Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pectus excavatum is the common congenital chest wall deformity in children, and Nuss procedure is the conventional surgical treatment for this disease. Nuss procedure is superior to Ravitch correction for it is less harmful in terms of the surgical technique. However, Nuss procedure is associated with severe postoperative pain, thus adequate postoperative analgesia is important. In this review, factors that influence the postoperative pain after Nuss procedure, the pain managements, the related complications and the side effects of drugs are discussed.
Zhejiang Da Xue Xue Bao Yi Xue Ban 2013 Mar
PMID:[Research progress on postoperative analgesia for pectus excavatum in pediatric patients after Nuss procedure]. 2358 12

With its powerful ability to monitoring and support of organs, the survival rate of critically ill patients has been improved significantly by critical care medicine. Critical ill patients centralized in ICU accepted the treatments given by multidisciplinary team as a mode have played a very important role, especially during the rescue of victims in public health emergencies and natural disasters. Changings of the measures of monitoring and support are always along with the development of the critical care medicine. Fluid therapy is the most core measures in ICU, but there is a significant contradiction between positive fluid therapy and patient's impaired organ compensatory ability. The premise of appropriate fluid therapy is continuous and accurate evaluation of the hemodynamic status of critical ill patients. The variation of peak velocity of common carotid artery measured by bedside ultrasound can estimate the volume status of the SICU patients accurately. This method has high feasibility and accuracy and easy to be handled by the residents of ICU. The non-C. difficile associated nosocomial diarrhea even fatal enteritis in ICU can be caused by Klebsiella oxytoca and Clostridium perfringens. Although this kind of incidence occurs in a relatively low rate, it always associates with severe diseases and poor outcome. Analgesia and sedation had become routine measures in ICU. There is still great controversy in some of the sedation protocol, such as sedation level and wake up daily. More and more evidence-based data suggested taking appropriate sedation targeting to individuals, and the protocol should be integrated with the dealing of pain, anxiety and delirium.
Sichuan Da Xue Xue Bao Yi Xue Ban 2013 Jul
PMID:[The hot point and controversy of clinical measures in critical are medicine]. 2405 20

<b>Objective:</b> To evaluate the feasibility and safety of applying enhanced recovery after surgery (ERAS) protocol in patients undergoing laparoscopic distal pancreatectomy. <b>Methods:</b> Data of 36 patients undergoing laparoscopic distal pancreatectomy from May 2016 to May 2017 in the First Affiliated Hospital, Zhejiang University School of Medicine were reviewed. The patients were divided into ERAS group (<i>n</i>=12) and control group (<i>n</i>=24). The patients in ERAS group received a series of enhanced recovery procedures, including multimodal analgesia, early off-bed activity and early oral food-taking, etc. Operation time, intraoperative blood loss, time to first flatus, postoperative complications, and length of postoperative hospital stay were evaluated. <b>Results:</b> There were no statistically significant differences in operation time and intraoperative blood loss between ERAS group and control group (all <i>P</i>>0.05). The time to first flatus and length of postoperative hospital stay were significantly shortened in ERAS group (all <i>P</i><0.05). The ERAS group had lower incidence of postoperative complications (41.7% vs. 66.7%), and the complications in ERAS group tended to be milder, but the differences failed to show statistical significance (all <i>P</i>>0.05). <b>Conclusion:</b> The ERAS protocol for laparoscopic distal pancreatectomy can significantly promote gastrointestinal function recovery and shorten postoperative hospital stay, and may reduce the incidence of postoperative complications.
Zhejiang Da Xue Xue Bao Yi Xue Ban 2017 May 25
PMID:[Application of enhanced recovery program in laparoscopic distal pancreatectomy]. 2965 65