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 28,634 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Graphene oxide suspended in ethanol undergoes reduction as it accepts electrons from UV-irradiated TiO(2) suspensions. The reduction is accompanied by changes in the absorption of the graphene oxide, as the color of the suspension shifts from brown to black. The direct interaction between TiO(2) particles and graphene sheets hinders the collapse of exfoliated sheets of graphene. Solid films cast on a borosilicate glass gap separated by gold-sputtered terminations show an order of magnitude decrease in lateral resistance following reduction with the TiO(2) photocatalyst. The photocatalytic methodology not only provides an on-demand UV-assisted reduction technique but also opens up new ways to obtain photoactive graphene-semiconductor composites.
ACS Nano 2008 Jul
PMID:TiO2-graphene nanocomposites. UV-assisted photocatalytic reduction of graphene oxide. 1920 19

We present the synthesis of a modular delivery system that is composed of two main macromolecular building blocks, dendritic molecular transporter molecules and a polymeric scaffold in a size dimension of 5-10 nm. The conjugated dendritic molecular transporter units proved to be critical for the delivery of the polymer nanoparticle into 3T3 cells and illustrates the dendritic molecular transporter promoted intracellular uptake of polymer particles derived from intramolecular chain collapse processes. In a sequence of modification steps, pyridinyldithio linker was introduced to undergo thiol-disulfide exchange reactions with peptide sequences containing cysteine amino acid units to furnish peptide-nanoparticle conjugates with cleavable disulfide linkers. The intracellular uptake of the nanoparticle conjugates and the delivery of the peptidic cargo were studied via dual labeling of the nanoparticle with Alexa Fluor 568 dye and fluorescein (FITC) markers on the peptide in mammalian cell lines such as NIH 3T3 cells via confocal microscopy. In this work, we have demonstrated the assembly of a novel nanoscopic delivery system in which the conjugated dendritic molecular transporter molecules facilitated the rapid cellular uptake of a nanoparticle-peptide conjugate with up to 25 copies of peptidic cargo to establish new venues for the implementation of protein and oligonucleotide drugs.
ACS Nano 2009 Feb 24
PMID:Molecular dendritic transporter nanoparticle vectors provide efficient intracellular delivery of peptides. 1923 78

Free-standing nanorod arrays of a thermally cross-linked semiconducting triphenylamine were fabricated on conductive ITO/glass substrates via an anodic aluminum oxide (AAO) template-assisted approach. By using a solution wetting method combined with a subsequent thermal imprinting step to fill the nanoporous structure of the template with a cross-linkable triphenylamine derivative, a polymeric replication of the AAO was obtained after thermal curing and selective removal of the template. To obtain well-aligned and free-standing nanorod arrays, aggregation and collapse of the nanorods were prevented by optimizing their aspect ratio and applying a freeze-drying technique to remove the aqueous medium after the etching step. Because of their electrochemical properties and their resistance against organic solvents after curing, these high density nanorod arrays have potential application in organic photovoltaics.
ACS Nano 2009 Jun 23
PMID:Template-assisted fabrication of free-standing nanorod arrays of a hole-conducting cross-linked triphenylamine derivative: toward ordered bulk-heterojunction solar cells. 1945 42

We demonstrated a novel method to produce core/shell composite nanowires (NWs) by self-scrolling carbon nanotubes (CNTs) onto copper NWs via forced-field-based molecular dynamic (MD) simulations. When large diameter CNTs are placed beside the copper NWs, the CNTs approach the NWs, collapse, and self-scroll onto the NWs, resulting in coaxial core/shell composite NWs. It is found that the van der Waals force plays an important role in the formation of the composite NWs. The expected outcome of this novel method is to determine various strategies on how to produce composite NWs. Coaxial core/shell composite NWs represent an important class of nanoscale building blocks with substantial potential for exploring new concepts and functional materials.
ACS Nano 2009 Aug 25
PMID:The core/shell composite nanowires produced by self-scrolling carbon nanotubes onto copper nanowires. 1965 86

