Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0349506 (photosensitivity)
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Human Gene/Protein
piggyBac transposable element derived 3 12.9
FAM78A protein 12.9
Chromodomain-helicase-DNA-binding protein 2 12.9
C7orf11 11.9
KIAA1530 11.9
Retinitis pigmentosa 1 11.9
FERMT1 11.5
TTDN1 11.3
retinal G protein coupled receptor 11.3
5-aminolevulinate synthase 2 11.3
MAMDC1 11.3
PTCD2 11.3
Complement component 2 11.3
Kindlin-1 11.1
eyes absent 3 10.9
ACTIN-2 10.9
pFIV 10.9
FECH 10.8
ERCC8 10.8
kindlin-1 10.7
protoporphyria 10.6
PTCD3 10.6
uroporphyrinogen-III synthase 10.6
Hermansky-Pudlak syndrome type 1 10.6
GTF2H5 10.4
Golgi SNAP 10.3
MRPS27 10.3
PPOX 10.2
uroporphyrinogen III synthase 9.9
Von Willebrand factor-cleaving protease 9.9
retinol dehydrogenase 5 9.9
trichothiodystrophy 9.9
UROD 9.8
PTCD1 9.7
ferrochelatase 9.6
FBP21 9.6
variegate porphyria 9.6
MITOCHONDRIAL 9.5
MDC2 9.4
OTUD4 9.4
ribonuclease H2 9.4
ERCC6 9.4
HTRA3 9.3
NMO1 9.3
ALAS2 9.2
RNF113A 9.1
rgr 9.1
RLP1 9.1
PHK 9.0
MYM 8.9
melanopsin 8.8
GRSF1 8.8
transcription factor II H 8.8
RP1L1 8.8
protoporphyrinogen oxidase 8.8
CNK1 8.7
C1QC 8.7
SECISBP2 8.7
CHD2 8.6
OPN5 8.6
TPCN2 8.6
CSB 8.5
PXK 8.5
SMEI 8.5
TFIIE-beta 8.5
PCDH19 8.4
coproporphyrinogen oxidase 8.4
podocalyxin-like protein 8.4
HLA-A33 8.3
SLC15A4 8.3
PTC7 8.3
POLH 8.2
RAD26 8.2
Ferrochelatase 8.1
C1QB 8.1
SNM1A 8.1
Bloom syndrome 8.1
TIP41 8.0
Protoporphyrinogen oxidase 8.0
transcription factor TFIIH 8.0
more...
Disease
photosensitivity 12.9
Pure photosensitive epilepsy 12.9
Erythropoietic coproporphyria 12.9
Drug-induced photosensitivity 12.6
Actinic reticuloid 12.4
Homozygous variegate porphyria 12.3
PPR 12.1
Sabinas syndrome 11.9
Photodermatosis 11.9
Alcoholic pellagra 11.9
Diffuse plane xanthomatosis 11.9
Chronic actinic dermatitis 11.8
Hepatoerythropoietic porphyria 11.8
Photoallergic contact dermatitis 11.5
Photosensitive epilepsy 11.5
Ferrochelatase deficiency 11.3
Hydroa vacciniforme 11.0
photoallergy 10.9
Secondary antiphospholipid syndrome 10.9
Pollitt syndrome 10.9
Nodular basal cell carcinoma 10.9
erythropoietic protoporphyria 10.8
brittle hair 10.8
Solar urticaria 10.7
Subacute cutaneous lupus erythematosus 10.7
poikiloderma 10.7
Facial eczema 10.6
Hereditary coproporphyria 10.6
Photo-onycholysis 10.4
Pseudoporphyria 10.4
Actinic prurigo 10.4
Polymorphic light eruption 10.3
Benign myoclonic epilepsy in infancy 10.1
Paraneoplastic retinopathy 10.1
trichothiodystrophy 10.0
Xeroderma 10.0
Erythromelanosis follicularis faciei et colli 9.9
variegate porphyria 9.9
photodermatitis 9.9
Plasma cell infiltration 9.7
facial tic 9.7
coproporphyria 9.7
Corneal deposits 9.6
Lupus erythematosus tumidus 9.6
Cutaneous lupus erythematosus 9.5
Progressive myoclonic epilepsy 9.5
Simple partial seizures 9.4
Phototoxicity 9.3
Cockayne syndrome 9.2
porphyria 9.2
Generalized epilepsy 9.0
ALAD deficiency 9.0
Tinea faciei 9.0
CEP 8.8
AGEP 8.7
Ehlers-Danlos syndrome type II 8.7
hepatic porphyria 8.7
onycholysis 8.7
Coombs positive hemolytic anemia 8.7
Goatpox 8.7
Confluent and reticulate papillomatosis 8.7
Photosensitization 8.6
CSB 8.5
Hypersensitivity syndrome 8.5
CSB 8.5
OCA3 8.4
PPR1 8.4
PPR2 8.4
pellagra 8.4
reflex epilepsy 8.4
porphyria cutanea tarda 8.4
Bacterial endophthalmitis 8.3
flexural dermatitis 8.3
Neutrophilic dermatosis 8.2
Oral ulcers 8.2
Minimal change nephrotic syndrome 8.2
phytophotodermatitis 8.1
Cluster B personality disorder 8.1
viral exanthema 8.1
OCA4 8.1
more...
