Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0344307 (
analgesia
)
28,200
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1789
opioid receptor
1096
ASA
450
beta-endorphin
444
Mol
249
substance P
236
GABA
229
PCA
221
She
219
oxytocin
209
dynorphin
178
mu opioid receptor
159
CO2
155
NMDA receptor
155
cholecystokinin
138
5-hydroxytryptamine
125
OFQ
122
CB1
116
cannabinoid receptor
104
calcitonin
102
COX-2
100
MRI
99
T10
96
calcium channel
95
Pol
93
cytokine
91
ACTH
88
insulin
85
Leu5
81
cyclooxygenase
79
CSF
78
neurotensin
78
kappa opioid receptor
73
delta opioid receptor
73
TRPV1
71
hemoglobin
68
T12
68
cage
66
Met
66
gut
65
vasopressin
64
Met-enkephalin
62
prolactin
62
nitric oxide synthase
61
CB2
60
CCK
60
bradykinin
59
neutral endopeptidase
58
rat)
57
reserved
57
Rec
57
cyclooxygenase-2
56
ANOVA
56
IL-6
56
ATP
55
somatostatin
54
Gen
53
THC
52
fatty acid amide hydrolase
50
TNF
49
DBA
48
dilute
48
arrestin
46
5-HT1A
46
PAG
45
nicotinic acetylcholine receptor
44
OPRM1
44
COX-1
44
Leu-enkephalin
44
tumor necrosis factor
43
ORL1
41
corticotropin-releasing factor
41
axonal
40
albumin
38
c-fos
38
AMP
38
MIF
37
HT3
37
nerve growth factor
36
TLR4
36
more...
Disease
depression
1651
chronic pain
1307
cancer
913
pruritus
559
cold
478
addiction
297
hypertension
286
tumor
239
PCA
221
osteoarthritis
191
physical dependence
152
diabetes
151
amnesia
149
delirium
142
catalepsy
141
ischemia
131
Frey
123
arthritis
120
stroke
119
Thoracic
118
Best
114
neuropathy
113
SEM
113
fits
111
hernia
111
ileus
110
pneumothorax
108
obesity
108
metastases
103
sepsis
99
abortion
96
sepsis
92
migraine
86
sickle cell disease
85
pneumonia
84
breast cancer
83
rheumatoid arthritis
82
uterus
81
myocardial infarction
77
inguinal hernia
76
fibromyalgia
75
epilepsy
71
cognitive impairment
69
myocardial ischemia
67
deep vein thrombosis
66
aggression
64
confusion
64
preeclampsia
63
carcinoma
61
scoliosis
60
renal failure
60
respiratory failure
59
postherpetic neuralgia
58
gallstones
55
osteoporosis
55
West
52
pertussis
52
regional pain syndrome
50
THC
49
heart disease
48
hallucinations
48
drug addiction
48
compartment syndrome
48
DBA
48
anemia
47
pancreatitis
47
diabetic neuropathy
46
peripheral neuropathy
46
coma
46
coagulopathy
45
bone metastases
45
acute pancreatitis
44
prolapse
44
asthma
44
Parkinson's disease
44
chronic obstructive pulmonary disease
42
mental illness
42
phantom limb pain
41
emphysema
41
drug abuse
41
more...
Symptom
analgesia
28200
pain
14242
anesthesia
6982
nausea
868
acute pain
727
vomiting
695
nausea and vomiting
606
cancer pain
461
headache
440
Postoperative pain
382
discomfort
356
discomfort
345
hypothermia
296
sleepiness
241
Sedation
226
constipation
225
seizures
205
cough
197
agitation
166
back pain
157
abdominal pain
149
weakness
148
dizziness
142
breakthrough pain
120
low back pain
103
paresthesia
88
diarrhea
88
fatigue
86
dental pain
83
numbness
78
ataxia
75
hypercapnia
71
distraction
68
functional recovery
61
respiratory distress
57
Neuropathic pain
56
dyspnea
56
chest pain
52
bone pain
50
arthralgia
45
acute stress
44
tremor
44
paresis
43
erythema
43
Wind
40
spasm
40
collapse
39
renal colic
38
spasticity
37
colic
35
angina
34
Postoperative nausea and vomiting
34
pelvic pain
32
neuralgia
32
myalgia
30
shoulder pain
28
insomnia
28
anorexia
26
facial pain
26
sore throat
25
tachypnea
24
muscle rigidity
23
orofacial pain
22
neck pain
21
hypalgesia
20
chronic back pain
20
knee pain
19
epigastric pain
19
leg pain
19
bradypnea
18
limb pain
16
postpartum pain
16
Grimace
16
pallor
16
cyanosis
15
exhaustion
15
hyperesthesia
14
ENT
14
Severe pain
14
myoclonus
14
more...