Nanopores are ubiquitous in nature and technology, yet relatively little is known about how surface-grafted polymers can affect the interaction forces at the pore. By fabricating Au nanorings on Si substrates, we have constructed a unique experimental platform that allows for direct atomic force microscope (AFM) measurements to be made on polyethylene glycol (PEG) chains locally anchored onto a geometric pore surface. Force measurements show that the PEG gives rise to a steric repulsive barrier that envelops the entire nanoring, signifying polymer brush formation. This is confirmed by a direct imaging of the PEG brush, which reversibly collapses by switching between poor and good solvent conditions to "open" and "close" the pore, respectively. From the view of interaction forces, these results highlight possible functionalities in which polymer brushes may play a role in minimizing fouling/clogging effects in synthetic nanopores and biological nuclear pore complexes (NPCs). By the mechanism of a reversible collapse, this work illustrates how polymer brush-gated nanopores may be used as nonfouling sieves for small molecules and/or solvent-controlled chemical valves that regulate solute traffic.
ACS Nano 2009 Oct 27
PMID:Interaction forces and reversible collapse of a polymer brush-gated nanopore. 1972 98

We report on reversible temperature-triggered swelling transitions in hydrogen-bonded multilayer films of a polycarboxylic acid and stimuli-responsive block copolymer micelles (BCMs). A neutral hydrogen-bonding temperature-responsive diblock copolymer, poly(N-vinylpyrrolidone)-b-poly(N-isopropylacrylamide) (PVPON-b-PNIPAM), was synthesized by macromolecular design via the interchange of xanthates (MADIX). The block copolymer exhibited reversible micellization, forming PNIPAM-core micelles with PVPON coronae in 0.01 M buffer solutions at temperatures higher than 34 degrees C, or in solutions with high salt concentrations (C(NaCl) > 0.4 M) at 20 degrees C. The PVPON-b-PNIPAM BCMs were then assembled with poly(methacrylic acid) (PMAA) at acidic pH and higher temperature using the layer-by-layer (LbL) technique. Within the hydrogen-bonded multilayer, BCMs were stabilized through hydrogen bonding between PVPON and PMAA units and, unlike in solution, did not dissociate into unimers in low-salt solution at T < 34 degrees C. Instead, PVPON-b-PNIPAM BCMs reversibly swelled within film in response to temperature- or salt-concentration variations, reflecting collapse and dissolution of the BCM PNIPAM cores. The capacity of BCM/PMAA films to retain hydrophobic molecules was also dramatically dependent on temperature and/or ionic strength. The characteristic release time of pyrene from a [BCM/PMAA](10) film decreased from 80 to 10 min upon a decrease in temperature from 37 to 20 degrees C. In addition, at 20 degrees C, ionic strength was also capable of controlling the collapse of PNIPAM micellar cores and the subsequent film swelling and pyrene release rate. Incorporation of stimuli-responsive BCM micelles within LbL films opens new opportunities in designing nanoscale films capable of controlling molecular swelling, transport, and diffusion in response to environmental stimuli.
ACS Nano 2009 Nov 24
PMID:Temperature-induced swelling and small molecule release with hydrogen-bonded multilayers of block copolymer micelles. 1979 44

How to lay down nanowires at designated positions is a challenge that undermines the development of nanowire-based devices. We demonstrate that aptamer fibers, which are formed by the self-assembly of multiple aptamers, anchor specifically on the edge of protein patterns. This edge-anchoring effect originates from the biospecific recognition between the aptamer and its target protein. The fractal- shaped aptamer fibers are 1-6 nm high and can be tens of micrometers long. Once these edge-bound fibers have formed, they can serve as scaffolds for further assembly processes. We used these aptamer fibers as templates to fabricate palladium and streptavidin nanowires, which anchored on the pattern edges and never cross over or collapse over each other. The aptamer fiber scaffold provides a solution for fabricating and interfacing nanowires to existing surface patterns.
ACS Nano 2009 Nov 24
PMID:Aptamer fiber anchored on the edge of a protein pattern: a template for nanowire fabrication. 1985 3