Symptom
Persistent light reaction 12.3
Corneal blood staining 10.9
Juvenile spring eruption 10.1
Negative myoclonus 9.4
Convergence Insufficiency 7.9
Urticarial vasculitis 7.4
photopsia 7.4
epigastric distress 7.3
Bitot's spots 6.8
erythema 6.8
Skin symptoms 6.8
periorbital edema 6.5
livedo 6.5
photophobia 6.2
skin damage 6.1
Visual symptoms 6.1
myoclonus 6.1
arthralgia 5.9
dark urine 5.8
generalized rash 5.7
tonic-clonic seizure 5.7
scaly skin 5.5
intention tremor 5.5
pachyonychia 5.4
dry skin 5.2
pedal edema 5.2
auditory hallucination 4.9
ataxic gait 4.8
lassitude 4.8
mental fatigue 4.7
partial seizure 4.5
hyperacusis 4.4
seizures 4.3
myalgia 4.2
blurred vision 4.2
dry eye 4.1
muscle cramps 4.1
POA 3.9
nausea 3.8
skin irritation 3.8
hepatosplenomegaly 3.8
decreased appetite 3.7
pleuritic chest pain 3.7
dizziness 3.7
right upper quadrant pain 3.5
ataxia 3.5
flushing 3.3
consciousness disturbance 3.2
chills 3.2
asthenia 3.1
clubbing 3.1
dysesthesia 3.0
insomnia 3.0
hoarseness 3.0
paresthesia 3.0
acute abdominal pain 3.0
otalgia 2.9
twitching 2.9
chorea 2.9
tense 2.8
hypoproteinemia 2.8
constipation 2.8
hepatomegaly 2.7
fatigue 2.7
night sweats 2.7
abdominal pain 2.7
Ill 2.6
anorexia 2.6
tingling 2.6
headache 2.6
paraparesis 2.5
paresis 2.4
discomfort 2.4
diarrhea 2.3
physical appearance 2.3
spasticity 2.2
discomfort 2.2
splenomegaly 2.2
hypocapnia 2.2
epigastric pain 2.2
more...
Drug
Oraflex 12.9
Ampiroxicam 10.9
Talaporfin sodium 10.9
Levulan 10.3
Afloqualone 9.7
Photofrin II 9.6
Bufexamac 9.4
Eusolex 9.3
Quinine sulfate 9.2
Eusolex 9.2
Compazine 8.8
Parsol 8.7
lomefloxacin hydrochloride 8.6
Photofrin 8.6
Verteporfin 8.5
Pirfenidone 8.5
Periactin 8.4
Compazine 8.3
Periactin 8.3
Minocin 8.1
Rabies vaccine 8.0
Zithromax 8.0
Thioguanine 7.9
Vandetanib 7.8
Methyl aminolevulinate 7.7
Seldane 7.7
Ambien 7.6
DOXY 7.2
Tenidap 7.1
Zoloft 6.8
Malarone 6.8
Velban 6.7
Acitretin 6.7
CPFX 6.7
Vibramycin 6.7
TFT 6.5
Anagrelide 6.4
Gatifloxacin 6.4
Valproic Acid 6.4
Nabumetone 6.3
Pefloxacin 6.3
Perphenazine 6.2
Anafranil 6.2
Lipitor 6.1
Lipitor 6.1
Hydergine 6.1
Pimecrolimus 6.0
ALA 6.0
Roflumilast 5.9
Roflumilast 5.9
Kelp 5.9
Clobetasol propionate 5.7
Dithranol 5.6
Fenbendazole 5.6
Methyldopa 5.6
Sodium valproate 5.6
Isotretinoin 5.5
Flavin 5.5
Dronedarone 5.5
Prograf 5.5
Carotenoid 5.4
all-trans-retinol 5.3
Bactrim 5.3
Ipilimumab 5.2
Pramipexole 5.2
Poloxamer 5.2
Pramipexole 5.2
Atovaquone 5.1
Moxifloxacin 5.0
OIF 4.9
Doxycycline 4.8
Bezafibrate 4.8
CPO 4.7
CPZ 4.6
Clomiphene citrate 4.6
Piracetam 4.5
Caspofungin 4.5
Camp 4.4
Retinoic Acid 4.3
Trimethoprim-sulfamethoxazole 4.3
more...
