Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0344329 (
collapse
)
28,634
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A method was developed to alter surgically the bursa of the bitch to allow sequential observation of the ovary by means of laparoscopy. Adult anesthetized female dogs of three breeds underwent laparoscopic examinations in which each natural bursa slit was lengthened 1.0-1.5 cm using laparoscopic hook scissors in conjunction with electrocautery. The ovary could be effectively and repeatedly exposed for laparoscopic viewing through the lengthened bursa slit. Neither laparoscopic surgery nor frequent routine laparoscopic examinations of the reproductive organs had an effect on subsequent ovarian activity. All dogs subjected to the laparoscopic ovarian exposure technique exhibited estrus behavior, follicle development, ovulation and corpus luteum formation. Preovulatory follicular development was detected as early as 11 days before ovulation with the most rapid follicular maturation occurring two to three days before ovulation. Follicular
collapse
and extensive hemorrhage at the rupture site during ovulation did not occur. Release of the cumulus mass from a vesicular follicle was observed in one bitch. The cumulative mass adhered to the follicular wall for an indefinite time following ovulation. The structural size of the bitch corpus luteum was maximal four to eight days following ovulation. Corpora lutea remained visible on the ovarian surface for 16 weeks. No differences in cyclic ovarian morphology were observed among the three breeds of dogs studied.
Anat
Rec
1977 Nov
PMID:Laparoscopic exposure and sequential observation of the ovary of the cycling bitch. 14 45
An eight-year-old male Yorkshire terrier which had had a cough for two years was presented and a diagnosis of tracheal
collapse
was made after examination with a bronchoscope. It was decided to try to correct the tracheal defect by plication. Two weeks after the operation the dog was examined under general anaesthesia. Although traction had exposed a part of the thoracic trachea it was not sufficient in this case to achieve a complete repair. In view of a grave prognosis, the dog was destroyed.
Vet
Rec
1977 Jul 16
PMID:A case of tracheal collapse in the dog. 32 44
The philtrum point VG 26 (Jen Chung) was needled in 69 cases of respiratory depression or apnoea in dogs and cats during induction or maintenance of general anaesthesia. Respiration was restored to normal or near normal rates within 10 to 30 seconds of insertion of the needle in all the cases. In seven cases of anaesthetic apnoea with concurrent cardiac arrest and absence of vital signs, the revival rate was 43 per cent. Those which recovered required four to 10 minutes of acupuncture stimulation. In eight cases of
collapse
due to other causes, the revival rate was 25 per cent. The cases included five sheep in shock following liver biopsy, two cases of haemorrhagic shock (dog, cat) and one terminal
collapse
in chronic congestive heart failure (dog).
Vet
Rec
1979 Sep 22
PMID:Respiratory and cardiac arrest under general anaesthesia: treatment by acupuncture of the nasal philtrum. 51 10
Following sudden exposure to extreme cold, a group of 15-week-old pigs exhibited strange nervous signs which included arching the back, a high stepping gait, violent tremors of the whole body and screaming. The animals lowered themselves and once sitting, the tremors and screaming stopped. But if forced to rise, these signs recurred. When the pigs returned to a warmer environment, they rapidly recovered. An acute clinical myopathy caused by a marginal vitamin E deficiency was suspected. Other stress-induced factors, such as circulatory
collapse
caused by movement from a warm to a cold environment, were also thought to have contributed towards the myopathy.
Vet
Rec
1979 Sep 22
PMID:Suspected acute myopathy of pigs. 51 11
An acute respiratory distress syndrome in 10 adult dogs was usually preceded by vomiting, anorexia and lethargy followed, after a short interval, by dyspnoea. The dyspnoea became increasingly severe, despite oxygen therapy, and cyanotic respiratory failure ensued. All 10 dogs died or were killed after illnesses lasting between one and eight days. Necropsies revealed pulmonary congestion, oedema,
collapse
and haemorrhage with loss of alveolar epithelial cells. Early alveolar fibrosis was also found. Paraquat was identified in post mortem samples from four of the 10 dogs.
Vet
Rec
1977 Apr 02
PMID:Acute respiratory distress in the dog associated with paraquat poisoning. 86 Mar 82
Cases of a diarrhoeic syndrome characterised by acute
collapse
were seen in single-suckled beef calves on hill farms during a three year period. The association between the occurrence of this syndrome, which we have termed the "collapse syndrome", and various epidemiological parameters, is investigated and discussed.
