Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
B1F3 10.1
tcag7.1213 10.1
AIM1L 10.1
P450DB1 9.1
G-protein coupled receptor 35 9.1
POM121L2 9.1
ZNF568 9.1
KCNG4 8.6
SNSR1 8.6
regulator of G-protein signaling 9 8.1
levocabastine-sensitive neurotensin receptor 8.1
MOR-1 8.1
G-protein-coupled receptor kinase 3 7.8
CLCC1 7.8
Mu opioid receptor 7.7
Neuropeptide FF 7.6
G protein-coupled receptor 10 7.6
OPRL1 7.4
NPFF 7.4
Exp6 7.3
TAFA4 7.3
Prepronociceptin 7.3
C-SAA 7.3
mu opioid receptor 7.2
DOR1 7.1
PIPP 7.1
opioid receptor mu 7.1
BUP 7.0
HSAN II 7.0
KCNJ6 6.9
OPRM1 6.9
nociceptin receptor 6.9
NPFF2 6.8
ZNF165 6.8
transient receptor potential cation channel, subfamily V, member 1 6.8
ORL1 6.8
OFQ 6.8
opioid receptor 6.8
POD1 6.7
CRIP1a 6.7
prepronociceptin 6.7
protein phosphatase 3 6.7
TAOK3 6.7
ERAS 6.6
PDYN 6.6
delta opioid receptor 6.6
WDR33 6.6
RGSZ1 6.6
NPFF1 6.5
RGS17 6.5
OR1A1 6.4
G protein-coupled receptor 35 6.4
kappa opioid receptor 6.4
BNF1 6.3
KOR 6.3
PPID 6.3
ASA 6.3
UDP-glucuronosyltransferase 2B7 6.3
epithelial mitogen 6.2
RGS9 6.2
MOR1 6.1
CHAR 6.1
TFL 6.1
leu5 6.1
NRM 6.1
NKTR 6.1
casein kinase 1 epsilon 6.1
GCPS 6.1
GIRK3 6.0
Leu5 6.0
PAG 6.0
PIG-T 6.0
Nav1.7 6.0
KOP 5.9
opiorphin 5.9
LVV-hemorphin-7 5.8
ghrelin precursor 5.8
TMEM97 5.8
PRN 5.8
PLEK 5.7
more...
Disease
Tonsillar fossa 10.1
Acute sciatica 10.1
Hemoglobin SE disease 9.1
Basal pneumonia 9.1
cerebellotrigeminal and focal dermal dysplasia 9.1
Facial neuralgia 9.1
female genital disease 8.6
Arthrosis deformans 8.6
immobility syndrome 8.6
Uterine pain 7.8
Cerebellar astrocytoma 7.8
Epidural abscess 7.7
Postoperative ileus 7.6
Loin pain hematuria syndrome 7.6
anal spasm 7.6
Vagal bradycardia 7.6
Chorea gravidarum 7.3
Lumbosacral radiculopathy 7.3
osteolytic sarcoma 7.1
thoracic disc prolapse 7.0
Ectopic parathyroid adenoma 7.0
Impacted teeth 6.9
physical dependence 6.7
CHAR 6.7
Bowel dysfunction 6.6
Opiates 6.6
HIV neuropathy 6.6
Ankle osteoarthritis 6.6
Complicated appendicitis 6.6
Transient hypertension 6.5
Acute glaucoma 6.4
Laryngeal obstruction 6.4
head or neck cancer 6.4
Ehlers-Danlos syndrome type III 6.4
phantom limb pain 6.4
Flail chest 6.4
Needle phobia 6.3
Burn shock 6.3
Renal artery occlusion 6.3
Fear of childbirth 6.3
chronic pain 6.2
Mouse Lymphoma 6.2
Intervertebral disc calcification 6.1
Fear of pain 6.1
refractory cancer 6.1
Biliary dyskinesia 6.1
catalepsy 6.1
Neuromuscular blockade 6.1
Autotomy 6.0
Phrenic nerve palsy 6.0
Erosive osteoarthritis 5.9
narcotic dependence 5.8
oral herpes 5.8
Retained placenta 5.8
Trichostasis spinulosa 5.7
ophthalmic migraine 5.7
nerve sheath neoplasm 5.7
Cardiorespiratory failure 5.7
Frey 5.7
PCA 5.7
Reflex bradycardia 5.7
regional pain syndrome 5.7
Perforated peptic ulcer 5.7
Infective dermatitis 5.7
Peroneal nerve palsy 5.7
Morphine dependence 5.6
Solitary plasmacytoma of bone 5.6
Ochronotic arthropathy 5.6
Fear of cancer 5.6
chemical hypersensitivity 5.5
Septic abortion 5.4
pruritus 5.4
postherpetic neuralgia 5.4
Neuromuscular blockade 5.4
unable to remember 5.3
Lumbar disc herniation 5.3
Irukandji syndrome 5.3
