Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0348321 (Haemophilus)
 15,372 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Under general anaesthesia cultures were taken from infantile tonsils prior to T & A. The bacteriological results and the serological classification of hemophilus are questionning literature reports. According to our findings one must consider haemophilus influencae as a resident of the common oral flora. There was no significant difference culturing tonsils with or without repeated antibiotic treatment. Hemophilus influencae combined with beta-hemolytic streptococci is common. Immunological considerations against infantile T & A, based on bacteriological observations are questioned.
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PMID:[Bacteriological findings in chronic infantile tonsillitis (author's transl)]. 14 63

Attachment of bacteria to nonciliated cells of the nasopharyngeal epithelium was evaluated by immunofluorescence assay in 25 otitis-prone and 25 non-otitis-prone children undergoing ear, nose, or throat surgery under general anesthesia. The bacterial findings were analyzed simultaneously, both qualitatively and quantitatively. In otitis-prone children, there was a significant preponderance of epithelial cells having greater than 50 attached bacteria (P less than .001) and of epithelial cells with attached Streptococcus pneumoniae and Haemophilus influenzae (P less than .05). Also, the occurrence of Branhamella catarrhalis in the nasopharynx was more pronounced in the otitis-prone group (P less than .05). No significant differences in the occurrence of other middle ear pathogens or quantitative dominance of pathogens were noted between the two groups. Abundant attachment of pathogens to the epithelial cells close to the nasopharyngeal orifice of the eustachian tube is of a significant factor for the development of the otitis-prone condition.
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PMID:Abundant attachment of bacteria to nasopharyngeal epithelium in otitis-prone children. 158 37

Twenty one children with asthma aged 1.0-10.5 years (mean (SD) 3.3 (2.5) years) were admitted to the hospital to evaluate pulmonary right middle lobe or lingular collapse lasting one to 12 months (mean (SD) 4.4 (3.8) months). Seven children had mild asthma and were treated with inhaled beta 2 agonists as needed. Nine had moderate asthma treated with either sodium cromoglycate or slow release theophylline. Five had severe asthma treated with inhaled steroids. Each child underwent fibreoptic bronchoscopy under local anaesthesia and a bronchoalveolar lavage. Differential cell counts of the lavage fluid revealed predominance of neutrophils in 12 patients (57%). In nine of these patients cultures grew pathogenic bacteria, mainly Haemophilus influenzae and Streptococcus pneumoniae. There was no correlation between the severity of asthma and a positive bacterial culture. There was also no correlation between the duration of the right middle lobe collapse and a positive culture. We conclude that longstanding right middle lobe collapse in asthmatic children is often associated with bacterial infection.
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PMID:Role of infection in the middle lobe syndrome in asthma. 159 94

Acute epiglottitis caused by Haemophilus influenzae type B (Hib) is seldom described in Chile. To reinforce the need to take this severe entity into account in the differential diagnosis of acute upper respiratory tract obstructions, the case of a 9 month old girl is described, who's symptoms were initially attributed to acute laryngitis, but showed not response to racemic epinephrine and betamethasone therapy. The correct diagnosis of acute epiglottitis was suggested five hours after admission by lateral neck's radiographs and confirmed by direct laryngoscopic examination under general anesthesia. Appropriate treatment was soon instituted including tracheal intubation respiratory support and antibiotics. An uneventful clinical course proceeded from then on. Hemophilus influenzae B was isolated from blood cultures.
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PMID:[Acute epiglottitis]. 184 65

We studied fluid obtained from middle ear effusions (MEEs) during 908 myringotomy and tube insertion procedures on 495 children aged 4 months to 12 years. Under general anesthesia the external auditory canal was sterilized with povidone-iodine (Betadine) and alcohol, and myringotomy was done. Fluid was aspirated into a Luki tube and sent for culture and sensitivity determination. The median age of patients was 3 years 5 months; 1-year-old children comprised the largest single group. Two thirds of the children were male. Effusion was present in three fourths of the ears; in about 20% of these, culture grew bacteria. Haemophilus influenzae made up almost 50% of the pathogens, with the percentage decreasing with age. Almost 90% of the H influenzae organisms were sensitive to erythromycin, and about three fourths to ampicillin and cephalosporin.
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PMID:Bacteriology of middle ear effusions. 327 31

