Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Immunological indexes have been studied in 22 patients during planned herniotomy and in 52 healthy donors. The study group comprised 12 patients operated on under local anesthesia in combination with electroacupuncture analgesia (EAPA). Premedication was not performed, narcotic analgesics, neuroleptics and antihistamine agents were also excluded. The control group consisted of 10 patients operated on under local anesthesia after premedication with promedol. Analgesia in the postoperative period was performed using chEHC-2 apparatus in the study group and using narcotic analgesics in the control group. Most indexes characterizing the initial immune status were decreased in both groups, as compared to those observed in healthy donors. A pronounced immunomodulating effect of EAPA on immunoregulatory subpopulations of T-lymphocyte helpers/inducers (Tmu) and suppressors/killers (T gamma) was noted. EAPA did not affect optimal relations between immunoregulatory subpopulations, which was confirmed by immunoregulatory index value, and prevented inhibition of functional lymphocyte activity in blasttransformation reaction to mitogen (PHA).
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PMID:[Electroacupuncture in the prevention of the immunosuppressive action of surgical stress]. 280 48