Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0345904 (liver cancer)
15,188 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HCC 2985
Sep 986
Mol 778
p53 528
alpha-fetoprotein 357
caspase-3 325
AFP 267
catenin 250
Bcl-2 250
AKT 235
Axin 202
interferon 200
mTOR 199
insulin 189
surface antigen 188
PI3K 186
albumin 179
NMR 160
p21 156
ERK 149
cytokine 141
MAPK 131
vascular endothelial growth factor 126
IFN 123
cyclin D1 122
MRI 121
STAT3 119
E-cadherin 118
cage 113
endoplasmic reticulum 110
TNF 105
CD133 105
ROS 104
TNM 102
PLC 98
VEGF 94
UTR 93
caspase-9 93
JNK 90
histone 90
more...
Disease
liver cancer 15188
liver cancer 11512
hepatocellular carcinoma 7544
cancer 6595
tumor 4880
HCC 2985
cirrhosis 2024
hepatitis B 1391
Hepatocellular carcinoma 1132
carcinogenesis 801
liver disease 798
hepatitis C 683
tumorigenesis 672
tumor growth 667
carcinoma 667
breast cancer 634
chronic hepatitis 622
lung cancer 563
hepatitis 528
gastric cancer 419
metastases 418
tumor progression 353
colorectal cancer 336
chronic liver disease 295
colon cancer 287
virus infection 274
diabetes 261
viral hepatitis 260
obesity 250
pancreatic cancer 248
liver fibrosis 228
fatty liver 227
prostate cancer 208
leukemia 199
melanoma 173
MCF 169
adenocarcinoma 163
cervical cancer 158
liver metastases 145
esophageal cancer 129
more...
Symptom
pain 88
hepatomegaly 53
abdominal pain 41
nausea 34
diarrhea 32
fatigue 30
vomiting 28
anesthesia 22
starvation 20
exhaustion 20
anorexia 19
overweight 17
splenomegaly 16
collapse 12
epigastric pain 10
nausea and vomiting 10
cachexia 9
stigma 8
dyspnea 8
Ill 8
acidity 7
cough 7
weakness 7
abdominal discomfort 7
discomfort 7
discomfort 7
chills 7
right upper quadrant pain 6
headache 6
respiratory distress 5
analgesia 5
chest pain 5
hemoptysis 4
asthenia 4
seizures 4
constipation 4
hepatosplenomegaly 3
flushing 3
back pain 3
cancer pain 3
more...
Drug
Sorafenib 161
ROS 104
lysine 77
Lipiodol 75
Monit 40
ROC 40
Adriamycin 36
ADM 35
Portal 27
IL-2 23
caffeine 23
ABC 21
vitamin E 21
ascorbate 19
Cardiovasc 19
GEO 18
Albumin 18
Ethanol 16
HCH 13
Arsenic trioxide 13
Nexavar 12
IFN-gamma 12
NADH 11
ENT 10
ADR 9
MRC 9
Gelfoam 9
CTX 9
MAP 8
lactose 8
Sonazoid 8
Emodin 7
Gel 7
CTX 7
Biopolymers 7
DNase I 7
CTX 7
Retinoic acid 7
Levovist 7
Mutagen 7
more...
Enzyme
ERK 349
mitogen-activated protein kinase 335
caspase-3 246
alanine aminotransferase 207
luciferase 192
aspartate aminotransferase 146
focal adhesion kinase 144
protein kinase 129
gamma-glutamyl transpeptidase 102
PARP 102
glutathione S-transferase 92
TACE 80
ACS 75
caspase-9 74
MEK 73
alkaline phosphatase 71
superoxide dismutase 69
catalase 61
caspase-8 61
AST 57
AMP-activated protein kinase 51
proteasome 45
cdc2 40
reverse transcriptase 36
AMPK 36
P-glycoprotein 34
lactate dehydrogenase 34
AMPK 33
protein kinase C 31
ATPase 30
glutathione peroxidase 28
phosphatidylinositol 3-kinase 28
RNA polymerase 27
GSK 26
phosphoinositide 3-kinase 25
APC 23
CD13 22
peroxidase 21
topoisomerase 19
urokinase-type plasminogen activator 19
more...
Compound
DNA 1320
Dec 996
Clin 654
oxygen 380
MTT 373
water 360
ethanol 241
glucose 225
iron 165
aflatoxin B1 161
PEG 127
calcium 105
TNF 105
TNM 102
MDA 101
Pac 100
methionine 99
PEG 94
5-FU 93
phosphate 92
galactose 91
lysine 88
sodium 86
GSH 85
GSH 85
TACE 80
ATP 80
tyrosine 78
bromide 76
serine 76
ACS 74
ACS 74
Adriamycin 73
DEN 71
iodine 68
copper 68
cysteine 67
hydrogen 64
acetate 62
arginine 58
more...