Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To investigate the routine use of a skin stapling device for the closure of midline abdominal wounds, 48 patients were randomized to receive skin staples or subcuticular polydioxanone sutures. The mean (range) time for closure with staples was 8.0 (3.4-14.8) s cm-1 while subcuticular closure took 12.7 (9.6-28.0) s cm-1. The mean time saved per patient with skin staples was 77 s. Wound pain and requirements for analgesia were significantly lower in the sutured group. The mean cost per patient was 1.41 pounds for subcuticular closure and 7.72 pounds for stapling; the latter also incurred an additional cost of 6.27 pounds for staple removal. No clear benefit derives from the use of staples in the closure of abdominal wounds.
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PMID:Closure of laparotomy wounds: skin staples versus sutures. 146 95

Pain is a complex phenomenon that affects individuals in different ways. Wound pain is often seen as an inevitable consequence of wound care and many patients may suffer from chronic wound pain. One group of patients that presents a challenge in wound pain management are those with fungating malignant wounds. The effective management of wound pain may be compromised by inappropriate or non-existent pain assessment, the inefficient prescribing of analgesia, and confusion about the appropriate use of dressing products to reduce wound pain. Many healthcare professionals lack knowledge about pain and pain control and hold inappropriate beliefs and attitudes about analgesic medications, in particular relating to opioid drugs. This article aims to address these issues by providing a brief overview of pain physiology followed by strategies for pain assessment and options for the management of pain related to fungating wounds, including pharmacological treatments, wound care techniques and complementary therapies.
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PMID:Assessment and management of pain in fungating wounds. 1184 70