Intractable epilepsy 5.3
Pulmonary tumor embolism 5.3
bone cancer 5.3
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Symptom
Obstetric pain 10.1
analgesia 10.1
Central abdominal pain 10.1
Ureteric colic 9.1
Postpartum headache 9.1
Sharp pain 8.8
Postoperative pain 8.6
Intercostal neuralgia 8.6
postpartum pain 8.4
breakthrough pain 8.3
Labor pain 8.3
Postoperative nausea 8.3
Transient paresthesia 8.1
Post dural puncture headache 8.1
Grimace 8.1
Incisional pain 7.8
Pain during injection 7.8
peritoneal pain 7.8
Metastatic bone pain 7.8
Perineal pain 7.8
acute pain 7.7
Sedation 7.6
cervical spasm 7.6
Chest wall pain 7.6
cancer pain 7.4
Somatic pain 7.3
Diffuse pain 7.3
sacralgia 7.3
PAIN 7.2
Postoperative nausea and vomiting 7.2
Chronic intractable pain 7.1
Wound pain 7.1
hypalgesia 7.0
Postoperative vomiting 6.9
Chronic chest pain 6.8
Injection site pain 6.8
Inflammatory pain 6.7
bradypnea 6.7
Intractable pain 6.6
Severe pain 6.6
Visceral pain 6.6
Gastrointestinal discomfort 6.6
Post-lumbar puncture headache 6.6
Procedural pain 6.6
Deep pain 6.6
Central pain 6.5
inflammation of the tonsils 6.4
Early complication 6.4
Neuromuscular weakness 6.4
difficulty with urination 6.4
Hyposensitivity 6.3
clammy skin 6.3
Pain at rest 6.3
Atypical facial pain 6.3
Mild pain 6.3
dental pain 6.3
Neurogenic pain 6.2
skin pain 6.2
anesthesia 6.2
nausea and vomiting 6.2
Fetal bradycardia 6.1
musculoskeletal chest pain 6.1
Chest discomfort 6.1
side pain 6.0
Stinging 6.0
No pain 6.0
pain 5.9
GI pain 5.9
Burning pain 5.9
mouth pain 5.8
Thoracic pain 5.8
nerve root irritation 5.7
renal colic 5.7
Radicular pain 5.7
renal pain 5.7
muscular incoordination 5.6
Generalized pruritus 5.6
Lower abdominal pain 5.6
stump pain 5.6
impaired motor coordination 5.6
more...
Drug
Pethilorfan 10.1
Icotidine 10.1
Tonazocine mesylate 9.1
Trimeperidine 9.1
Naropin 9.1
Ultiva 8.8
Pentamorphone 8.8
Nesacaine 8.7
Fentanyl citrate 8.7
Remifentanyl 8.7
Nubain 8.6
Pemedolac 8.6
C16H15NO4 8.6
Palladone 8.6
Detomidine hydrochloride 8.6
Chirocaine 8.6
Chirocaine 8.6
Dilaudid 8.4
Dolobid 8.3
Nubain 8.3
Duranest 8.1
Deracoxib 8.1
Percamin 8.1
Nesacaine 8.1
Vivitrex 8.1
Saridon 8.1
Bupivacaine 8.1
Flurbiprofen axetil 8.0
Oxycontin 8.0
Tapentadol 8.0
Alvimopan 8.0
Ketorolac 8.0
Butorphanol 7.9
Fentanyl 7.9
Amethocaine 7.9
Tramadol hydrochloride 7.9
Emla 7.8
Emla 7.8
Morphine hydrochloride 7.8
Flupirtine maleate 7.8
Demerol 7.8
Percocet 7.7
C2H5Cl 7.7
Demerol 7.7
Parecoxib sodium 7.7
Methadone hydrochloride 7.7
Medetomidine 7.6
Bromfenac sodium 7.6
Ziconotide 7.6
Oxilorphan 7.6
Marcaine 7.5
Tramal 7.5
Naloxone HCl 7.4
Butorphanol tartrate 7.4
Anexate 7.4
Vedaprofen 7.3
Parecoxib 7.3
Selectol 7.3
Buprenorphine hydrochloride 7.3
Emla 7.3
Morphine sulfate 7.2
Hydrocodone bitartrate 7.1
Zomepirac sodium 7.1
Percodan 7.1
mepivacaine hydrochloride 7.1
Lornoxicam 7.0
Subutex 7.0
Fluproquazone 7.0
Carbocaine 7.0
Citanest 7.0
Citanest 7.0
Feldene 6.9
Ketorolac tromethamine 6.9
Hypnomidate 6.9
Naltrexone hydrochloride 6.9
Codeine 6.8
Limaprost 6.8
Radicut 6.8
Aquavan 6.8
Codeine 6.8
more...
