Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344329 (collapse)
 28,634 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Prostaglandin derivative SH B 286 (Sulprostone) was administered to 128 induced abortion patients in the 1st trimester of pregnancy on an outpatient basis the evening before curettage was to be performed. 25 mcg of the preparation was injected directly into the uterine wall. There were 5 cases of vomiting, 2 of short term circulatory collapse, and 1 case of abdominal spasms. 7.2% described the contractions as "strong," and 7.8% described the accompanying bleeding as "heavy," compared to menstrual bleeding. Curettage was performed ca. 15 hours after the injection; dilatation could be effected without difficulty. Histological tests showed that the embryo had been expelled in 47.1% of the patients prior to the curettage, with an average expulsion time of ca. 6 hours. No excessive blood loss was reported. The rate of infection was 3.1%.
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PMID:[Outpatient termination of pregnancy via intramural single-shot application of the prostaglandin derivative sh b 286 (sulproston) (author's transl)]. 45 62