UMLS:C0376358 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C0376358 (prostate cancer)
59,338 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
prostate-specific antigen	5249
androgen receptor	4753
Sep	3796
Mol	3784
PC-3	3476
PSA	2886
PC3	2685
prostate specific antigen	1567
p53	1251
MRI	1056
prostate-specific membrane antigen	975
caspase-3	753
Bcl-2	752
AKT	723
Men	693
PTEN	684
p21	612
PI3K	599
ERG	594
prostatic acid phosphatase	525
cytokine	506
E-cadherin	506
mTOR	506
TMPRSS2	503
histone	486
insulin	454
LHRH	441
vascular endothelial growth factor	418
Androgen receptor	402
PSMA	398
estrogen receptor	391
cyclin D1	388
reductase	379
PARP	359
nodal	358
NMR	356
MAPK	339
catenin	321
epidermal growth factor receptor	316
tyrosine kinase	302
p27	301
cage	298
ERK	297
acid phosphatase	289
ERK1	286
proteasome	274
AR protein	272
alkaline phosphatase	271
collagen	271
endoplasmic reticulum	270
TRAMP	264
epidermal growth factor	259
p38	259
insulin-like growth factor	256
CD44	251
matrix metalloproteinase	246
Ki-67	244
VEGF	244
c-Myc	244
tumor necrosis factor	238
MMP-9	237
vimentin	233
nuclear receptor	232
STAT3	231
IL-6	227
phosphatase	225
FGF8	224
BRCA1	222
glycoprotein	219
ATP	219
caspase-9	216
BRCA2	214
EGFR	211
histone deacetylase	208
survivin	205
serine protease	204
annexin V	204
CD8	202
UTR	198
interleukin-6	194

Disease
prostate cancer	59338
cancer	28040
tumor	15437
metastases	4693
breast cancer	3352
Prostate Cancer	3281
carcinoma	3194
PSA	2886
tumor growth	2340
carcinogenesis	1908
adenocarcinoma	1896
tumor progression	1876
tumorigenesis	1600
bone metastases	1376
lung cancer	1252
melanoma	908
aggressiveness	883
prostatic adenocarcinoma	877
PIN	808
bladder cancer	787
colorectal cancer	726
leukemia	633
colon cancer	613
primary tumor	541
ovarian cancer	538
diabetes	517
obesity	476
renal cell carcinoma	458
osteoporosis	440
incontinence	440
MCF	433
prostatic disease	419
erectile dysfunction	393
hepatocellular carcinoma	386
multiple myeloma	384
prostatitis	374
pancreatic cancer	356
gastric cancer	349
seminal vesicles	326
cervical cancer	318
renal cancer	312
cardiovascular disease	281
incontinence	269
hypertension	267
lymphoma	264
SCID	250
non-small cell lung cancer	244
depression	238
recurrent prostate cancer	237
urethra	224
skin cancer	218
liver cancer	208
squamous cell carcinoma	206
hormone refractory prostate cancer	201
hypogonadism	194
testicular cancer	190
glioblastoma	190
liver cancer	186
glioma	186
metabolic syndrome	184
tumor angiogenesis	180
bone disease	180
impotence	172
retinoblastoma	162
anemia	161
solid tumor	157
Hodgkin's disease	156
type 2 diabetes	154
endometrial cancer	150
osteosarcoma	143
ATM	138
neuroblastoma	138
PIN	134
HIV	133
gynecomastia	131
sexual dysfunction	130
spinal cord compression	125
thyroid cancer	122
tumor initiation	120
stroke	119

Symptom
pain	1010
bone pain	289
fatigue	276
diarrhea	143
anesthesia	124
hot flashes	114
nausea	105
hot flushes	85
overweight	81
discomfort	77
dysuria	77
discomfort	70
starvation	63
weakness	58
vomiting	58
headache	53
anorexia	50
back pain	47
dyspnea	46
abdominal pain	43
analgesia	41
pelvic pain	38
nausea and vomiting	36
prostatism	36
cachexia	36
constipation	26
collapse	25
seizures	25
cancer pain	22
low back pain	22
urinary frequency	21
exhaustion	19
Ill	19
chills	19
cough	17
acidity	17
menopausal symptoms	16
masculinization	15
erythema	15
flushing	14
stigma	14
asthenia	14
sleepiness	13
ataxia	13
insomnia	13
dizziness	12
paresis	11
numbness	11
angina	11
tremor	11
myalgia	11
lethargy	10
chest pain	10
hip pain	10
flank pain	9
Lower urinary tract symptoms	8
shortness of breath	8
arthralgia	8
functional recovery	8
tenesmus	8
Acute urinary retention	7
leg edema	7
hepatomegaly	7
Urinary symptoms	6
leg pain	6
mastalgia	6
exertional dyspnea	6
rectal pain	5
decreased appetite	5
paresthesia	5
ophthalmoplegia	5
oliguria	5
fever of unknown origin	5
Wind	5
agitation	5
penile lesion	5
paraparesis	5
blurred vision	5
skin irritation	5
night sweats	5

Enzyme
prostate-specific antigen	4866
prostate-specific membrane antigen	1110
mitogen-activated protein kinase	1029
ERK	964
luciferase	647
caspase-3	586
protein kinase	523
focal adhesion kinase	463
PARP	398
acid phosphatase	293
proteasome	279
alkaline phosphatase	273
protein kinase C	228
urokinase-type plasminogen activator	208
MEK	201
reverse transcriptase	191
ACS	184
kallikrein	177
caspase-9	175
caspase-8	152
phosphatidylinositol 3-kinase	151
glutathione S-transferase	148
AMP-activated protein kinase	136
5alpha-reductase	133
5alpha-reductase	132
cdc2	131
lactate dehydrogenase	103
phosphoinositide 3-kinase	102
ATPase	97
catalase	96
RNA polymerase	93
peroxidase	91
AMPK	91
GSK	88
AMPK	82
topoisomerase	79
APC	77
trypsin	77
MAT	74
MAT	74
topoisomerase	73
superoxide dismutase	72
thymidine kinase	70
collagenase	70
phosphodiesterase	70
DNA methyltransferase	66
calcineurin	66
MMP	66
P-glycoprotein	65
CYP3A4	61
MDP	60
phospholipase C	58
hepsin	55
hepsin	55
IKK	53
RNase	52
RNase	51
alpha-methylacyl-CoA racemase	51
glutathione peroxidase	49
HDR	49
demethylase	48
lipoxygenase	44
beta-galactosidase	41
CD10	40
ornithine decarboxylase	39
cathepsin B	38
thrombin	38
alanine aminotransferase	37
histone acetyltransferase	36
aspartate aminotransferase	36
matrix metalloproteinase 9	36
transcriptase	36
matriptase	35
NQO1	35
matrix metalloproteinase 2	35
tissue kallikrein	35
NADPH oxidase	34
MAP	33
phospholipase A2	33
protein phosphatase 2A	33