduced morbidity and mortality, and improved rehabilitation outcome.
 ...
PMID:Deep venous thrombosis in high-risk hemiplegic patients: detection by impedance plethysmography. 377 73