Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0345904 (liver cancer)
15,188 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein HCC 2985 Sep 986 Mol 778 p53 528 alpha-fetoprotein 357 caspase-3 325 AFP 267 catenin 250 Bcl-2 250 AKT 235 Axin 202 interferon 200 mTOR 199 insulin 189 surface antigen 188 PI3K 186 albumin 179 NMR 160 p21 156 ERK 149 cytokine 141 MAPK 131 vascular endothelial growth factor 126 IFN 123 cyclin D1 122 MRI 121 STAT3 119 E-cadherin 118 cage 113 endoplasmic reticulum 110 TNF 105 CD133 105 ROS 104 TNM 102 PLC 98 VEGF 94 UTR 93 caspase-9 93 JNK 90 histone 90 proliferating cell nuclear antigen 88 PARP 88 aspartate aminotransferase 88 IL-6 87 tumor necrosis factor 85 p38 84 tyrosine kinase 84 serum albumin 83 GSH 82 cytochrome c 82 c-Myc 80 ATP 80 TACE 80 alanine aminotransferase 79 collagen 79 ERK1 78 caspase-8 77 Alpha-fetoprotein 74 ACS 74 PEG 73 annexin V 72 alkaline phosphatase 71 EGFR 70 MMP-9 69 epidermal growth factor receptor 68 CD8 67 c-myc 65 gut 62 AST 58 superoxide dismutase 58 CCK 57 p27 56 ubiquitin 56 survivin 56 prothrombin 55 CD44 55 PTEN 54 matrix metalloproteinase 54 estrogen receptor 53 kit 53 more...

Disease liver cancer 15188 liver cancer 11512 hepatocellular carcinoma 7544 cancer 6595 tumor 4880 HCC 2985 cirrhosis 2024 hepatitis B 1391 Hepatocellular carcinoma 1132 carcinogenesis 801 liver disease 798 hepatitis C 683 tumorigenesis 672 tumor growth 667 carcinoma 667 breast cancer 634 chronic hepatitis 622 lung cancer 563 hepatitis 528 gastric cancer 419 metastases 418 tumor progression 353 colorectal cancer 336 chronic liver disease 295 colon cancer 287 virus infection 274 diabetes 261 viral hepatitis 260 obesity 250 pancreatic cancer 248 liver fibrosis 228 fatty liver 227 prostate cancer 208 leukemia 199 melanoma 173 MCF 169 adenocarcinoma 163 cervical cancer 158 liver metastases 145 esophageal cancer 129 alcoholic fatty liver 118 esophageal cancer 114 hepatoblastoma 108 ovarian cancer 104 bladder cancer 99 infectious diseases 94 lymphoma 93 HIV 92 metabolic syndrome 88 Primary liver cancer 86 Nonalcoholic fatty liver 85 GSH 82 acute hepatitis 81 renal cancer 81 portal hypertension 81 type 2 diabetes 70 Chronic hepatitis B 66 arterial embolization 63 hypertension 61 hemangioma 61 alcoholism 60 adenoma 59 hemochromatosis 58 skin cancer 58 West 57 renal cell carcinoma 56 Hodgkin's disease 54 chronic active hepatitis 54 rectal cancer 53 squamous cell carcinoma 53 aggressiveness 52 Cirrhosis 51 alcohol abuse 50 thyroid cancer 50 primary tumor 49 tumor initiation 48 non-small cell lung cancer 48 Cholangiocarcinoma 47 cardiovascular disease 46 EMT 46 more...

Symptom pain 88 hepatomegaly 53 abdominal pain 41 nausea 34 diarrhea 32 fatigue 30 vomiting 28 anesthesia 22 starvation 20 exhaustion 20 anorexia 19 overweight 17 splenomegaly 16 collapse 12 nausea and vomiting 10 epigastric pain 10 cachexia 9 dyspnea 8 Ill 8 stigma 8 acidity 7 chills 7 weakness 7 abdominal discomfort 7 discomfort 7 discomfort 7 cough 7 right upper quadrant pain 6 headache 6 analgesia 5 chest pain 5 respiratory distress 5 asthenia 4 seizures 4 constipation 4 hemoptysis 4 flushing 3 acute abdominal pain 3 back pain 3 No adverse effect 3 bone pain 3 decreased appetite 3 hypoproteinemia 3 angina 3 cancer pain 3 hepatosplenomegaly 3 shortness of breath 2 Wind 2 Spots 2 ENT 2 masculinization 2 eds 2 hypothermia 2 tense 2 leg edema 2 despair 1 tremor 1 acute stress 1 arthralgia 1 otalgia 1 oliguria 1 pallor 1 abdominal fullness 1 paresis 1 fever of unknown origin 1 regurgitation 1 HSA 1 acute pain 1 halitosis 1 skin damage 1 Chills and fever 1 dark urine 1 decreased skin turgor 1 Neuropathic pain 1 Scratch 1 agitation 1 pleuritic chest pain 1 apathy 1 stomach pain 1 night sweats 1 more...

