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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In authors' opinion, the more precise methods for controlling the depth and efficiency of general anesthesia are those which are based on the direct control over the intraoperative status of the central nervous system which reflects the time course of the status in question. Whether monitoring of the early components of somatosensory evoked potentials could be used for multimodality anesthesia was analysed. As high as 50% or lower decreases in the amplitude of the complex N19-P23 were typical of adequate defense, irrespective of anesthesias. The authors provide evidence for the efficiency of their procedure for controlling the depth and efficiency of general anesthesia. Some electroencephalographic phenomena of anesthesia were analysed with computed monitoring. The authors showed that there was a relative value of such signs of inadequate anesthesia as interhemispheric asymmetry by the leading spectral frequency and the power index of deep rhythms. Despite the procedure used (neuroleptic analgesia, ataralgesia, inhalation anesthesia, etc.), the effective anesthesia exhibited pronounced power peaks, otherwise there was a chaotic activity of the central nervous system. The physiological and clinical values of the phenomena detected are discussed in the paper.
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PMID:[Electrophysiology of the central nervous system in effective anesthesia]. 762 92

The authors analyse the early components of somatosensory evoked potentials (SSEP) during anesthesia in prolonged and traumatic operations on the abdominal organs (gastrectomy, hemihepatectomy, pancreatoduodenal resection, etc.). A total of 69 patients were examined, among them 32 underwent operations under conditions of classical NLA, 16 with the narcotic analgetics replaced by moradol, and 21 under modified NLA with dalargin. The results of the study and analysis of literature data allow monitoring of the early components of somatosensory evoked potentials to be considered a highly sensitive test for appraising the depth and adequacy of the modern methods of general anesthesia and to be recommended for use, at least in particularly difficult and venturesome operations. It is shown that most significant in the discussed plan is not the absolute value, but changes of the N19-P23 amplitude in the stages of the operation. Increase of the studied SSEP component by 20% and more in relation to the basal level (SSEP amplitude in the patient after adequate preanesthesia) is evidence of insufficient analgesia. Change of N19-P23 latency is less demonstrative. Monitoring of the early components (N19-P23) of SSEP showed that to ensure effective analgesia in prolonged concurrent and combined operations, if the NLA method is chosen, administration of fentanyl in a dose of no less than 12 micrograms/kg/hour is necessary. It is shown that replacement of narcotic analgesics, within the limits of the conducted NLA, by moradol, an agent of the group of agonists-antagonists is poorly effective.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Intraoperative monitoring of abdominal organs under combined general anesthesia]. 790 25

Somatosensorially evoked and auditorially evoked potentials (SSEP and AEP) were evaluated in 75 patients in different stages of general anesthesia during surgical procedures made on the lungs. N19-P23 latent increases of SSEP denoted an adequate level of analgesia. The AEP evaluation is recommended for monitoring the amnesia status during general anesthesia. N1 depression, long-latent N2 and P300 as well as disappearance of AEP and intracerebral asymmetry inversion with predominance of the bioelectric activity in the right cerebral hemisphere are regarded as objective signs of amnesia induction.
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PMID:[Monitoring of analgesia and amnesia during the general anesthesia in surgeries made on the lungs]. 1531 49