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Query: UMLS:C0344307 (
analgesia
)
28,200
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Amethocaine
1% solution was mixed with equal volumes of water, 0.9% saline or 10% dextrose to prepare respectively, hypobaric, isobaric and hyperbaric solutions which were compared for intradural spinal anaesthesia in 60 patients. Thirty patients received 10 mg and 30 patients received 15 mg of amethocaine. Injections were made with the patients in the lateral recumbent position and the operating table was horizontal during and after injection. Equal numbers of patients and equal numbers of males and females received hypobaric, isobaric and hyperbaric solutions. The mean spread of
analgesia
after the hyperbaric solution was five dermatomes greater than after the other two solutions, but the extent of
analgesia
was not significantly different whether amethocaine 10 mg or 15 mg was injected. The mean duration of
analgesia
after the hyperbaric solution was 285 min compared with 332 min and 360 min after the isobaric and hypobaric solutions respectively. The mean duration of
analgesia
after amethocaine 15 mg was significantly greater than after 10 mg.
...
PMID:Effect of baricity on spinal anaesthesia with amethocaine. 742 30
We have compared the spread of subarachnoid hyperbaric amethocaine in adolescents with that in adults.
Amethocaine
8 mg in 2 ml of 10% glucose was injected through a 25-gauge spinal needle inserted at the L3-4 interspace in 21 adolescents aged 12-16 yr and in 111 adults aged 17-82 yr. Although we found no differences in height, weight or body mass index between the adolescents and adults, maximum spread of
analgesia
was significantly higher in the adolescents (median T3 (range T4-C5) than in the adults (T4 (T9-C7)). We conclude that subarachnoid injection of hyperbaric amethocaine produces an unexpectedly higher level of
analgesia
in adolescents than in adults.
...
PMID:Spread of subarachnoid hyperbaric amethocaine in adolescents. 757 57
Amethocaine
gel is a recently developed formulation of amethocaine, designed to provide percutaneous local anaesthesia. Its pharmacological characteristics coupled with a phase-change gel formulation may confer therapeutic advantages over existing preparations. Percutaneous local anaesthesia has increasing relevance in
analgesia
for paediatric procedures and superficial surgical operations.
...
PMID:Amethocaine gel for percutaneous local anaesthesia. 979 47