Vet
Rec
1975 Nov 08
PMID:The epidemiology of the "collapse syndrome" in suckled calves. 119 86
A total of 351 single-suckled beef calves were blood sampled at twice-weekly intervals for the first two and a half weeks of life. Twenty three of them died, 13 of a syndrome characterised by acute
collapse
and 10 of diarrhoea which had persisted for several days before death. Those which died acutely showed a sudden terminal rise in blood levels of potassium, magnesium, inorganic phosphate and total protein. Those which died after several days of diarrhoea showed a more gradual increase in blood chloride and urea concentrations and in packed cell volume values. It is suggested that these changes indicate a difference in the pathogenesis of the two situations. Calves which died had lower blood glucose levels before the onset of clinical signs than those which survived. It is suggested that this may have been a contributory factor in their mortality.
Vet
Rec
1975 Nov 29
PMID:Biochemical studies of the "collapse syndrome" in suckled calves. 121 27
The nuclear envelope of polytene nuclei of salivary glands of Drosophila melanogaster displays modifications consisting of nuclear envelope invaginations (NEI) and evaginations (NEE). Ultrastructural analyses combined with three-dimensional reconstruction and cytochemistry show that NEI are bounded by a single membrane and that they may arise as invaginations of the inner nuclear membrane. NEI extend deeply into the nucleus. The lumens of NEI may
collapse
resulting in membranous sheets which may combine with those arising from adjacent NEI to form intranuclear structures resembling annulate lamellae. All NEI are associated with NEE. In contrast to NEI, NEE are enclosed in a double membrane morphologically identical to the nuclear envelope. While NEI and NEE share wheat germ agglutinin binding properties with the nuclear envelope, they differ in their ability to localize lanthanum. Pore annuli of NEI display complete lack of lanthanum binding, while those of NEE exhibit minor deposition of this cation. In contrast, pore annuli of the nuclear envelope are specifically and significantly decorated by lanthanum. A conceptual model based on the results obtained suggests that NEI are formed by invaginations of the inner nuclear membrane, together with accompanying modifications of pore complexes.
Anat
Rec
1992 Sep
PMID:Nuclear membrane modifications in polytene nuclei of Drosophila melanogaster: serial reconstruction and cytochemistry. 141 94
The hyaline layer (HL) is a multilayered extracellular matrix (ECM) that coats the external surfaces of sea urchin and starfish embryos. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. Ultrastructural studies of chemically fixed embryos have shown the HL to consist of two to four sublayers. However, since chemical fixatives may cause
collapse
and alter the positions and antigenicity of the extracellular components, fixation methods that exclude chemicals may reveal a picture of the HL closer to what is present in vivo. Freeze substitution, a fixation method whereby tissues are rapidly frozen and dehydrated at low temperatures, has proved useful for fixing material rich in ECM. In this study, embryos of the starfish Pisaster ochraceus were fixed for microscopy using freeze substitution and three chemical methods in order to determine, as accurately as possible, the structure of the HL. Embryos appear to be best preserved by freeze substitution and demonstrate a HL consisting of at least six distinct sublayers. Based on staining with anionic dyes, most sublayers appear to contain glycosaminoglycans. Freeze substituted embryos, which were also stained with monoclonal antibodies raised against their ECM, revealed that some molecules are common to all six sublayers, whereas other molecules may be restricted to specific sublayers. This suggests that each sublayer could have a different function. Additional evidence suggests that microvillus associated bodies, present in other marine invertebrate embryos, may anchor the asteroid HL to the cell surface microvilli.
Anat
Rec
1991 Sep
PMID:Ultrastructural study of the hyaline layer of the starfish embryo, Pisaster ochraceus. 172 6
We explored the possibility of synergism between a pure-tone stimulus and gentamicin in causing cochlear injury by analyzing hair cell loss. Guinea pigs receiving daily injections of gentamicin (200 mg/kg body wt.) for 1 week were exposed to a 2 kHz tone (95 dB SPL, 2 hours daily). Surface preparations of the spiral organ were studied by phase contrast microscopy, and the extent of hair cell loss in the entire organ of Corti was recorded in cytocochleograms. Gentamicin by itself was slightly ototoxic, damaging the innermost row of outer hair cells, whereas exposure to sound alone caused no hair cell loss. Combined antibiotic and acoustic exposure produced extensive cochlear damage. A few animals showed massive hair cell degeneration and
collapse
of the organ of Corti, except in the apical turn. The site of damage was possibly determined by the frequency of the sound stimulus. Thus, an intermittent tonal stimulus such as that used in the present experiment can be harmless by itself, but causes injury to cochlear hair cells in guinea pigs when administered in combination with gentamicin.
Anat
Rec
1991 May
PMID:Potentiation of cochlear hair cell loss by acoustic stimulus and gentamicin in the guinea pig. 206 25
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