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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The Doppler effect and its application on the human body is described as well as its specific use in pediatric age: cerebral blood flow, liver and renal transplants, vascular-renal and portal hypertension and characterization of mass, tissue and structure. The results of 107 studies with Doppler duplex echograph on 86 neonates are analysed. The anterior and posterior cerebral arteries were sounded. The parameters taken into consideration were ten maximum systolic velocity (VS), the final diastolic velocity (VD), Bada's pulsatility index (IP) and the morphology of the curve. In 35 normal newborns the results were: maximum systolic velocity 24.08 +/- 4.30 cm/s, the final diastolic velocity 8.77 +/- 1.86 cm/s, Bada's pulsatility index. In the caesarean born neonates in both forms of anaesthesia, and those born by EVA delivery (stimulation, suction and analgesia) slight increases were observed, in comparison with the normal newborn group, in the maximum systolic velocity and Bada's pulsatility index.
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PMID:[Duplex Doppler echography as a non-invasive method of evaluating cerebral blood flux, in full-term newborns, in the immediate neonatal period]. 275

Preventive analgesia produced by ketorolac and metamizol was evaluated during a prospective study randomized in two groups. One hundred twenty children were included aged from 3 to 6 years who underwent surgery by different procedures. Analgesic dose was applied 15 min prior to surgery by intravenous (i.v.) via. Technique used was inhaled general anesthesia; use of opioids was avoided. Pain evaluation at the end of surgery (and during the following 48 to 72 h) as well as bleeding time, platelet count, and alterations in white blood cell count were dependent variables. As soon as patients arrived in the recovery room, pain was measured by modified McGrath scales and the chromatic EVA. In ketorolac group, 40% of children showed no pain and 55% presented mild to moderate pain (1-6). In metamizol group, 40% of children referred no pain, while 55% evaluated pain as minimal to moderate. Analgesia produced by both drugs presented no significant statistical diference (p > 0.5). Troughout followup, maximum pain referred had a values of 6 and 7, respectively, for ketorolac and metamizol. Fifteen min after analgesic dose, pain was referred as 3 and 4. No alterations were observed in bleeding time, platelet count, and white blood cell count. We conclude that both analgesics prevent hyperalgesia during post-surgical period.
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PMID:[Ketorolac vs metamizol preemptive analgesia in children]. 1975 21

The use of lipostructure to treat burn sequelae is more and more common today. The regeneration capacities of mesenchymal stem cells appear promising on this sequelae skin, which is poorly vascularized, retractile and often painful. The aim of our study is to establish the analgesic properties, and the functional and aesthetic improvements gained by using lipostructure to treat burn sequelae. Forty-three patients who received lipostructure for burn sequelae according to the Coleman method between 2005 and 2017 were selected. Results regarding aesthetic, analgesic and mobility gain were recorded, with a minimum follow-up of one year postoperatively. Our patients consisted of 32 women and 11 men, with a mean age of 31.7 years (15 to 64 years). The mean follow-up during the study was 49.8 months (2 to 205 months). Patients received an average of 1.3 (1 to 3) sessions of lipostructure with an average of 153 cc (10 to 1040 cc) per session. Sequela sites were the face for 13 patients, the upper limb for 13 patients, the lower limb for 16 patients and the trunk for 4 patients. Twelve patients had lesions on multiple locations. Twenty patients benefited from this surgery for purely aesthetic or functional reasons, and 23 for painful sequelae. A significantly lower EVA was observed after surgery and a functional gain thanks to the restoration of no longer painful amplitudes. An aesthetic gain was also reported in more than three quarters of cases. In two cases, the analgesic effect decreased after one year and required a second lipostructure. The use of lipostructure in burn sequelae has already proved its efficiency with regard to the functional aspect, aesthetics and also analgesia. However, the evaluation of results is based on scales that are still imperfect. Lipostructure is not the only type of surgery used in burn sequelae. Local plasty or skin grafts are also used, but they are more invasive and have no direct analgesic effect. Lipostructure is only possible on mature, soft and non-adherent scars in order not to traumatize adipose cells. Post-burn skin is defined by retractions and adhesions to deep planes, requiring heavy rehabilitation work beforehand. Finally, the effect is not always sustainable and the duration of efficiency remains unknown. Lipostructure has its place in the treatment of hyperalgic and unsightly burn sequelae that are responsible for a functional and social disability in the patient.
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PMID:??? 3086 60