Central to porous nanomaterials, with applications spanning catalysts to fuel cells is their (perceived) "fragile" structure, which must remain structurally intact during application lifespan. Here, we use atomistic simulation to explore the mechanical strength of a porous nanomaterial as a first step to characterizing the structural durability of nanoporous materials. In particular, we simulate the mechanical deformation of mesoporous Li-MnO(2) under stress using molecular dynamics simulation. Specifically, such rechargeable Li-ion battery materials suffer volume changes during charge/discharge cycles as Li ions are repeatedly inserted and extracted from the host beta-MnO(2) causing failure as a result of localized stress. However, mesoporous beta-MnO(2) does not suffer structural collapse during cycling. To explain this behavior, we generate a full atomistic model of mesoporous beta-MnO(2) and simulate localized stress associated with charge/discharge cycles. We calculate that mesoporous beta-MnO(2) undergoes a volume expansion of about 16% when Li is fully intercalated, which can only be sustained without structural collapse, if the nanoarchitecture is symmetrically porous, enabling elastic deformation during intercalation. Conversely, we predict that unsymmetric materials, such as nanoparticulate beta-MnO(2), deform plastically, resulting in structural collapse of (Li) storage sites and blocked transport pathways; animations revealing elastic and plastic deformation mechanisms under mechanical load and crystallization of mesoporous Li-MnO(2) are presented at the atomistic level.
ACS Nano 2009 Oct 27
PMID:Simulating mechanical deformation in nanomaterials with application for energy storage in nanoporous architectures. 1985 83

Mesoporous phenol formaldehyde (PF) polymer resin and carbon films are prepared by a solution self-assembly of PF oligomers with amphiphilic triblock copolymers. After thermopolymerization of the PF to cross-link the network, the films show an ordered morphology as determined by X-ray diffraction and grazing incidence small-angle X-ray scattering (GISAXS). Our results show that the amphiphilic triblock copolymer template greatly influences the stability of the final porous mesostructures. The pyrolysis of the two-dimensional (2-D) hexagonal films with p6mm symmetry templated by Pluronic F127 yields a disordered porous structure following the template removal. Conversely, films templated by Pluronic P123 can exhibit well-ordered cylindrical pores after the template removal, but the solution composition range to yield ordered cylindrical mesopores is significantly reduced (nearly 70%) for thin films in comparison to bulk powders. We propose two dominant difficulties in fabricating well-ordered cylindrical mesopores in films: first, the stress from contraction during the pyrolysis can lead to a collapse of the mesostructure if the wall thickness is insufficient, and second, the surface wetting behavior in thin films leads to a small compositional range.
ACS Nano 2010 Jan 26
PMID:Challenges in fabrication of mesoporous carbon films with ordered cylindrical pores via phenolic oligomer self-assembly with triblock copolymers. 2000 Jun 6

Interfacial friction plays a crucial role in the mechanical properties of carbon nanotube based fibers, composites, and devices. Here we use molecular dynamics simulation to investigate the pressure effect on the friction within carbon nanotube bundles. It reveals that the intertube frictional force can be increased by a factor of 1.5-4, depending on tube chirality and radius, when all tubes collapse above a critical pressure and when the bundle remains collapsed with unloading down to atmospheric pressure. Furthermore, the overall cross-sectional area also decreases significantly for the collapsed structure, making the bundle stronger. Our study suggests a new and efficient way to reinforce nanotube fibers, possibly stronger than carbon fibers, for usage at ambient conditions.
ACS Nano 2010 Jan 26
PMID:Enhancement of friction between carbon nanotubes: an efficient strategy to strengthen fibers. 2002 Jul 57


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