Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0349506 (photosensitivity)
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Human Gene/Protein
piggyBac transposable element derived 3 12.9
FAM78A protein 12.9
Chromodomain-helicase-DNA-binding protein 2 12.9
KIAA1530 11.9
Retinitis pigmentosa 1 11.9
C7orf11 11.9
FERMT1 11.5
TTDN1 11.3
PTCD2 11.3
Complement component 2 11.3
retinal G protein coupled receptor 11.3
MAMDC1 11.3
5-aminolevulinate synthase 2 11.3
Kindlin-1 11.1
pFIV 10.9
ACTIN-2 10.9
eyes absent 3 10.9
FECH 10.8
ERCC8 10.8
kindlin-1 10.7
protoporphyria 10.6
uroporphyrinogen-III synthase 10.6
Hermansky-Pudlak syndrome type 1 10.6
PTCD3 10.6
GTF2H5 10.4
MRPS27 10.3
Golgi SNAP 10.3
PPOX 10.2
uroporphyrinogen III synthase 9.9
Von Willebrand factor-cleaving protease 9.9
retinol dehydrogenase 5 9.9
trichothiodystrophy 9.9
UROD 9.8
PTCD1 9.7
ferrochelatase 9.6
FBP21 9.6
variegate porphyria 9.6
MITOCHONDRIAL 9.5
ribonuclease H2 9.4
MDC2 9.4
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Disease
photosensitivity 12.9
Erythropoietic coproporphyria 12.9
Pure photosensitive epilepsy 12.9
Drug-induced photosensitivity 12.6
Actinic reticuloid 12.4
Homozygous variegate porphyria 12.3
PPR 12.1
Alcoholic pellagra 11.9
Sabinas syndrome 11.9
Diffuse plane xanthomatosis 11.9
Photodermatosis 11.9
Chronic actinic dermatitis 11.8
Hepatoerythropoietic porphyria 11.8
Photoallergic contact dermatitis 11.5
Photosensitive epilepsy 11.5
Ferrochelatase deficiency 11.3
Hydroa vacciniforme 11.0
photoallergy 10.9
Secondary antiphospholipid syndrome 10.9
Nodular basal cell carcinoma 10.9
Pollitt syndrome 10.9
erythropoietic protoporphyria 10.8
brittle hair 10.8
Solar urticaria 10.7
Subacute cutaneous lupus erythematosus 10.7
poikiloderma 10.7
Hereditary coproporphyria 10.6
Facial eczema 10.6
Photo-onycholysis 10.4
Pseudoporphyria 10.4
Actinic prurigo 10.4
Polymorphic light eruption 10.3
Benign myoclonic epilepsy in infancy 10.1
Paraneoplastic retinopathy 10.1
trichothiodystrophy 10.0
Xeroderma 10.0
Erythromelanosis follicularis faciei et colli 9.9
variegate porphyria 9.9
photodermatitis 9.9
facial tic 9.7
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Symptom
Persistent light reaction 12.3
Corneal blood staining 10.9
Juvenile spring eruption 10.1
Negative myoclonus 9.4
Convergence Insufficiency 7.9
Urticarial vasculitis 7.4
photopsia 7.4
epigastric distress 7.3
Bitot's spots 6.8
erythema 6.8
Skin symptoms 6.8
periorbital edema 6.5
livedo 6.5
photophobia 6.2
skin damage 6.1
Visual symptoms 6.1
myoclonus 6.1
arthralgia 5.9
dark urine 5.8
generalized rash 5.7
tonic-clonic seizure 5.7
scaly skin 5.5
intention tremor 5.5
pachyonychia 5.4
dry skin 5.2
pedal edema 5.2
auditory hallucination 4.9
ataxic gait 4.8
lassitude 4.8
mental fatigue 4.7
partial seizure 4.5
hyperacusis 4.4
seizures 4.3
myalgia 4.2
blurred vision 4.2
dry eye 4.1
muscle cramps 4.1
POA 3.9
nausea 3.8
skin irritation 3.8
more...