Enzyme
kyotorphin synthetase 7.8
morphine 6-dehydrogenase 6.8
aspirin esterase 6.2
monoacylglycerol lipase 4.8
proprotein convertase 1 4.6
BIS 4.4
C1 esterase 4.1
CPM 4.1
SRR 4.1
IOR 3.9
PPH 3.8
3alpha-hydroxysteroid dehydrogenase 3.6
3-oxoacid CoA-transferase 3.5
glutaryl-CoA dehydrogenase 3.4
Lys4 3.3
arginine decarboxylase 3.1
SpeB 3.0
CPN 3.0
tryptophan hydroxylase 2.9
arginine decarboxylase 2.9
prostaglandin synthetase 2.8
VIP1 2.7
CAO 2.7
dopamine beta-hydroxylase 2.7
proteinase A 2.6
meprin 2.6
histamine N-methyltransferase 2.6
GRK5 2.6
homogentisate 1,2-dioxygenase 2.6
hyaluronidase 2.6
MTD 2.5
carboxypeptidase E 2.5
SCS 2.5
AAE 2.4
GTP cyclohydrolase I 2.4
phosphatidylethanolamine N-methyltransferase 2.3
oxytocinase 2.3
endo-N 2.3
NCP 2.2
carboxypeptidase A 2.2
MAP 2.2
ADH 2.2
cathepsin S 2.2
FAST 2.2
hyaluronidase 2.1
proteinase A 2.1
PRE 2.0
GRK2 2.0
CD13 1.9
botulinum neurotoxin 1.8
endothelin-converting enzyme 1.8
cGMP phosphodiesterase 1.8
FPS 1.7
guanylate cyclase 1.7
soluble epoxide hydrolase 1.6
PCP 1.6
catechol O-methyltransferase 1.5
MCS 1.5
TAT 1.5
PMT 1.5
GABA transaminase 1.5
chymopapain 1.5
CD10 1.5
methionine synthase 1.4
dipeptidyl peptidase IV 1.4
chymopapain 1.4
12-lipoxygenase 1.4
P-glycoprotein 1.4
BMT 1.4
methionine synthase 1.3
adenosine kinase 1.3
caspase-6 1.2
DMT 1.2
cholinesterase 1.2
DAT 1.2
caspase-6 1.2
apyrase 1.1
CPT 1.1
5alpha-reductase 1.1
5alpha-reductase 1.1
more...
Compound
Oxymorphonazine 10.1
Ionsys 10.1
Psychotridine 10.1
Kentsin 9.6
Pimprinine 9.1
2-Amino-5-phosphopentanoic acid 9.1
Mesembrine 8.8
Chloroprocaine 8.7
C6H12O 8.6
Dihydrokawain 8.6
Psyquil 8.6
ribosylimidazoleacetate 8.6
Hodgkinsine 8.6
Oxidized dithiothreitol 8.6
Alodan 8.6
Ropivacaine 8.5
Levobupivacaine 8.5
Remifentanil 8.4
Sufentanil 8.4
8-azabicyclo[3.2.1]octan-3-ol 8.3
(+)-Borneol 8.3
Meperidine 8.2
Nalbuphine 8.2
Etidocaine 8.2
Fendosal 8.1
1-piperazinecarboxylic acid 8.1
8-azabicyclo[3.2.1]octan-3-ol 8.1
Dezocine 8.1
MPTA 8.1
Bupivacaine 8.1
Ketorolac 8.1
8-azabicyclo[3.2.1]octan-3-ol 8.0
Dihydrocodeine 8.0
Dilaudid 7.9
Butorphanol 7.8
1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 7.8
Kyotorphin 7.8
Oxymorphone 7.7
Tramadol 7.7
Alfentanil 7.7
Mepivacaine 7.7
Methoxyflurane 7.6
Ketobemidone 7.6
Dihydromorphine 7.6
CDBA 7.6
Oxycodone 7.5
Morphine 7.5
Buprenorphine 7.4
Dexmedetomidine 7.4
Morphiceptin 7.4
HP 549 7.3
Methadone hydrochloride 7.3
Pentazocine 7.3
Hydrocodone 7.3
Pentazocine 7.2
Oxycodone hydrochloride 7.1
Heroin hydrochloride 7.1
Naloxonazine 7.1
Morphine sulfate 7.1
Lappaconitine 7.0
New Methylene Blue 7.0
Nalorphine 7.0
D-Phenylalanine 7.0
Carprofen 6.9
Prilocaine 6.9
Diprenorphine 6.9
Anexate 6.9
Azaperone 6.9
Droperidol 6.8
Levomepromazine 6.8
L-365260 6.8
Curacin A 6.8
Ketamine 6.8
DAMGO 6.8
Codeine 6.8
Hydromorphone 6.7
Levorphanol 6.7
Resiniferatoxin 6.7
HM-4 6.7
Tifluadom 6.7
more...