Drug
Fentanyl
277
Bupivacaine
193
Clonidine
126
Cardiovasc
90
Propofol
89
CSF
81
Monit
71
Ketorolac
66
caffeine
63
Dermatol
43
9-THC
40
Butorphanol
38
Codeine
37
MAP
37
Medetomidine
35
ICI
35
nitroglycerin
34
Codeine
33
lysine
32
Xylocaine
31
DHT
30
DHT
30
Nephron
27
Gabapentin
26
Tapentadol
26
Atropine
25
ENT
20
Ringer's solution
17
Marcaine
17
Histamine
16
Tramal
16
Indomethacin
16
Morphine sulfate
15
Ziconotide
15
Ethanol
15
Xylocaine
14
Pregabalin
14
Demerol
13
EE2
13
Diclofenac sodium
13
Ketorolac tromethamine
12
Xylocaine
11
MgSO4
11
Meconium
11
Voltaren
11
L-tyrosine
11
PCP
10
Tramadol hydrochloride
10
CPM
10
Subutex
9
Nubain
9
Proglumide
9
Leaf
9
FLP
9
Scopolamine
9
Phentolamine
9
CaCl2
8
CaCl2
8
CTX
8
Naropin
8
Alvimopan
8
CaCl2
8
Misoprostol
8
Parecoxib
8
Portal
8
Thiopentone
8
Demerol
8
Fentanyl citrate
8
Morphine hydrochloride
7
Atipamezole
7
lactose
7
Nimesulide
7
Gel
7
IL-2
7
CDP
7
Dipyrone
7
IL-1ra
7
DMI
7
Domperidone
7
THA
7
more...
Enzyme
mitogen-activated protein kinase
75
protein kinase C
66
protein kinase
53
ERK
53
acetylcholinesterase
43
peroxidase
40
ACS
34
P-glycoprotein
31
adenylate cyclase
30
MAP
30
cholinesterase
26
creatine kinase
24
CD10
24
guanylate cyclase
24
hyaluronidase
24
hyaluronidase
24
renin
22
alanine aminotransferase
21
NO synthase
19
BIS
18
tyrosine hydroxylase
17
phosphodiesterase
17
monoacylglycerol lipase
17
monoamine oxidase
17
aspartate aminotransferase
15
phospholipase C
15
ACE
14
lipase
13
CD13
12
tryptophan hydroxylase
12
CYP3A4
11
prostaglandin synthetase
11
lipoxygenase
10
PCP
10
alkaline phosphatase
10
CPM
10
thromboplastin
10
phospholipase A2
9
trypsin
9
MEK
9
alcohol dehydrogenase
9
ADH
9
luciferase
8
thrombin
8
dopamine beta-hydroxylase
8
caspase-3
8
lipoprotein lipase
7
PRE
7
NADPH-diaphorase
7
GRK5
6
soluble epoxide hydrolase
6
lactate dehydrogenase
6
superoxide dismutase
6
CPT
6
TAT
6
botulinum neurotoxin
6
tissue plasminogen activator
6
BMT
6
CPT
6
focal adhesion kinase
6
CPT
6
collagenase
5
demethylase
5
AST
5
NOS
5
APC
5
phosphatidylinositol 3-kinase
5
ATPase
5
SCS
5
catalase
5
CaMKII
4
MIP
4
gamma-glutamyl transpeptidase
4
glutamate decarboxylase
4
arginine decarboxylase
4
arginine decarboxylase
4
carboxypeptidase A
4
calcineurin
4
dipeptidyl peptidase IV
4
choline acetyltransferase
4
more...
Compound
Dec
1930
Clin
1786
oxygen
897
Morphine
799
water
660
ASA
485
sodium
378
Naloxone
333
glucose
330
calcium
300
CO2
274
sulfate
260
acetic acid
250
5-HT
243
Gly
243
tyrosine
242
Phe
235
Ketamine
231
GABA
230
GABA
230
N2O
217
glutamate
211
noradrenaline
191
Bupivacaine
188
arginine
173
APAP
170
potassium
146
leucine
145
ethanol
143
NMDA
140
DAMGO
137
HCl
131
Dexmedetomidine
130
Buprenorphine
128
Tramadol
127
methionine
125
NH2
120
Lidocaine
119
nitric oxide
109
Remifentanil
107
T10
96
D-Ala
95
Meperidine
91
Propofol
89
galactose
88
ACTH
87
cAMP
80
Ropivacaine
79
Naltrexone
76
His
73
lysine
72
gamma-aminobutyric acid
70
threonine
70
phosphate
66
caffeine
64
nitrogen
64
alanine
63
Ketorolac
63
Midazolam
63
creatinine
57
Adrenal
57
ATP
55
Optimal
53
Sufentanil
52
DNA
52
salt
50
DBA
50
TNF
49
acetate
49
DBA
48
DBA
48
Diazepam
47
formaldehyde
45
tryptophan
45
PAG
45
Methadone
44
Capsaicin
44
sodium chloride
43
Alfentanil
42
Oxycodone
42
more...