Drug
Oraflex 12.9
Talaporfin sodium 10.9
Ampiroxicam 10.9
Levulan 10.3
Afloqualone 9.7
Photofrin II 9.6
Bufexamac 9.4
Eusolex 9.3
Quinine sulfate 9.2
Eusolex 9.2
Compazine 8.8
Parsol 8.7
lomefloxacin hydrochloride 8.6
Photofrin 8.6
Verteporfin 8.5
Pirfenidone 8.5
Periactin 8.4
Compazine 8.3
Periactin 8.3
Minocin 8.1
Rabies vaccine 8.0
Zithromax 8.0
Thioguanine 7.9
Vandetanib 7.8
Methyl aminolevulinate 7.7
Seldane 7.7
Ambien 7.6
DOXY 7.2
Tenidap 7.1
Zoloft 6.8
Malarone 6.8
Velban 6.7
Acitretin 6.7
CPFX 6.7
Vibramycin 6.7
TFT 6.5
Anagrelide 6.4
Gatifloxacin 6.4
Valproic Acid 6.4
Nabumetone 6.3
more...
Enzyme
EC 2.3.1.27 12.9
ferrochelatase 9.6
porphobilinogenase 9.4
retinol isomerase 9.0
protoporphyrinogen oxidase 8.5
uroporphyrinogen decarboxylase 8.4
coproporphyrinogen oxidase 8.1
neuropsin 7.8
violaxanthin de-epoxidase 7.4
7-dehydrocholesterol reductase 7.3
neuropsin 7.2
coproporphyrinogen III oxidase 6.4
porphobilinogen deaminase 6.2
prolinase 5.8
formyltetrahydrofolate synthetase 5.8
thymidylate kinase 5.7
ALA synthase 5.5
CEP 5.4
dUTPase 5.2
PPH 5.0
CEP 4.8
arylalkylamine N-acetyltransferase 4.5
propionyl-CoA carboxylase 4.5
propionyl-CoA carboxylase 4.5
ficin 4.5
phospholipid hydroperoxide glutathione peroxidase 4.4
rhodopsin kinase 4.3
succinyl-CoA synthetase 4.2
phosphorylase kinase 4.1
PRE 4.0
prolidase 4.0
NADH dehydrogenase 3.8
dehydroascorbate reductase 3.8
meprin 3.8
MTD 3.7
monoacylglycerol lipase 3.5
cytochrome c peroxidase 3.5
dopamine beta-hydroxylase 3.5
SOR 3.4
deoxyribonuclease 3.4
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Compound
Cyanuric triazide 11.9
Tetrachlorosalicylanilide 10.6
Musk ambrette 10.1
Uroporphyrinogen III 9.9
uroporphyrin I 9.8
Quinoxaline 1,4-dioxide 9.4
Photofrin II 9.2
Compazine 9.0
Foscan 8.8
Benoxaprofen 8.7
Grepafloxacin 8.6
Eusolex 8.6
Sparfloxacin 8.3
THPC 8.1
Michler's ketone 7.8
Amiodarone hydrochloride 7.7
Lentizol 7.7
Azapropazone 7.7
Lomefloxacin 7.7
Minocycline hydrochloride 7.7
Girard's reagent T 7.7
1,2,4,5-benzenetetracarboxylic acid 7.7
Mequitazine 7.7
Mequitazine 7.7
Mequitazine 7.7
Mequitazine 7.7
Oltipraz 7.6
1,2,4,5-benzenetetracarboxylic acid 7.6
Protoporphyrin IX 7.5
Porphyrin 7.5
11-cis-retinal 7.4
Porphyrin 7.4
Protochlorophyllide 7.4
PDT 7.4
Voriconazole 7.4
Nafoxidine 7.4
Ethylketocyclazocine 7.3
merocyanine 540 7.3
2,5-dimethylfuran 7.3
Quine 7.3
more...