Drug Sorafenib 161 ROS 104 lysine 77 Lipiodol 75 ROC 40 Monit 40 Adriamycin 36 ADM 35 Portal 27 IL-2 23 caffeine 23 ABC 21 vitamin E 21 Cardiovasc 19 ascorbate 19 Albumin 18 GEO 18 Ethanol 16 Arsenic trioxide 13 HCH 13 IFN-gamma 12 Nexavar 12 NADH 11 ENT 10 MRC 9 Gelfoam 9 ADR 9 CTX 9 MAP 8 lactose 8 Sonazoid 8 Emodin 7 Mutagen 7 Gel 7 CSF 7 Retinoic acid 7 Levovist 7 Gefitinib 7 EE2 7 G418 7 Emodin 7 Leaf 7 CTX 7 Biopolymers 7 DNase I 7 CTX 7 Erlotinib 7 niacin 6 Taxol 6 ALA 6 Entecavir 6 Estrogens 6 Docetaxel 6 Entecavir 6 ZnO 6 citric acid 6 CCL 5 Alliance 5 HCG 5 Dermatol 5 EPA 5 uPA 5 Vitamin A 5 EPI 5 Bifidobacterium 4 Herceptin 4 CAM 4 Nitric Oxide 4 Vitamin E 4 Telbivudine 4 Parkin 4 Fraction 4 CTC 4 Gd-BOPTA 4 PMEA 4 Angiotensin II 4 Gelatin 4 Glutathione 4 Fructose 4 Dakar 4 more...

Enzyme ERK 349 mitogen-activated protein kinase 335 caspase-3 246 alanine aminotransferase 207 luciferase 192 aspartate aminotransferase 146 focal adhesion kinase 144 protein kinase 129 gamma-glutamyl transpeptidase 102 PARP 102 glutathione S-transferase 92 TACE 80 ACS 75 caspase-9 74 MEK 73 alkaline phosphatase 71 superoxide dismutase 69 catalase 61 caspase-8 61 AST 57 AMP-activated protein kinase 51 proteasome 45 cdc2 40 reverse transcriptase 36 AMPK 36 lactate dehydrogenase 34 P-glycoprotein 34 AMPK 33 protein kinase C 31 ATPase 30 glutathione peroxidase 28 phosphatidylinositol 3-kinase 28 RNA polymerase 27 GSK 26 phosphoinositide 3-kinase 25 APC 23 CD13 22 peroxidase 21 topoisomerase 19 urokinase-type plasminogen activator 19 calcineurin 18 acetylcholinesterase 18 glucose-6-phosphatase 17 thymidine kinase 17 NQO1 16 topoisomerase 15 IKK 15 cholinesterase 15 trypsin 15 RNase 15 DNA methyltransferase 14 methionine adenosyltransferase 13 CYP3A4 13 aldehyde dehydrogenase 13 RNase 13 collagenase 12 cathepsin B 11 demethylase 11 aldehyde dehydrogenase 11 MDR 11 aldehyde dehydrogenase 11 aldehyde dehydrogenase 11 aldehyde dehydrogenase 11 MMP 10 glyceraldehyde-3-phosphate dehydrogenase 10 DNA polymerase 10 pyruvate kinase 10 glutathione reductase 10 NADPH oxidase 9 glucose-6-phosphate dehydrogenase 9 transcriptase 9 glyceraldehyde-3-phosphate dehydrogenase 9 granzyme B 9 NADPH oxidase 9 peroxiredoxin 9 NO synthase 9 hexokinase 9 glutaminase 8 pyruvate dehydrogenase 8 acyl-CoA oxidase 8 more...

Compound DNA 1320 Dec 996 Clin 654 oxygen 380 MTT 373 water 360 ethanol 241 glucose 225 iron 165 aflatoxin B1 161 PEG 127 TNF 105 calcium 105 TNM 102 MDA 101 Pac 100 methionine 99 PEG 94 5-FU 93 phosphate 92 galactose 91 lysine 88 sodium 86 GSH 85 GSH 85 TACE 80 ATP 80 tyrosine 78 serine 76 bromide 76 ACS 74 ACS 74 Adriamycin 73 DEN 71 copper 68 iodine 68 cysteine 67 hydrogen 64 acetate 62 arginine 58 zinc 55 MEK 54 nitrogen 52 nitric oxide 51 ADR 48 DDP 48 adenosylmethionine 48 silver 47 selenium 44 His 40 threonine 40 sulfate 39 MMC 39 retinoic acid 39 vinyl 38 alanine 38 leucine 36 TEM 35 urea 34 N-acetylcysteine 34 pyrimidine 33 pyrimidine 33 ethyl acetate 32 Vimentin 31 hyaluronic acid 30 TOF 30 Curcumin 29 salt 29 methanol 28 Insulin 28 PEI 28 ASA 28 PEI 28 Phe 28 pyrene 27 CCl4 26 vitamin D 26 glutamine 26 MTS 26 CO2 25 more...

---