Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Despite the initial claims that propoxyphene (Darvon) provides analgesia without risk of dependence, there is growing international recognition of its addictive potential, with documentation of both psychological dependence and physical withdrawal symptoms. However, many physicians remain uninformed of the true nature of the drug and its potential for abuse and addiction. In terms of frequency of addiction among users, propoxyphene may be less dangerous than most narcotics, but it is more available by prescription and less expensive then illegal opiates, making it a prime target for both abuse and addiction. At present, increased caution by prescribing physicians is indicated. Patients now taking the drug should be carefully monitored for signs of abuse or dependence.
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PMID:Propoxyphene dependence: an update. 731 31