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Query: UMLS:C0348321 (Haemophilus)
 15,372 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

White, David C. (The Rockefeller Institute, New York, N. Y.) Cytochrome and catalase patterns during growth of Haemophilus parainfluenzae. J. Bacteriol. 83:851-859. 1962.-By following the cytochrome and catalase concentrations during the growth cycle and under various growth conditions in Haemophilus parainfluenzae, a rapid increase in the cytochrome oxidases and a large increase in cytochrome c(1) concentration can be demonstrated between log-phase and stationary-phase cells and between vigorously aerated and anaerobic growth conditions. The three cytochrome oxidases develop differentially under various growth conditions. The principal oxidase formed in vigorously aerated cultures is cytochrome o. With limited aeration, maximal development of cytochrome a(2) occurs; with anaerobically grown cells, there is a marked increase in the concentration of cytochrome a(1). With the rapid increase in cytochrome c(1) concentration, soluble, nonenzymatically reducible cytochrome c(1) is also formed, which remains in the bacterial cell sap. From these data it is postulated that the electron-transport system is assembled from individual components which can be modified by the growth conditions. The cytochrome c(1) may be synthesized in the cell sap and then incorporated into the electron-transport system.
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PMID:Cytochrome and catalase patterns during growth of Haemophilus parainfluenzae. 1400 6

Hemophilus pleuropneumoniae, the causative agent of porcine contagious pleuropneumonia (PCP) is an encapsulated organism that has the metabolic features of the parainfluenza group of Hemophilus in that it requires DPN but not hemin for growth. Its formation of nitrate reductase cytochrome a(1) and non-physiologically reducible cytochrome c(1) in the stationary phase, together with its requirement of electron transport through oxidases for growth are typical of non-hemin-requiring Hemophilus species. It has the closest genetic homology, judged from the capacity of its DNA to induce transformation to streptomycin resistance, with H. parasuis but can be differentiated from this organism on the basis of its growth in defined medium and its marked and characteristic pathogenicity for swine.
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PMID:PORCINE CONTAGIOUS PLEUROPNEUMONIA. 3. INTERRELATIONSHIP OF HEMOPHILUS PLEUROPNEUMONIAE TO OTHER SPECIES OF HEMOPHILUS: NUTRITIONAL, METABOLIC, TRANSFORMATION, AND ELECTRON MICROSCOPY STUDIES. 1419 90

White, David C. (University of Kentucky College of Medicine, Lexington). Synthesis of 2-demethyl vitamin K(2) and the cytochrome system in Haemophilus. J. Bacteriol. 89:299-305. 1965.-The synthesis of the respiratory quinone, 2-demethyl vitamin K(2), is stimulated in Haemophilus parainfluenzae under conditions which provoke the synthesis of the cytochrome system. However, the various components of the electron-transport system can be formed in different proportions. The primary flavoprotein dehydrogenases are readily dissociated from the membrane without affecting the content of membrane-bound quinone, cytochrome b(1), or the cytochrome oxidases. These dehydrogenases must be membrane-bound to function, and each can be formed at a different rate. Molar ratios of various constituents of the electron-transport chain were calculated by use of reasonable extinction coefficients for the cytochromes. The molar ratio of quinone to cytochrome c(1) goes from 40 to 3 as the quinone content increases eightfold during the growth cycle. Similarly, the molar ratio of quinone to cytochrome oxidase a(2) varies from 27 to 17, and then increases to 31 as cytochrome oxidase a(1) assumes the oxidase function. The molar ratio of quinone to cytochrome b(1) remains 14 to 1 over a sixfold increase in both components measured in a mutant where cytochrome c(1) does not obscure cytochrome b(1). A similar consistency was noted between the quinone and cytochrome b(1) formation in the hemin-requiring H. influenzae.
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PMID:SYNTHESIS OF 2-DEMETHYL VITAMIN K2 AND THE CYTOCHROME SYSTEM IN HAEMOPHILUS. 1425 94


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