Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0348321 (Haemophilus)
 15,372 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Physicians treated a 37 year old man, who 5 years earlier had a successful vasectomy reversal, with a 24 hour history of intense left testicular pain, rigors, and pain and difficulty in urinating. Prior to these symptoms, he noted a mild, transient urethral discharge. Upon examination, physicians noted a fever of 38.5 degrees Celsius and swelling and tenderness around the left testis extending towards the groin. Pus cells existed in the urine, but no organism was found. While operating on the scrotal sac, physicians observed severe epididymitis which extended to the vasovasostomy site where a firm granuloma existed. The testis itself seemed fine. Blood cultures taken on admission revealed Haemophilus influenzae (non capsulate, biotype II) and ampicillin was administered intravenously. This case's physicians have not heard of any previous reported severe infection of a vasovasostomy site with bacteremia. Generally, granuloma formation after a vasovasostomy is caused by sperm leakage and represents an inflammatory response often resulting in obstruction. This may predispose the site to infection. Haemophilus influenzae rarely causes epididymo-vasitis but perhaps non capsulated strains possess an increased ability to evade host defenses, especially in a vasovasostomy granuloma, a damaged tissue.
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PMID:Epididymo-vasitis associated with previous reversal of sterilisation. 340 94