Enzyme
EC 2.3.1.27 12.9
ferrochelatase 9.6
porphobilinogenase 9.4
retinol isomerase 9.0
protoporphyrinogen oxidase 8.5
uroporphyrinogen decarboxylase 8.4
coproporphyrinogen oxidase 8.1
neuropsin 7.8
violaxanthin de-epoxidase 7.4
7-dehydrocholesterol reductase 7.3
neuropsin 7.2
coproporphyrinogen III oxidase 6.4
porphobilinogen deaminase 6.2
prolinase 5.8
formyltetrahydrofolate synthetase 5.8
thymidylate kinase 5.7
ALA synthase 5.5
CEP 5.4
dUTPase 5.2
PPH 5.0
CEP 4.8
arylalkylamine N-acetyltransferase 4.5
propionyl-CoA carboxylase 4.5
propionyl-CoA carboxylase 4.5
ficin 4.5
phospholipid hydroperoxide glutathione peroxidase 4.4
rhodopsin kinase 4.3
succinyl-CoA synthetase 4.2
phosphorylase kinase 4.1
PRE 4.0
prolidase 4.0
NADH dehydrogenase 3.8
dehydroascorbate reductase 3.8
meprin 3.8
MTD 3.7
monoacylglycerol lipase 3.5
cytochrome c peroxidase 3.5
dopamine beta-hydroxylase 3.5
SOR 3.4
deoxyribonuclease 3.4
rhodanese 3.4
complex I 3.4
ClpP 3.3
N-acetyltransferase 3.3
peptidyl-prolyl cis-trans isomerase 3.3
acyl-CoA dehydrogenase 3.3
MDH 3.3
MDH 3.2
LasR 3.1
delta-aminolevulinic acid dehydratase 3.1
interstitial collagenase 3.0
ACS 2.9
SCS 2.9
bromelain 2.9
flavin-containing monooxygenase 2.8
3-hydroxy-3-methylglutaryl-CoA reductase 2.8
RNase P 2.5
DNA ligase 2.5
DNA ligase 2.5
tryptase 2.5
heme oxygenase 2.5
acyl-CoA dehydrogenase 2.4
indoleamine 2,3-dioxygenase 2.4
aequorin 2.4
glucocerebrosidase 2.4
diaphorase 2.4
Mg2+-ATPase 2.4
PAL 2.3
glyceraldehyde-3-phosphate dehydrogenase 2.2
MEK 2.2
chloramphenicol acetyltransferase 2.2
aconitase 2.1
DCF 2.0
succinate dehydrogenase 1.9
RNA polymerase 1.9
CYP3A4 1.9
MMP 1.9
PAL 1.8
glutamate decarboxylase 1.8
cytochrome oxidase 1.8
more...
Compound
Cyanuric triazide 11.9
Tetrachlorosalicylanilide 10.6
Musk ambrette 10.1
Uroporphyrinogen III 9.9
uroporphyrin I 9.8
Quinoxaline 1,4-dioxide 9.4
Photofrin II 9.2
Compazine 9.0
Foscan 8.8
Benoxaprofen 8.7
Grepafloxacin 8.6
Eusolex 8.6
Sparfloxacin 8.3
THPC 8.1
Michler's ketone 7.8
Lentizol 7.7
Amiodarone hydrochloride 7.7
Azapropazone 7.7
Lomefloxacin 7.7
Minocycline hydrochloride 7.7
Mequitazine 7.7
Mequitazine 7.7
Mequitazine 7.7
1,2,4,5-benzenetetracarboxylic acid 7.7
Girard's reagent T 7.7
Mequitazine 7.7
Oltipraz 7.6
1,2,4,5-benzenetetracarboxylic acid 7.6
Protoporphyrin IX 7.5
Porphyrin 7.5
11-cis-retinal 7.4
Porphyrin 7.4
Protochlorophyllide 7.4
PDT 7.4
Nafoxidine 7.4
Voriconazole 7.4
Ethylketocyclazocine 7.3
merocyanine 540 7.3
2,5-dimethylfuran 7.3
Quine 7.3
Fleroxacin 7.2
Tolmetin 7.1
iodic acid 7.1
8-MOP 7.1
delta-aminolevulinic acid 7.0
Velban 7.0
threonate 7.0
Suprofen 6.9
6-Thioguanine 6.9
Choline chloride 6.8
Dettol 6.8
Amiodarone 6.6
butylbenzene 6.6
DHC 6.6
Piroxicam 6.6
Ketoprofen 6.5
BPQ 6.5
Photodyn 6.5
Gatifloxacin 6.5
Griseofulvin 6.5
Dihydroxyacetone 6.5
Griseofulvin 6.5
TFT 6.4
Etorphine 6.4
Phenothiazine 6.4
IGE 6.4
MOP 6.3
Primidone 6.3
Hypericin 6.3
Rhodopsin 6.3
Diallyl disulfide 6.2
Diallyl disulfide 6.2
Psoralen 6.2
Potassium permanganate 6.2
Chlorite 6.1
Dibucaine 6.0
PBG 6.0
Terfenadine 6.0
MoSe2 5.9
benzophenone 5.9
more...