Fifteen per cent of patients admitted to a male general surgical ward were found to be carrying Haemophilus influenzae. Except for patients with chronic bronchitis, who developed an infection with the same micro-organism, carriage did not predispose patients to postoperative chest infection. Age, heavy smoking, and abdominal surgery increased the likelihood of respiratory infection after operation. H influenzae accounted for 58% of bacterial pathogens isolated from sputum, and most infections occurred within 48 hours of operation. Chemotyping showed that most infections were caused by different strains, and cross infection by H influenzae seemed to be rare. Cefuroxime given during anaesthesia did not prevent postoperative chest infection.
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PMID:Study of postoperative chest infections with particular emphasis on those caused by Haemophilus influenzae. 348 14

Sputum specimens were received for microbiological examination from 110 patients following open heart surgery. The isolation of Haemophilus influenzae occurred significantly more often in those patients who had pre-existing chest disease, but was not associated with postoperative chest problems. There was a significant association between pre-operative heart failure and subsequent severe pulmonary complications.
Anaesthesia 1985 Nov
PMID:Respiratory complications following cardiac surgery. The role of microbiology in its evaluation. 387 2

Seventy-five children not older than 11 years, with secretory otitis media of more than 3 months' duration were randomly divided into two groups prior to myringotomy. One group remained untreated, whereas the other received erythromycin ethylsuccinate (Abboticin) in standard dosage for the last 10 days before surgery. Nasopharyngeal cultures were taken under general anaesthesia, which ensured an uniform mode of sampling. In the erythromycin-treated group the occurrence of Streptococcus pneumoniae (3%) and Branhamella catarrhalis (0%) was significantly lower than in the control group (35% and 32%, respectively); and the frequency of cultures with no pathogen was significantly higher in the treated group. The occurrence of Haemophilus influenzae remained essentially unchanged.
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PMID:The effect of erythromycin on the nasopharyngeal pathogens in children with secretory otitis media. 660 21

Ninety children with acute epiglottitis were admitted from 1971 - 1977. Lateral extended neck radiograph was found to be a quick, safe and reliable way to establish the diagnosis. Out of 79, 77 (97%) had blood cultures yielding Hemophilus influenzae type b. Immediate institution of airway and antibiotics were the mainstay of treatment. All patients in the series survived. For short-term airway management, as in acute epiglottitis, nasotracheal intubation under general anesthesia was found to be the airway of choice.
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PMID:Diagnosis and management of acute epiglottitis -- report of 90 consecutive cases. 696 60

Vertebral biopsies were performed in 28 patients, 17 males and 11 females, because of vertebral body and disc changes between June 1978 and May 1982. In two patients biopsy was performed in two segments. Punctures were done in local and superficial anaesthesia of the vertebral body periosteum during continuous fluoroscopy control using Jamshidi's instrumentation. Aspiration and tissue cylinders were evaluated histologically and bacteriologically. There were no complications among the 8 thoracic and 22 lumbar biopsies. A histologic diagnosis could be established in 22 cases (78.6%): plasmocytoma (n = 2), spontaneous deformation of the spine in osteoporosis (n = 3), Scheuermann's disease (n = 1), specific (n = 2) and nonspecific (n = 14) spondylitis. Demonstration of bacteria was possible in 5 out of the 16 cases of spondylitis (31.25%): in two cases tubercle bacilli were demonstrated and once each salmonella group B, Haemophilus aphrophilus and coagulase-negative staphylococci. Only in 6 cases a diagnosis could not be established from the biopsy material.
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PMID:[Diagnosis of vertebral diseases by vertebral biopsy]. 714 May 65


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